Symptoms at disease onset predict prognosis in COVID-19 diseaseArticle Published on 2022-12-012023-07-07 Journal: The Libyan journal of medicine [Category] COVID19(2023년), [키워드] ARDS COVID-19 outcome SARS-CoV-2 Symptoms [DOI] 10.1080/19932820.2021.2010338 PMC 바로가기
Effects of rescue inhaled nitric oxide on right ventricle and pulmonary circulation in severe COVID-related acute respiratory distress syndromeArticle Published on 2022-12-012023-07-08 Journal: Journal of critical care [Category] COVID19(2023년), [키워드] ARDS COVID echocardiography Inhaled nitric oxide right ventricle Systolic pulmonary arterial pressure. [DOI] 10.1016/j.jcrc.2022.153987 PMC 바로가기
Effects of High PEEP on Intrapulmonary Shunt Ratio in Patients With SARS-CoV-2-Induced ARDSArticle Published on 2022-11-012023-07-10 Journal: Respiratory care [Category] COVID19(2023년), [키워드] ARDS COVID-19 intrapulmonary shunt ratio pulmonary artery catheter Recruitment-to-inflation ratio SARS-CoV-2 [DOI] 10.4187/respcare.09941
New insights into development and mortality of COVID-19-associated pulmonary aspergillosis in a homogenous cohort of 1161 intensive care patientsArticle Published on 2022-11-012022-11-15 Journal: Mycoses [Category] 진단, [키워드] acute respiratory distress acute respiratory distress syndrome analysed ARDS Cohort collected Computed tomography consolidation COVID-19-associated pulmonary aspergillosis defined development diabete diabetes disease distress Factor Fever Glucocorticoid treatment Glucocorticoids hemoptysis high mortality homogenous hospitalised immune dysregulation intensive care patient laboratory data large cohort lung lesion lymphopenia Mortality multivariable analysis Multivariable models neutrophilic leukocytosis New nodule Odds ratio pathology Patient Prevalence pulse reported syndrome the disease univariable [DOI] 10.1111/myc.13485 PMC 바로가기
Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in miceArticle Published on 2022-11-012022-11-15 Journal: Inflammation research : official journal of the Eu [Category] 유전자 메커니즘, 진단, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome alleviate Analysis Anti-inflammatory anti-inflammatory property anti-inflammatory response ARDS CFZ Clofazimine coronavirus disease COVID-19 Critical decrease disease Diseases distress down-regulate histological change hyperimmune response IL-1β immune IMPROVE increasingly Infectious disease Inflammatory information inhibit involved lipopolysaccharide LPS lung Lung injury Macrophage macrophages mechanism mice Molecular biology pathway pharmacological mechanism potential molecular profile proliferation protective effect Protein protein expression Proteomic analysis proteomics Pulmonary edema Quantitative Signal transduction Signaling significantly survival rate syndrome therapeutic strategy TNF-α [DOI] 10.1007/s00011-022-01623-w PMC 바로가기
Nitazoxanide and COVID-19: A reviewArticle Published on 2022-11-012022-11-15 Journal: Molecular biology reports [Category] SARS, 치료제, [키워드] Activation acute lung injury acute respiratory distress acute respiratory distress syndrome addition Anti-inflammatory anti-parasitic drug anti-SARS-CoV-2 Antiviral antiviral activity antiviral property ARDS autophagic cause cell death clinical trial Coronavirus disease 2019 COVID-19 Cytokine storm Cytokines distress drug effective finding IFN immunological in silico in vitro study Infection inflammatory disorders inflammatory reaction inhibit Innate immunity interferon lung mammalian mitigate Multi-organ damage nitazoxanide oxidative stress pathogenesis of SARS-CoV-2 pro-inflammatory cytokines Prospective Study Protozoa Rapamycin reduce Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 infections severe cases syndrome therapy Treatment triggered viral infections Viral pneumonia [DOI] 10.1007/s11033-022-07822-2 PMC 바로가기
Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulinArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] abrogation Activation acute respiratory distress addition Alter ARDS cell-free DNA circulation Clinical treatment Corticosteroids Course COVID-19 COVID-19 patient Critically ill Dexamethasone dose-dependent elevated Ex vivo Factor functions healthy controls healthy donor healthy donors IL-8 inflammatory pathway Intravenous immunoglobulin Intravenous immunoglobulin (IVIG) lack Level Lung injury lung parenchyma modulate NET NETosis NETs neutrophil Neutrophil elastase Neutrophil extracellular trap neutrophil function Neutrophils not affect oxidative oxidative burst Patient Peripheral blood phagocytosis PMA pro-inflammatory function Proteins reactive oxygen specy reduced reduction severity syndrome targeting therapeutic therapeutic agent Tocilizumab treated Treatment were assessed while with COVID-19 [DOI] 10.3389/fimmu.2022.993720 PMC 바로가기
Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels-A pilot study in healthy individuals with implications for COVID-19 and ARDSArticle Published on 2022-10-172022-11-15 Journal: PLoS ONE [Category] 치료제, [키워드] ACE2 ACE2 expression acute respiratory distress alarmin Analysis angiotensin-converting enzyme 2 Antiviral ARDS ARDS patient baseline baseline levels blood sample cause cellular change collected coronavirus disease COVID-19 enrolled enzyme-linked immunosorbent exhibit expression glycyrrhizin healthy individual healthy volunteer HMGB1 hospitalised COVID-19 patient hospitalised patient immunomodulatory property implication in healthy individual in healthy individuals individual individuals liquorice material Mild modulate Non-COVID-19 not different Patient patients pilot study Plasma HMGB1 Potential treatment pro-inflammatory receptor ACE2 reduced reduction in Respiratory disease significantly significantly higher syndrome viral entry were measured with mild disease [DOI] 10.1371/journal.pone.0275181 PMC 바로가기
Development of Single-Cell Transcriptomics and Its Application in COVID-19Article Published on 2022-10-162022-11-16 Journal: Viruses [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory distress acute respiratory syndrome application ARDS asymptomatic infection basic reproduction number caused claimed clinical manifestation clinical manifestations component coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 research Critical death development differentially expressed gene examined Health immune immune response IMPROVE individual cells mutate offered over physiological resulting SARS-CoV-2 Sequencing single-cell Single-cell transcriptomics syndrome transcriptomics Treatment variety [DOI] 10.3390/v14102271 PMC 바로가기
Natural and Semi-Synthetic Flavonoid Anti-SARS-CoV-2 Agents for the Treatment of Long COVID-19 Disease and Neurodegenerative Disorders of Cognitive DeclineReview Published on 2022-10-092023-07-11 Journal: Frontiers in bioscience (Elite edition) [Category] COVID19(2023년), [키워드] Alzheimer's disease Anti-inflammatory Anti-oxidant anti-viral phytochemicals ARDS chalcones cognition and memory flavones long COVID disease Neuroinflammation neuroprotection Nrf2 Parkinson's Disease SARS-CoV-2 [DOI] 10.31083/j.fbe1404027 [Article Type] Review