Relationship Between Serum Severe Acute Respiratory Syndrome Coronavirus 2 Nucleic Acid and Organ Damage in Coronavirus 2019 Patients: A Cohort Study코로나바이러스 2019 환자의 혈청 중증 급성 호흡기 증후군 코로나바이러스 2 핵산과 장기 손상 간의 관계: 코호트 연구Article Published on 2021-07-012022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] abnormality acid acute respiratory syndrome acute respiratory syndrome coronavirus affected Analysis analyzed association Blood urea nitrogen cardiac damage Coagulopathy collected Comorbidities Computed tomography coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 D-dimer damage demographic demographic data Evidence higher risk highest hypersensitive in-hospital mortality information Laboratory laboratory biomarker laboratory-confirmed Laboratory-confirmed COVID-19 Lactate lactate dehydrogenase mortality rate Multiple organ damage multiple organs nitrogen nucleic acid organ damage outcome Patient Protein provided radiological relationship renal damage respiratory Respiratory failure RNA RNAemia SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 RNA serum serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher Spread Support symptom onset tested throat swab throat swabs total protein troponin I university urea Viral load Wuhan [DOI] 10.1093/cid/ciaa1085 PMC 바로가기 [Article Type] Article
ACE2 Down-Regulation May Act as a Transient Molecular Disease Causing RAAS Dysregulation and Tissue Damage in the Microcirculatory Environment Among COVID-19 PatientsACE2 하향 조절은 COVID-19 환자의 미세 순환 환경에서 RAAS 조절 장애 및 조직 손상을 유발하는 일시적인 분자 질환으로 작용할 수 있음Review Published on 2021-07-012022-09-11 Journal: The American journal of pathology [Category] 유전자 메커니즘, 진단, [키워드] ACE2 Act acute respiratory syndrome acute respiratory syndrome coronavirus aldosterone angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 article Brain cause causing change changes in coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 damage disease Environment etiologic agent heart Infection Injury kidney Lungs manifestation mechanism molecular Molecular Disease multiform negative regulation offer organ organ systems pandemic pathophysiological provide RAAS Renin renin-angiotensin-aldosterone system respiratory responsible severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Transient Treatment variety vasculature [DOI] 10.1016/j.ajpath.2021.04.010 PMC 바로가기 [Article Type] Review
Long-Term Pulmonary Damage From SARS-CoV-2 in an Infant With Brief Unexplained Resolved Events: A Case ReportMedicine Published on 2021-06-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome administration age breathing Chest computed tomography coronavirus COVID-19 COVID-19 infection damage died distress Fever FIVE Follow-up healthy Hospital admission Hospitalized Infant infected with SARS-CoV-2 Inhaled lack lung involvement mild respiratory mother Nasopharyngeal swab Newborn over oxygen Pneumonia positive pulmonary pulmonary complication pulmonary involvement report required resolved respiratory symptom SARS-CoV-2 SARS-CoV-2 pneumonia severe pneumonia sleep disorders tested weakness [DOI] 10.3389/fmed.2021.646837 PMC 바로가기 [Article Type] Medicine
A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?Covid-19 Malady의 임상 및 기계적 병리 생리 학적 측면에 대한 포괄적 인 검토 : 우리는 얼마나 멀리 왔습니까?Review Published on 2021-06-072022-09-10 Journal: Virology Journal [Category] MERS, 치료제, [키워드] ACE2 receptors affecting analyzed approved articles Case report case reports Case series clinical presentation comorbid disease comorbid diseases Comorbidities Comorbidity contributed coronavirus coronavirus disease COVID-19 current cytokine cytokine production damage determine disease manifestation disease severity Effect Entry mechanism host cell host cells immune response include Inflammation irreversible damage lead long term Manifestations mechanism Mortality observational studies organ damage organ system organ systems outbreak pandemic pathology pathophysiologic pathophysiological Pathways patients penetration Prevalence recorded Research retrieved reveal short term Signs and symptoms SPSS Symptoms systemic inflammation Treatment underlying disease Vaccine Viral Viral proteins [DOI] 10.1186/s12985-021-01578-0 PMC 바로가기 [Article Type] Review
Enhanced IL-6 and IL-12B Gene Expression After SARS-CoV-2 Infection in Leprosy Patients May Increase the Risk of Neural DamageSARS-CoV-2 감염 후 나병 환자에서 IL-6 및 IL-12B 유전자 발현 증가가 신경 손상 위험을 증가시킬 수 있습니다.Articles Published on 2021-06-052022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, 한센병, [키워드] acute respiratory syndrome analyzed Brazil Control controls coronavirus coronavirus disease CoV COVID-19 epidemic Cytokine storm syndrome damage diagnosed with COVID-19 enhanced expert expression Frequency genes encoding IL-10 IL-12B IL-6 IL-8 increase leprosy median mononuclear cells Mycobacterium leprae Neural not significant Patient Peripheral blood progression proinflammatory SARS-CoV-2 tumor necrosis factor-α [DOI] 10.4269/ajtmh.21-0034 PMC 바로가기 [Article Type] Articles
Heterogeneity in Regional Damage Detected by Neuroimaging and Neuropathological Studies in Older Adults With COVID-19: A Cognitive-Neuroscience Systematic Review to Inform the Long-Term Impact of the Virus on Neurocognitive TrajectoriesNeuroscience Published on 2021-06-032022-10-31 Journal: Frontiers in Aging Neuroscience [Category] COVID-19, [키워드] added Adults Affect Ageing behavioural Brain Cardiopulmonary Case series cellular damage cognitive consequence Consequences COVID-19 COVID-19 infection damage data-driven database develop DNA dysfunction Encephalitis Encephalopathy events Evolution exacerbated functional Health heterogeneity hospitalisation hospitalised patient identify Impact indicate Infection Inflammation involved manuscript mechanism Mental neurocognitive Neuroimaging neurological Neurological symptom Neuropathology Older older patient olfactory Other outcome output patients with COVID-19 Perspective Premature Region Regional reported review screened searched selected severe symptom stroke Support systematic review the disease virus Web of Science with COVID-19 [DOI] 10.3389/fnagi.2021.646908 PMC 바로가기 [Article Type] Neuroscience
Is the First of the Two Born Saved? A Rare and Dramatic Case of Double Placental Damage from SARS-CoV-2Case Report Published on 2021-05-262022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] affected amenorrhea Autopsy coronavirus COVID-19 damage described dichorionic died fetus knowledge mechanism Obstetric pandemic Placenta placental responsible SARS-CoV-2 [DOI] 10.3390/v13060995 PMC 바로가기 [Article Type] Case Report
SARS-CoV-2 Disinfection of Air and Surface Contamination by TiO 2 Photocatalyst-Mediated Damage to Viral Morphology, RNA, and ProteinArticle Published on 2021-05-202022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] absence adverse effect aerosol Aerosols Compound contaminated surface COVID-19 damage decrease disease-causing Disinfection Effect effective for disinfection Genome global pandemic Health Human infectious agents Radiation reduced RNA RNA damage RT-qPCR SARS-CoV-2 SARS-CoV-2 inactivation Spread surface TiO2 photocatalyst toxicities transmission electron microscopy transmitted Treatment ultraviolet C viral morphology disruption Viral protein viral protein damage virion virus [DOI] 10.3390/v13050942 PMC 바로가기 [Article Type] Article
Severe acute respiratory Syndrome-Coronavirus-2: Can it be detected in the retina?중증급성호흡기증후군-코로나바이러스-2: 망막에서도 검출 가능한가요?Research Article Published on 2021-05-132022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] Analysis Can carried COVID-19 COVID-19 patients damage Deceased diagnosis of SARS-CoV-2 donors Effect eosin eye fluids hematoxylin Hematoxylin and eosin highest histopathological histopathological examination Histopathological examinations Histopathology humans Infection Inflammation investigated measure Morphological morphologically ocular organ performed Personal protective equipment Pharyngeal swab PPE preparation qRT-PCR Quantitative Result Retina SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA significant level tissue tissues vasculature vessel Viral Viral RNA vitreous vitreous fluid [DOI] 10.1371/journal.pone.0251682 PMC 바로가기 [Article Type] Research Article
Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era코로나19 시대의 줄기세포 치료제와 체세포 핵이식 복제의 장점Review Published on 2021-05-122022-09-12 Journal: Stem Cell Research & Therapy [Category] SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome Anti-inflammatory antivirals ARDS being benefit Bio-pharming boost caused Cell cell type Cell-based therapy cellular Clinical studies cloned COVID-19 COVID-19 patient COVID-19 patients damage dependence develop Drug testing Embryo embryonic embryos generate Genome reprogramming Health health emergency immunomodulatory effect immunomodulatory effects Interaction mesenchymal stem cell Mesenchymal stem cells MSC MSCs nuclear organ Organoid organoids potential benefit potential benefits prominence regenerative regenerative medicine Research respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-COV-2 infection SCNT somatic cell STEM stem cell stem cells structures syndrome therapeutic Therapies therapy transfer transgenic treat unique Vaccinations Vascular [DOI] 10.1186/s13287-021-02334-5 PMC 바로가기 [Article Type] Review