adverse outcomes – Page 8 – Communicable Diseases Research

Immunopathology and Immunosenescence, the Immunological Key Words of Severe COVID-19. Is There a Role for Stem Cell Transplantation?

Cell and Developmental Biology

Published on 2021-09-142022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

Homelessness during COVID-19: challenges, responses, and lessons learned from homeless service providers in Tippecanoe County, Indiana

Research

Published on 2021-09-102022-10-28
Journal: BMC Public Health [Category] Coronavirus, SARS,

COVID-19 susceptibility variants associate with blood clots, thrombophlebitis and circulatory diseases

Covid-19 감수성 변이체는 혈전, 혈전증 및 순환 질환과 관련이 있습니다.

Research Article

Published on 2021-09-032022-09-10
Journal: PLoS ONE [Category] SARS, 변종, 유전자 메커니즘,

[키워드] adverse outcome adverse outcomes Analysis approach association Blood blood clot Blood clots comorbid condition comorbid conditions COVID-19 COVID-19 susceptibility diabetes disease Effects epidemiological studies evaluated event General practice Genome-wide association studies higher risk Hospital Episode Statistics identify increased risk individual Inflammatory loci lung Lungs other disease other diseases outcomes performed phenotypic data phlebitis phlebitis and thrombophlebitis Practice Predictive reported risk severity Spectrum Stratification susceptibility thrombophlebitis traits UK biobank utilised variant vascular disease
[DOI] 10.1371/journal.pone.0256988 PMC 바로가기 [Article Type] Research Article

Complement levels at admission as a reflection of coronavirus disease 2019 (COVID-19) severity state

코로나바이러스 질병 2019(COVID-19) 심각도 상태를 반영하여 입원 시 보완 수준

Article

Published on 2021-09-012022-09-11
Journal: Journal of medical virology [Category] SARS, 바이오마커,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus 2 ADAMTS13 Admission adverse outcome adverse outcomes analyzed association benefit Blood blood sample Blood samples C3a C3a/C3 Clinical improvement complement complement system confounders coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation correlations Course COVID-19 COVID-19 illness COVID-19 patient COVID-19 severity disease severity displaying elevated emergency department enrolled Evidence evidence of fibrinogen highest Hyperactivation hyperinflammation Hyperinflammatory implicated infected patients inflammatory biomarkers investigated moderate organ damage over parameter Patient phenotype plasminogen predict presenting Primary outcome progression Research respiratory SARS-CoV-2 SARS-CoV-2 hyperinflammation secondary outcome severe acute respiratory syndrome Coronavirus severe COVID-19 illness severe disease severity significantly therapy thrombotic thrombotic microangiopathy tissue
[DOI] 10.1002/jmv.27077 PMC 바로가기 [Article Type] Article

Rhabdomyolysis is Associated with In-Hospital Mortality in Patients with COVID-19

횡문근 융해증은 COVID-19 환자의 병원 내 사망률과 관련이 있습니다

Article

Published on 2021-09-012022-09-11
Journal: Shock (Augusta, Ga.) [Category] SARS, 치료기술,

[키워드] 95% CI Abnormalities Activation adverse outcome adverse outcomes Analysis clinical feature Clinical features Coagulation cohort study Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients creatine creatine kinase Deterioration Early detection effective intervention evaluate greater help higher risk hospitalized patient Huoshenshan Hospital In-hospital death incidence independent risk factor independent risk factors Inflammation intensive care intensive care unit Kidney injury Laboratory Laboratory test marker mechanical ventilation Myoglobin outcome outcomes Patient patients with COVID-19 reduce mortality Regression model retrospective rhabdomyolysis serum single-center viral clearance viral infectious diseases with COVID-19 Wuhan Wuhan, China
[DOI] 10.1097/SHK.0000000000001725 PMC 바로가기 [Article Type] Article

Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?

Review article

Published on 2021-09-012022-10-05
Journal: Ageing research reviews [Category] SARS, 유전자 메커니즘,

[키워드] ACE2angiotensin converting enzyme 2 ADAlzheimer’s disease adverse outcome adverse outcomes affected Alzheimer’s disease amyloid beta amyloid beta precursor protein angiotensin converting enzyme 2 APOE4apolipoprotein E4 genotype apolipoprotein E4 genotype APPamyloid beta precursor protein Aβamyloid beta BMIbody metabolic index body metabolic index Can Central nervous system CNSCentral Nervous System Comorbidity condition coronary disease Coronavirus disease 2019 COVID-19 COVID-19coronavirus disease 2019 COXcytochrome c oxidase activity cyclophilin D CypDcyclophilin D cytochrome c oxidase activity Dementia Diabetes Mellitus Disease progression DMVdouble membrane vesicles double membrane vesicles Effect Factor genetics global pandemic greater healthy HIF-αhypoxia inducible factor-Iα hypertension hypoxia inducible factor-Iα IFNinterferon impacted interferon long-lasting MCImild cognitive impairment medical system metabolism MFRTAmitochondrial free radical theory of aging MHVmouse hepatitis virus Mild cognitive impairment mitochondrial DNA mitochondrial free radical theory of aging mitochondrial microRNAs MitomiRsmitochondrial microRNAs mouse hepatitis virus MtDNAmitochondrial DNA neuropsychiatric Inventory-Questionnaire nitric oxide NONitric Oxide novel coronavirus disease NPIQneuropsychiatric Inventory-Questionnaire obesity open-reading frames ORFopen-reading frames pandemic PARPpoly-ADP-ribose polymerase patients Pneumonia poly-ADP-ribose polymerase Population presenilin 1 presenilin 2 progression PS1presenilin 1 PS2presenilin 2 question RAASrenin-angiotensin-aldosterone system reactive oxidative species reduce renin-angiotensin-aldosterone system risk ROSreactive oxidative species SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SCDsickle cell disease severe acute respiratory syndrome coronavirus 2 Sickle cell disease susceptible T2Dtype 2 diabetes those with comorbidities TMPRSS2transmembrane protease serine 2 TNF-αtumor necrosis factor α transmembrane protease serine 2 triglyceride and glucose index tumor necrosis factor α TyGtriglyceride and glucose index type 2 diabetes virus WDWestern diet Western diet while
[DOI] 10.1016/j.arr.2021.101406 [Article Type] Review article

Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

영국에서 역효과 위험이 높은 사람들을 대상으로 코로나19가 의심되는 지역사회 치료를 위한 독시사이클린(원칙): 무작위, 통제, 공개, 적응 플랫폼 시험

Randomized Controlled Trial

Published on 2021-09-012022-09-11
Journal: The Lancet. Respiratory Medicine [Category] Fulltext, SARS, 임상, 치료법,

[키워드] absence adaptive Adaptive platform trial adaptive randomisation adverse outcome adverse outcomes age analysed assigned Asthma Bayesian BCI benefit body-mass body-mass index clinical trial clinical trials clinically Community Comorbidities Comorbidity contributed COVID-19 credible interval criterion death defined Department diabetes disease doxycycline Efficacy Endpoint enrolled Evidence evidence of female FIVE Follow-up greater groups hazard ratio heart disease hepatic impairment high risk Hospital admission Hospital admissions hospitalisation hypertension Innovation Intention intention to treat interval Intervention ISRCTN Lung disease male manuscript median time Mild multi-arm National neurological obesity occurred Older once daily Open-label participant participants randomly assigned Patient platform Platform trial positive PCR test primary analysis primary care principle Probability randomisation randomised Randomised trial Randomly reductions in Registered reported respiratory symptom respiratory symptoms SARS-COV-2 infection stroke Support the mean Time to recovery treat treating COVID-19 Treatment treatment for COVID-19 Trial usual care weakened immune system
[DOI] 10.1016/S2213-2600(21)00310-6 PMC 바로가기 [Article Type] Randomized Controlled Trial

Diagnostic performance and clinical implications of rapid SARS-CoV-2 antigen testing in Mexico using real-world nationwide COVID-19 registry data

실제 전국 COVID-19 레지스트리 데이터를 사용하여 멕시코에서 빠른 SARS-COV-2 항원 테스트의 진단 성능 및 임상 적 영향

Research Article

Published on 2021-08-312022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% CI 95%CI Accuracy adverse outcome adverse outcomes age alternative alternatives analyzed Area AUROC caution Chain Reaction changes in clinical implication Comorbidities Comorbidity Course COVID-19 diagnostic Epidemic evaluated False negative false negative results higher risk Hospitalization implementation intubation location measure Mexico City MONITOR Mortality Negative predictive value Older outcome PCR testing polymerase chain polymerase chain reaction positive predictive values predictor qRT-PCR Quantitative Rapid rapid antigen test Rapid antigen tests receiver receiver operating characteristic receiver operating characteristic curve registry data Result reverse transcription risk SARS-CoV-2 antigen SARS-COV-2 infection SARS-CoV-2 testing sensitivity severe COVID-19 specificity symptom onset
[DOI] 10.1371/journal.pone.0256447 PMC 바로가기 [Article Type] Research Article

Risk, Course, and Effect of SARS-CoV-2 Infection in Children and Adults with Chronic Inflammatory Bowel Diseases

Review

Published on 2021-08-302022-10-31
Journal: Children [Category] COVID-19,

[키워드] ACE2 Admission adverse outcomes Angiotensin converting enzyme-2 anti-TNF Bacterial infection benefit biologic Biologic drugs characteristic chronic Clinical characteristics contrary Corticosteroids COVID-19 COVID-19 infection Crohn’s disease Cytokine storm death disease disease course drug drugs Effect epidemiological data excluded facilitate form IBD ICU immune system immunomodulators immunosuppressive therapies Immunosuppressive treatment increased risk Infection Inflammatory bowel disease infliximab Influenza intensive care Patient patients Pneumonia receptor reduce mortality replication of SARS-CoV-2 SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 shown suppress susceptibility Tocilizumab Topic treated ulcerative colitis
[DOI] 10.3390/children8090753 PMC 바로가기 [Article Type] Review

Effect of Continuous Electrocardiogram Monitoring on Detection of Undiagnosed Atrial Fibrillation After Hospitalization for Cardiac Surgery A Randomized Clinical Trial

Research

Published on 2021-08-272022-10-29
Journal: JAMA Network Open [Category] COVID-19, MERS,

[키워드] 12-lead electrocardiogram 24 hour 6 hour 95% CI absolute difference adverse outcomes after cardiac surgery age Analysis anticoagulation Atrial fibrillation benefit Can cardiac clinical conducted congestive heart failure Continuous continuous monitoring COVID-19 pandemic cumulative death defined detection determine diabetes discharge Effect electrocardiogram ENhance enrolled Enrollment female fibrillation finding Follow-up greater high risk hospital discharge Hospitalization hypertension Importance intent-to-treat intervention group investigator-initiated less major bleeding measure median MONITOR monitoring multicenter Myocardial infarction nervous system objective occurred Open-label participant Patient patients randomized persist Point postoperative primary end point Primary outcome randomization randomized clinical trial Registration Relevance Result risk factor Sample size secondary outcome setting Sex significant increase significantly stroke surgery surgical therapy Thromboembolism Trial usual care usual care group vascular disease women
[DOI] 10.1001/jamanetworkopen.2021.21867 PMC 바로가기 [Article Type] Research