Colchicine – Page 8 – Communicable Diseases Research

Efficacy of COVID-19 Treatments: A Bayesian Network Meta-Analysis of Randomized Controlled Trials

COVID-19 치료의 효능 : 무작위 대조 시험의 베이지안 네트워크 메타 분석

Meta-Analysis

Published on 2021-09-282022-08-31
Journal: Frontiers in Public Health [Category] meta-analysis, SARS, 임상,

Clinical outcome of patients with COVID-19 Pneumonia treated with corticosteroids and colchicine in Colombia

Research

Published on 2021-09-142022-10-28
Journal: Annals of Clinical Microbiology and Antimicrobials [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome addition adjust alveolar analyzed antiviral therapy association Berlin protocol cause chain changed Chest computed tomography clinical clinical manifestation Colchicine Complication complications Contagion coronavirus coronavirus 2 Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 cross death develop drug effort evaluate evaluate the effect fraction ground glass hospital Hospitalization information initial institutional protocol less management management protocol material measure Mortality outcome oxygen PaFi Patient patients with COVID-19 placebo-controlled study Pneumonia Prevent Protective public health measure reaction receive required Result RT-PCR SARS-CoV-2 SARS-CoV2 statistical suggested supplemental oxygen the patient therapy treated Treatment utility Vaccine variable while
[DOI] 10.1186/s12941-021-00460-9 PMC 바로가기 [Article Type] Research

The effectiveness of early colchicine administration in patients over 60 years old with high risk of developing severe pulmonary complications associated with coronavirus pneumonia SARS-CoV-2 (COVID-19): study protocol for an investigator-driven randomized controlled clinical trial in primary health care—COLCHICOVID study

코로나바이러스 폐렴 SARS-CoV-2(COVID-19)와 관련된 중증 폐합병증 발병 위험이 높은 60세 이상의 환자에서 조기 콜히친 투여의 효과: 1차 의료에서 연구자 주도 무작위 대조 임상 시험을 위한 연구 프로토콜 —콜치코비드 연구

Study Protocol

Published on 2021-09-062022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] Activation addition administration age Anti-inflammatory Care clinical effectiveness Clinical practice Clinical research clinical trial clinical trials Coagulation Colchicine collapse Comorbidities Complication Controlled clinical trial coronavirus Coronavirus pneumonia COVID pneumonia COVID-19 COVID-19 infection COVID-19 pandemic death demonstration early administration early treatment Effectiveness Efficacy evaluate Evidence generate Health Health crisis health system high risk hospital Hospital admission Infection inhibitory effect lethality level of care mitigate Mortality multicenter No hospitalized Open-label pandemic parallel group Pathologies Patient pharmacological Pneumonia Pragmatic Prevent primary care Primary Health Care profile Prophylaxis pulmonary complication pulmonary complications Randomized reduce reducing Research SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection serious complication Study protocol successive wave successive waves susceptible target population Treatment Trial registration Viral viral replication Volume vulnerable patients with COVID-19
[DOI] 10.1186/s13063-021-05544-7 PMC 바로가기 [Article Type] Study Protocol

Repurposing Colchicine in Treating Patients with COVID-19: A Systematic Review and Meta-Analysis

Systematic Review

Published on 2021-08-232022-10-29
Journal: International Review of Cell and Molecular Biology [Category] COVID-19,

[키워드] 95% confidence interval Analysis analyzed anti-inflammatory property applied benefit caused Colchicine colchicine treatment Coronavirus disease 2019 COVID-19 COVID-19 patient drug Effect enrolled evaluated Health immunomodulation male mechanical ventilation Meta-analysis Mild Mortality not significantly different Novel coronavirus Odds ratio Pathways patients with COVID-19 potential benefit randomized controlled study Randomized controlled trial Randomized controlled trials repurposing required review risk SARS-CoV-2 searched Side effect significantly lower square statistically significant difference subgroup analysis systematic review treat treating
[DOI] 10.3390/life11080864 PMC 바로가기 [Article Type] Systematic Review

Hemophagocytic syndrome secondary to SARS-Cov-2 infection: a case report

Case Report

Published on 2021-08-132022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS,

Perimyocarditis following first dose of the mRNA-1273 SARS-CoV-2 (Moderna) vaccine in a healthy young male: a case report

Case Report

Published on 2021-08-042022-10-27
Journal: BMC Public Health [Category] COVID-19,

Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial

Covid-19 (Colcorona)를 가진 지역 사회 치료 환자를위한 콜히친 : 3 단계, 무작위, 이중 맹검, 적응 형, 위약 대조, 다중 센터 시험

Clinical Trial

Published on 2021-08-012022-08-13
Journal: The Lancet. Respiratory Medicine [Category] MERS, SARS, 임상,

[키워드] 1:1 absence adaptive adverse event allocation sequence Analysis anti-inflammatory agent assigned automated automated interactive web-response system benefit block size block sizes blocking schema Brazil Canada clinical criteria Colchicine colchicine group COLCORONA trial community-treated patient community-treated patients complications Composite computer-generated coronary disease COVID-19 COVID-19 complication COVID-19 complications COVID-19-related clinical event COVID-19-related clinical events COVID-19-related death death diagnosed diagnostic test diarrhoea double-blind double-blinded eligible enrolled excessive inflammation family finding foundation funding Gout Government Greece heart high-risk characteristic hospital Hospital admission intention-to-treat principle interactive web-response system IQR mandatory diagnostic test masked randomisation matching placebo median age Medicine Melinda Gate Melinda Gates Montreal Heart Institute multicentre occurred Odds ratio oral anti-inflammatory medication orally administered colchicine orally administered therapies orally administered therapy Participants Patient patients PCR testing PCR-confirmed PCR-confirmed COVID-19 PCR-positive community-treated patient PCR-positive community-treated patients per day Pericarditis Phase 3 Placebo placebo group placebo-controlled Pneumonia Prevent primary efficacy endpoint primary endpoint randomisation list randomised Randomly receive Registered Replication reported risk Safe School Serious Adverse Events Sophie South Africa Spain statistically significant the placebo group the primary endpoint treated Trial trial enrolment unmasked biostatistician USA Vital vital status was done with COVID-19
[DOI] 10.1016/S2213-2600(21)00222-8 PMC 바로가기 [Article Type] Clinical Trial

Colchicine use might be associated with lower mortality in COVID‐19 patients: A meta‐analysis

Research Article

Published on 2021-07-182022-10-31
Journal: European Journal of Clinical Investigation [Category] COVID-19, SARS,

Complex analysis of the personalized pharmacotherapy in the management of COVID-19 patients and suggestions for applications of predictive, preventive, and personalized medicine attitude

Research

Published on 2021-07-162022-10-31
Journal: The EPMA Journal [Category] COVID-19,

[키워드] all ethnic groups alpha-2b analysed Analysis antiviral agent approach Biomarker calculated ceftriaxone Characteristics Chloroquine clinical Clinical practice clinical trial Colchicine collected Comorbidities comprehensive analysis Coronavirus disease 2019 COVID-19 COVID-19 patient daclatasvir defined Dexamethasone drug Drug efficacy Drug score drug therapy Drug-to-drug interaction drugs ethnic group Ethnicity-based differences evaluate facilitate Frequency functional Future healthcare Gene score generate genetic difference genetic differences genetic test HCQ highest human immunoglobulin human immunoglobulin G Hydroxychloroquine immune regulator indicated Individual outcomes individuals interferon interferon alpha-2b Interferon beta-1a levofloxacin Lopinavir losartan management molecular mechanisms Optimal medication patients with comorbidity performed Personalized medicine personalized treatment pharmacogenetic pharmacogenetics pharmacogenomics Predictive Predictive preventive personalized medicine (PPPM/3 PM) Prednisone Remdesivir reported Result ribavirin Ritonavir significantly sofosbuvir suggested supplementary material the patient translation Treatment Trial Variation variations Zinc
[DOI] 10.1007/s13167-021-00247-0 PMC 바로가기 [Article Type] Research

The effectiveness of Colchicine as an anti-inflammatory drug in the treatment of coronavirus disease 2019: Meta-analysis

Letter to the Editor

Published on 2021-07-102023-06-18
Journal: International journal of immunopathology and pharm [Category] MERS,

[키워드] Anti-inflammatory Colchicine COVID-19 hospitalization time mortality rate
[DOI] 10.1177/20587384211031763 PMC 바로가기 [Article Type] Letter to the Editor