D614G – Page 8 – Communicable Diseases Research

Vaccine-Induced Antibody Responses against SARS-CoV-2 Variants-Of-Concern Six Months after the BNT162b2 COVID-19 mRNA Vaccination

BNT162b2 COVID-19 mRNA 백신 접종 후 6개월 후의 SARS-CoV-2 변이체에 대한 백신 유도 항체 반응

Article

Published on 2022-04-272022-09-11
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Alpha anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody antibody levels Beta BNT162b2 BNT162b2 vaccine booster dose booster doses collected coronavirus COVID-19 COVID-19 disease COVID-19 mRNA vaccine COVID-19 mRNA vaccines D614G decrease Delta delta variant detectable dose effective Efficacy Eta fold Health care Health care worker immune evasion immune responses Lineage Month mRNA mRNA vaccine mRNA vaccines neutralization neutralize neutralized Neutralizing Neutralizing antibodies new virus of BNT162b2 persistence postvaccination raised receiving reduced reduction respiratory response responses SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 variant sera severe acute respiratory syndrome Coronavirus severe COVID-19 disease specific antibodies Transmissibility vaccination Vaccination strategies Vaccination strategy Vaccine vaccine efficacy vaccinees Vaccines variant variants
[DOI] 10.1128/spectrum.02252-21 PMC 바로가기 [Article Type] Article

mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

mRNA-1273 및 Ad26.COV2.S 백신은 SARS-CoV-2의 B.1.621 변이체로부터 보호합니다.

Clinical and Translational Article

Published on 2022-04-152022-09-14
Journal: Med (New York, N.Y.) [Category] COVID19(2023년), MERS, SARS, 변종, 비임상, 진단,

[키워드] in vivo vaccine efficacy studies Abstract ACE2 acute respiratory syndrome Ad26.COV2.S Ad26.COV2.S vaccine adenoviral-vectored vaccine AMED animal models B.1.621 center Context coronavirus D614G D950N development disease E484K Efficacy evaluated finding funding greater transmissibility hamster hamsters High dose Immunity immunization induce Infectious disease Infrastructure Innovation Japan Johnson & Johnson Lung infection Lung pathology mice Moderna mRNA vaccine mouse mRNA-1273 mRNA-1273 vaccine N501Y Neutralizing antibodies neutralizing antibody New NIAID NIH omicron P681H Program PROTECT reduced response SARS-CoV-2 SARS-CoV-2 strain Serum neutralizing antibody spike mutation supported Syrian hamster transgenic mice Vaccine variant variant of SARS-CoV-2 variants of SARS-CoV-2 viral variant virus WA1/2020 weight loss
[DOI] 10.1016/j.medj.2022.03.009 PMC 바로가기 [Article Type] Clinical and Translational Article

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

Article

Published on 2022-04-082022-10-04
Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술,

Whole-genome analysis of SARS-CoV-2 in a 2020 infection cluster in a nursing home of Southern Italy

남부 이탈리아 요양원의 2020년 감염 클러스터에서 SARS-CoV-2의 전체 게놈 분석

Article

Published on 2022-04-012022-09-12
Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), MERS, SARS, 진단,

Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions

SARS-CoV-2의 오미크론 변이체(B.1.1.529): 게놈, S-당단백질 및 항체 결합 영역의 돌연변이 이해

Article

Published on 2022-04-012022-09-11
Journal: GeroScience [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2

인간 진입 수용체 DPP4 및 ACE2를 표적으로 하는 SARS-CoV-2 스파이크 당단백질에 대한 이중특이성 항체 설계

Article

Published on 2022-04-012022-09-11
Journal: Human immunology [Category] COVID19(2023년), SARS, 바이오마커, 진단,

[키워드] ACE2 Anti-viral antibody binding affinity Bispecific Antibody (BsAb) block China cleavage condition COVID-19 CrossMAb D614G disease DPP4 entry receptor epithelial cells Fc region global pandemic glycoprotein hACE2 hACE2 receptor heavy chain Host in-silico Infection KIH light chain linker lung alveolar lung alveolar epithelial cells modifications Molecular docking study mutated peptide performed Prevent receptor receptor engagement receptors regdanvimab Research SARS-CoV-2 SARS-CoV-2 spike glycoprotein spike spike glycoprotein Spike protein therapeutic target therapy Viral viral entry viral spike viral spike protein virus Wuhan
[DOI] 10.1016/j.humimm.2022.01.004 PMC 바로가기 [Article Type] Article

Differential neutralizing antibody responses elicited by CoronaVac and BNT162b2 against SARS-CoV-2 Lambda in Chile

Research

Published on 2022-04-012022-10-05
Journal: Nature Microbiology [Category] COVID19(2023년), SARS, 변종,

[키워드] 1.26 Analysis antibody antigenic BNT162b2 Comparative convalescent plasma CoronaVac D614G Delta delta variant dominant Efficacy elicit elicited Faculty of Medicine First wave Gamma healthcare worker HEK293T-ACE2 cells Immune escape inactivated individual Lambda Local Messenger RNA Mutation N-terminal domain neutralization neutralization capacity neutralize neutralizing antibody Neutralizing antibody response neutralizing antibody titre pseudotyped Pseudotyped virus reduced replication SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants South Structure the receptor-binding domain the spike protein vaccination Vaccine variant variants Vero-E6 cell virus was reduced Wuhan-Hu-1
[DOI] 10.1038/s41564-022-01092-1 [Article Type] Research

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

SARS-CoV-2 mRNA 백신 접종에 의해 유발된 중화 항체 반응은 시간이 지남에 따라 약해지고 돌발성 감염에 의해 강화됩니다

Article

Published on 2022-03-232022-09-11
Journal: Science Translational Medicine [Category] MERS, SARS, 변종, 진단, 치료기술,

[키워드] addition Alpha Antibody Response Antibody titer Antibody titers B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta BNT162b2 Booster vaccine Breakthrough infection breakthrough infections collected D614G debate declined Delta dependent on dose doses Efficacy elicited examined exhibited first vaccination FIVE HCW HCWs Health care Health care worker health care workers Infection Most patients mRNA mRNA vaccination mRNA vaccine mRNA vaccines Neutralizing antibodies neutralizing antibody Neutralizing antibody response Neutralizing antibody titer neutralizing antibody titers omicron Patient Protein pseudovirus pseudoviruses recipient recipients SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccines SARS-CoV-2 variant SARS-CoV-2 variants second vaccination serum sample serum samples Spike protein the spike protein vaccination vaccine responses Vaccine-induced immunity variant variant spike variants
[DOI] 10.1126/scitranslmed.abn8057 PMC 바로가기 [Article Type] Article

In vitro evaluation of therapeutic antibodies against a SARS-CoV-2 Omicron B.1.1.529 isolate

SARS-CoV-2 Omicron B.1.1.529 분리주에 대한 치료 항체의 시험관 내 평가

Article

Published on 2022-03-182022-09-11
Journal: Scientific Reports [Category] SARS, 변종, 진단,

SARS-CoV-2 spike E156G/Δ157-158 mutations contribute to increased infectivity and immune escape

SARS-CoV-2 스파이크 E156G/Δ157-158 돌연변이는 증가된 감염성과 면역 탈출에 기여합니다

Article

Published on 2022-03-162022-09-11
Journal: Life Science Alliance [Category] COVID19(2023년), SARS, 변종,