Association of viral load with age, gender, disease severity, and death in severe acute respiratory syndrome coronavirus 2 variantsArticle Published on 2022-07-012023-07-08 Journal: Journal of medical virology [Category] COVID19(2023년), [키워드] Alpha variant Ct value delta variant SARS-CoV-2 viral loads [DOI] 10.1002/jmv.27677
A qualitative RT-PCR assay for the specific identification of the SARS-CoV-2 B.1.1.529 (Omicron) Variant of ConcernSARS-CoV-2 B.1.1.529(Omicron) 변형 우려의 특정 식별을 위한 정성적 RT-PCR 분석Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Alpha Alpha variant Alpha VOC B.1.1.529 B.1.1.7 B.1.351 B.1.429 B.1.526 B.1.617.1 B.1.617.2 Beta can be used circulating clinical sample clinical samples collected Combination concern copy numbers Delta detect develop Epsilon Gamma Genome in silico Iota lineages negative controls non-specific omicron P.1 performed positive replaced REPLACED BY RNA RNA genome RT-PCR RT-PCR assay SARS-CoV-2 Sequencing Specific Specific identification. specificity the SARS-CoV-2 variant virus VoC were used Wuhan [DOI] 10.1016/j.jcv.2022.105191 PMC 바로가기 [Article Type] Article
Tracking of SARS-CoV-2 Alpha variant (B.1.1.7) in Palestine팔레스타인에서 SARS-CoV-2 알파 변종(B.1.1.7) 추적Article Published on 2022-07-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant Analysis analyzed B.1.1.7 bootstrap clade Cluster collected COVID-19 COVID-19 mortality COVID-19 pandemic Diagnosis disease severity effective F-statistic gene flow Genetic variation genetics genome sequence homogenous Hypothesis impacted introduced Nablus new SARS-CoV-2 Palestine peaked Phylogenetic tree Population genetics remains uncertain replaced SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 variants sequenced statistically statistically significant supported Tajima therapy Transmission Vaccine-induced immunity variant virulence WGS whole genome sequence wild type [DOI] 10.1016/j.meegid.2022.105279 PMC 바로가기 [Article Type] Article
Immature granulocytes: Innovative biomarker for SARS‑CoV‑2 infection미성숙 과립구: SARS‑CoV‑2 감염에 대한 혁신적인 바이오마커Article Published on 2022-07-012022-09-11 Journal: Molecular medicine reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 치료기술, [키워드] acute pancreatitis acute respiratory syndrome addition age Alpha Alpha variant Analysis antiviral immune response Bacterial bacterial and fungal infections Biomarker Biomarkers Bone marrow Cardiopulmonary cardiopulmonary bypass clinical conditions Comorbidities complications confounders coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 critical cases Defense disease severity duration of hospitalization evaluate evaluated fungal infections granulocyte Granulocytes greater Host host defense immature immature granulocytes in viral include Increased independent Infection infections infectious complication Infectious complications intubation involved Logistic regression analysis Male sex Mortality multivariate logistic regression neutrophil Neutrophils Numerous outcomes Pancreatitis Patient patients hospitalized Peripheral blood precursor precursors presence of comorbidity present prognostic biomarker reported Research respiratory severe acute respiratory syndrome Coronavirus severe and critical cases severity significantly syndrome systemic inflammatory response systemic inflammatory response syndrome variant Viral viral infections was measured [DOI] 10.3892/mmr.2022.12733 PMC 바로가기 [Article Type] Article
SARS-COV-2 RBD (Receptor binding domain) mutations and variants (A sectional-analytical study)SARS-COV-2 RBD(수용체 결합 도메인) 돌연변이 및 변이체(섹션 분석 연구)Article Published on 2022-07-012022-09-11 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] ACE2 receptor Alpha alpha and delta variants Alpha variant Amino acid amino acid substitutions amino acids amplified B.1.1.529 B.1.1.7 binding domain binding the receptor-binding body pain chill chills circulation Clinical outcome clinical outcomes Clinical sign Clinical signs cross-sectional D614G delta variant domain Effect enrolled essential amino acids Fever Frequency highest host cells identify Infection lung involvement mutant strain Mutation mutations N501Y omicron Omicron variant outcomes Pain pangolin Patient qRT-PCR RBD RBD region Receptor-binding domain SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV2 sequenced spike Spike protein strain T478K the patient the RBD the SARS-CoV-2 variant variants variants of concern variants of interest Variation viral infection virus VOCs VOIs [DOI] 10.1016/j.micpath.2022.105595 PMC 바로가기 [Article Type] Article
Replacement of the Alpha variant of SARS-CoV-2 by the Delta variant in Lebanon between April and June 2021Article Published on 2022-07-012022-11-16 Journal: Microbial Genomics [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] age Alpha variant ARTIC protocol bioinformatics changed circulating circulation community transmission country COVID-19 COVID-19 infection COVID-19 pandemic delta variant Eastern Mediterranean Region expand Genome Genome sequencing genomic Genomic epidemiology increase in introduced Limited Lineage nine peaked Prospective remains uncertain replaced replacement rising SARS-CoV-2 SARS-CoV-2 genome selected sequenced Sequencing Sex Surveillance surveillance network Travel variant [DOI] 10.1099/mgen.0.000838 PMC 바로가기
Comparative characterization of SARS-CoV-2 variants of concern and mouse-adapted strains in mice마우스에서 우려되는 SARS-CoV-2 변이체 및 마우스 적응 균주의 비교 특성화Comparative Study Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha Alpha variant Amino acid Beta Beta variant caused changes in comparable Comparative cytokine cytokine assay Delta delta variant Evolution of SARS-CoV-2 global health Health highlighting Human indicated infect investigated isolates Laboratory lung Lung pathology Lungs MASCp6 mice Mild mouse-adapted strain mouse-adapted strains Mutation pathogenic pathogenicity raising RBD Receptor-binding domain Replication risk SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 mouse-adapted strains SARS-CoV-2 variant SARS-CoV-2 variants spillover risk sustained the RBD the receptor-binding domain variant variants variants of concern VoC VOCs wildtype [DOI] 10.1002/jmv.27735 PMC 바로가기 [Article Type] Comparative Study
Receptor-Binding-Motif-Targeted Sanger Sequencing: a Quick and Cost-Effective Strategy for Molecular Surveillance of SARS-CoV-2 Variants수용체 결합 모티브 표적 생어 시퀀싱: SARS-CoV-2 변이체의 분자 감시를 위한 빠르고 비용 효율적인 전략Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adopted aligned Alpha Alpha variant B.1.1.529 B.1.1.7 B.1.617.2 causative agent changes in CLC Clinical use coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Critical death Delta delta variant develop disease spread Genome gold gold standard Infection involved Lineage lineages modifications molecular mutate Mutation mutations nasal nasal swab nasal swabs nucleocapsid omicron Omicron variant Omicron variants pandemic prevalent Prevent public health receptor-binding motif Receptor-binding motif (RBM) resource Saliva Sanger sequencing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence sequences Sequencing severe acute respiratory syndrome Coronavirus Spike protein Spread Strategy Surveillance swab samples the disease variant variant surveillance. variants WGS whole-genome sequencing [DOI] 10.1128/spectrum.00665-22 PMC 바로가기 [Article Type] Article
Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa Research Published on 2022-06-272022-10-05 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval acute respiratory syndrome addition Alpha variant Amino acid animal hosts chronic infection contributing to coronavirus COVID-19 delta variant dispersal emergence Evolution growth advantage Hypothesis infections L452R Lineage lineages multinomial logistic regression omicron per day proxy marker Q493 replaced responsible S-gene SARS-CoV-2 sequenced South South Africa Spike protein variant virus wild-type [DOI] 10.1038/s41591-022-01911-2 [Article Type] Research
Detection of SARS-CoV-2 intra-host recombination during superinfection with Alpha and Epsilon variants in New York City뉴욕시에서 알파 및 엡실론 변이체로 중복 감염 중 SARS-CoV-2 숙주 내 재조합 검출Article Published on 2022-06-252022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, 치료법, 치료제, [키워드] allele Alpha Alpha variant B.1.1.7 B.1.429 classic coding regions Coronavirus replication detection Diversity Epsilon feasible full genome sequencing functions generate genetic diversity Genome genome sequence genomes Haplotype Host identify independent individual infect New York City nucleocapsid Occurrence ORF pathogen Pathogens Recombination reveal S gene SARS-CoV-2 superinfection Support variant virus [DOI] 10.1038/s41467-022-31247-x PMC 바로가기 [Article Type] Article