Relationship Between Psychological Responses and the Appraisal of Risk Communication During the Early Phase of the COVID-19 Pandemic: A Two-Wave Study of Community Residents in ChinaPublic Health Published on 2020-09-302022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] addition Affect affected Anxiety appraisal association Baseline assessment China collected communication Community Complete Contagion COVID-19 Data collection demonstrated emotion emotional females helping high-risk area initial Longitudinal data mental health novel coronavirus disease outbreak Outbreaks phase preventive measures Psychological questionnaire Questionnaires relationship resident response responses retained risk Risk communication Risk perception suggested susceptibility virus Wave Wuhan [DOI] 10.3389/fpubh.2020.550220 PMC 바로가기 [Article Type] Public Health
Covid-19: Perspectives on Innate Immune EvasionImmunology Published on 2020-09-302022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Antigen presentation approach caused contribute coronavirus Coronavirus disease 2019 cytokine - immunological terms Cytokine storm driving Host immune evasion immune response impair IMPROVE induce Infection Innate innate immune response Innate immunity innnate immune interferon macropahge mechanism MHC class I MHC trafficking Mortality outbreak pandemic status Pathogenesis pathophysiology responses SARS-CoV-2 SARS-COV-2 infection suppress understanding Vaccine virus clearance [DOI] 10.3389/fimmu.2020.580641 PMC 바로가기 [Article Type] Immunology
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses Research Published on 2020-09-302022-10-05 Journal: Nature [Category] 유전자 메커니즘, 임상, 치료기술, 치료제, [키워드] acute respiratory syndrome Adults age antibody Antibody Response BNT162b1 CD4+ CD4+ T cell CD4+ T cells CD8+ CD8+ T cell Cohort Concentration coronavirus disease Coronavirus-2 COVID-19 COVID-19 vaccine cytokine response dose effective elicit elicited ENCODE fraction geometric mean healthy immune response individual individuals mechanisms MOST mRNA vaccine neutralized non-randomized nucleoside-modified mRNA observer-blinded Open-label pandemic participant placebo-controlled produced PROTECT pseudovirus RBD RBD-binding IgG Receptor binding domain reported response responses robust SARS-CoV-2 SARS-CoV-2 spike variants sera serum Spread T cell T cell response T helper the SARS-CoV-2 titre Tolerability Trial vaccination Vaccine vaccine trial [DOI] 10.1038/s41586-020-2814-7 [Article Type] Research
Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ ResponsivenessArticle Published on 2020-09-292022-10-31 Journal: Cells [Category] COVID-19, [키워드] caused COVID-19 cytokine cytokine production Cytokine storm degranulation demonstrated dendritic cell dendritic cells disease driver feature forms functional Health highlight hyperinflammation IFN alpha immature Impaired innate immune Innate immunity Interaction interferon involved low expression maturation mechanisms monocyte Monocytes NETosis neutrophil Neutrophils pandemic disease PD-L1 phenotype profile reduce Research responses responsiveness SARS-CoV-2 SARS-CoV-2 virus severity of COVID-19 signature therapeutic targeting with COVID-19 [DOI] 10.3390/cells9102206 PMC 바로가기 [Article Type] Article
Prevalence and Predictors of Emotional Eating among Healthy Young Saudi Women during the COVID-19 PandemicArticle Published on 2020-09-242022-10-30 Journal: Nutrients [Category] Coronavirus, SARS, [키워드] activity age Anxiety asked BMI body mass index collected data Coronavirus 2019 correlated COVID-19 Depression eating emotional Emotional Eating Scale Energy intake fat food consumption Frequency Generalized healthy IMPROVE Increased intake increased the risk index investigated less mandatory mental symptom mitigate moderate MOST obesity pandemic Perceived Stress Scale physical activity Pittsburgh predictor Prevalence prevalent Quality quarantine reported responses scale Sleep Stress sugar women young women [DOI] 10.3390/nu12102923 PMC 바로가기 [Article Type] Article
Azithromycin in viral infectionsReview Published on 2020-09-232022-10-29 Journal: Reviews in Medical Virology [Category] COVID-19, [키워드] Activation affecting antibiotic Apoptosis Azithromycin Bacterial clinical study conducted coronavirus Coronaviruses COVID‐19 COVID‐19 degranulation disease Ebola effective ENhance expression GM‐CSF granulocyte in silico in viral in vitro Infection infections Inflammatory response influenza A inhibit inhibiting interferon investigated Lysosomes Macrolide mammalian mechanism mechanisms murine mycobacterial Neutrophils NFκB Novel coronavirus infection Patient pattern recognition receptor Randomised clinical trials randomised trial data Rapamycin reduce Replication responses review rhinovirus SARS‐CoV‐2 SARS‐CoV‐2 T cell target therapeutic TNF Treatment Trial type I virus Zika virus [DOI] 10.1002/rmv.2163 PMC 바로가기 [Article Type] Review
Medicine and surgery residents’ perspectives on the impact of COVID-19 on graduate medical educationResearch Article Published on 2020-09-132022-10-29 Journal: Medical Education Online [Category] Coronavirus, MERS, SARS, [키워드] Administered Analysis analyzed Anxiety Characteristics COVID-19 COVID-19 crisis COVID-19 pandemic determine Effect effective Factor female gender groups Health help hospital Interaction less Medicine mitigate MONITOR pandemic Patient Personal protective equipment Perspective PPE Primary outcome quarantine Regression analyses Resident education resource responses secondary significantly social distancing Stress Stressor stressors suggested surgical Telemedicine Virtual Learning Volume [DOI] 10.1080/10872981.2020.1818439 PMC 바로가기 [Article Type] Research Article
Accurate serology for SARS-CoV-2 and common human coronaviruses using a multiplex approachResearch Article Published on 2020-09-082022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] antibody approach circulating clinical evaluation coronavirus COVID-19 COVID-19 cohort diagnostics epidemiological evaluate evaluated heterogeneous human coronavirus human coronaviruses identify immune profiling immunoassay micro-array multiplex N antigen Patient Prevalence Protein provided public health Quantitative Research question responses SARS-CoV-2 SARS-CoV-2 antibody responses SARS-CoV-2 IgG antibody SARS-CoV-2 pandemic SARS-CoV-2 S1 sensitivity Serological assay serology Severity of disease specificity subset Support Symptom [DOI] 10.1080/22221751.2020.1813636 PMC 바로가기 [Article Type] Research Article
Ixazomib-based frontline therapy in patients with newly diagnosed multiple myeloma in real-life practice showed comparable efficacy and safety profile with those reported in clinical trial: a multi-center studyOriginal Article Published on 2020-09-062022-10-28 Journal: Annals of Hematology [Category] COVID-19, [키워드] Abnormalities adverse event AEs applied clinical trials comparable Complete Cooperative Coverage COVID-19 Cyclophosphamide diagnosed Doxorubicin effective Effectiveness Efficacy and safety frontline group Health Infectious disease inhibitor ISS Ixazomib less limitation Local median median age median time Multiple myeloma Myeloma occurred Patient patients performed reached real-world regimen regimens remained reported responses shown stage III Support survival therapy Tolerance Toxicity Treatment [DOI] 10.1007/s00277-020-04234-9 PMC 바로가기 [Article Type] Original Article
Cardiovascular Damage in COVID-19: Therapeutic Approaches Targeting the Renin-Angiotensin-Aldosterone SystemReview Published on 2020-09-042022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] ACE2 ACE2/Ang-(1–7)/MasR Activation acute respiratory syndrome age agonist alterations angiotensin-converting enzyme inhibitor anomalies Antiviral apoptotic ARB association blocker cardiovascular cardiovascular damage Cell clinical trial components Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patients damage decrease disease endothelial cells Genetic help homeostasis hypercoagulable hyperinflammation Hyperinflammatory hypertension hypertensive immunomodulator IMPROVE individual infect Infection liver lung Mortality multiple tissue outcome Pathologies pathology pathway peptides plasma polymorphism RAAS receptor reduce regulate responses SARS-CoV-2 SARS-COV-2 infection severity sex hormone soluble ACE2 Stage susceptibility System targeting Therapies therapy thrombotic Treatment Vaccine vessel viral particle viral propagation [DOI] 10.3390/ijms21186471 PMC 바로가기 [Article Type] Review