ACE – Page 8 – Communicable Diseases Research

Comprehensive landscape of the renin-angiotensin system in Pan-cancer: a potential downstream mediated mechanism of SARS-CoV-2

Research Paper

Published on 2021-09-032022-10-29
Journal: International Journal of Biological Sciences [Category] COVID-19, MERS, SARS,

Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs

Observational Study

Published on 2021-09-022022-10-05
Journal: Human vaccines & immunotherapeutics [Category] SARS, 임상,

[키워드] 28-day mortality 95% CI ACE ACE inhibitor ACE inhibitors ACEIs activity angiotensin receptor blocker Angiotensin receptor blockers ARB ARBs Belgium Case-control characterized clinical trial Combination combination treatment COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients determine drug Endothelial cell Endothelial dysfunction help hospital Hospital mortality hospitalized COVID-19 patients immunometabolism IMPROVE In-hospital maintain Mortality observational study pathogenesis of COVID-19 Propensity score receptor reduced reduction in statins survival treated Treatment unlikely Vaccine
[DOI] 10.1080/21645515.2021.1920271 PMC 바로가기 [Article Type] Observational Study

ACE I/D polymorphism and epidemiological findings for COVID-19: One year after the pandemic outbreak in Europe

Correspondence

Published on 2021-09-012022-10-05
Journal: The Journal of Infection [Category] SARS, 유전자 메커니즘,

[키워드] ACE epidemiological finding Europe I/D polymorphism outbreak pandemic
[DOI] 10.1016/j.jinf.2021.06.002 [Article Type] Correspondence

Repurposing of FDA-approved antivirals, antibiotics, anthelmintics, antioxidants, and cell protectives against SARS-CoV-2 papain-like protease

FDA 승인 항바이러스제, 항생제, 구충제, 항산화제 및 SARS-CoV-2 파파인 유사 프로테아제에 대한 세포 보호제의 용도 변경

Article

Published on 2021-09-012022-09-11
Journal: Journal of biomolecular structure & dynamics [Category] SARS, 신약개발, 진단, 치료제,

[키워드] 6-mercaptopurine ACE acting Analysis Antacid Antibiotics anticancer drugs antimicrobial antioxidant antioxidants Antiviral antivirals approved drug benzimidazole binding affinities binding affinity binding energy binding pattern binding patterns blocker bypassing candesartan Cell contagious coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 patients Critical demonstrated docking score doripenem drug Drug discovery Drug repurposing drugs expected Famotidine fatal disease FDA-approved drugs followed by Guidance highest inhibitor list losartan MD simulations mercaptopurine molecular molecular dynamics moroxydine NAD+ oxiglutatione Papain Papain-like protease pharmacokinetic Phenformin PLPro primer protease Protective provided quercetin quercitrin receptor repurposing Ritonavir Safe SARS CoV SARS-CoV-2 sulfaguanidine surface area systemically Toxicity treat Vaccine development valsartan was used zanamivir
[DOI] 10.1080/07391102.2020.1784291 PMC 바로가기 [Article Type] Article

Pathophysiology of COVID-19: Everywhere You Look You Will See ACE 2 !

Medicine

Published on 2021-08-272022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Interaction of SARS-CoV-2 spike protein with angiotensin converting enzyme inhibitors and selected compounds from the chemical entities of biological interest

Research

Published on 2021-08-252022-10-28
Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19,

Coronavirus disease 2019 (COVID-19): Multisystem review of pathophysiology

Review

Published on 2021-08-232022-10-28
Journal: Annals of Medicine and Surgery [Category] COVID-19,

[키워드] abnormality ACE Affect affected affecting ameliorated angiotensin Asymptomatic disease caused complications Coronavirus disease 2019 COVID-19 COVID-19 infection cytokine Cytokine storm syndrome distress hypercoagulable infected patients life-threatening manifestation marker mechanism mechanisms Mild morbidity and mortality multiple organ multiple organ involvement multiple organs organ system pandemic Pathogenesis pathology pathophysiology Patient predictor pro-inflammatory pulmonary symptoms receptor renal respiratory SARS CoV-2 Symptoms syndrome Treatment Trial Venous Thromboembolism viral entry viral infection
[DOI] 10.1016/j.amsu.2021.102745 PMC 바로가기 [Article Type] Review

The Angiotensin Converting Enzyme Deletion/Deletion Genotype Is a Risk Factor for Severe COVID-19: Implication and Utility for Patients Admitted to Emergency Department

Observational Study

Published on 2021-08-202022-10-04
Journal: Medicina [Category] MERS, SARS, 임상,

[키워드] ACE ACE2 activity affected age alteration angiotensin angiotensin converting enzyme Angiotensin-converting enzyme ARDS association caused Complication conducted correlated COVID-19 COVID-19 disease Department described distress Emergency Evolution Factor Genetic Genetic predisposition Genotype healthy controls hypothesised increase Italy majority marker material Mutation Naple observation outcome Patient performed Pneumonia polymorphism positive Prevalence Result risk risk factor SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe COVID-19 patient Severe COVID-19 pneumonia severity significantly higher subject syndrome tested the disease thrombosis unit Venous Thromboembolism VTE
[DOI] 10.3390/medicina57080844 PMC 바로가기 [Article Type] Observational Study

ACE Gene Variants Rise the Risk of Severe COVID-19 in Patients With Hypertension, Dyslipidemia or Diabetes: A Spanish Pilot Study

ACE 유전자 변이는 고혈압, 이상지질혈증 또는 당뇨병 환자에서 심각한 COVID-19의 위험을 높입니다: 스페인 파일럿 연구

Endocrinology

Published on 2021-08-192022-09-11
Journal: Frontiers in Endocrinology [Category] MERS, 변종,

[키워드] ACE acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition adjusted age aldosterone angiotensin angiotensin converting enzyme association Asymptomatic BMI caused Comorbidities Comorbidity contribute coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 prognosis COVID-19 severity develop diabetes Diabetic diabetic patient diabetic patients direct association disease severity dyslipidemia enzyme explain Factor form G allele Gender genetic background genetic data Genotype Health hospital Hospitalized Host hypertension hypertensive hypertensive patients ICU identify Infection knowledge lead management marker Mortality number of comorbidities outcome Patient polymorphism Polymorphisms poor prognosis Precision Predictive RAAS Renin respiratory risk risk factor SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 infected patients serum severe acute respiratory syndrome Coronavirus severe COVID-19 severity severity of COVID-19 Sex Spanish susceptibility symptomatic the disease Variability
[DOI] 10.3389/fendo.2021.688071 PMC 바로가기 [Article Type] Endocrinology

Characterization of ACE Inhibitors and AT 1 R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model

Article

Published on 2021-08-102022-10-29
Journal: International Review of Cell and Molecular Biology [Category] COVID-19,