Underlying Mechanisms and Candidate Drugs for COVID-19 Based on the Connectivity Map Database
Genetics
[키워드] ACE2
ACE2 expression
acute respiratory syndrome
Analysis
analyzed
angiotensin-converting enzyme 2
antiviral drug
BALF
BALF cell
Bronchoalveolar lavage fluid
candidate
candidate drug
Cell
cells
clinical trial
co-expressed
connectivity
coronavirus
coronavirus disease
Coronavirus disease 2019
correlated
COVID-19
database
DEGs
differentially expressed gene
down-regulated gene
drug
effective
expression
functional enrichment
functions
gene cluster
Genes
healthy
homologous
identify
immune defense
immune dysfunction
immune response
indicated
lung
Map
mechanism
mRNA translation
patients
patients with COVID-19
performed
positively correlated
potential drugs
public health crisis
receptor
reduce
reflected
regulatory agency
Result
RNA
SARS-CoV
SARS-CoV infection
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
synaptic
transcriptome profile
Transmission
treat
Treatment
underlying mechanisms
up-regulated
Vaccine
viral proliferation
[DOI] 10.3389/fgene.2020.558557 PMC 바로가기 [Article Type] Genetics
[DOI] 10.3389/fgene.2020.558557 PMC 바로가기 [Article Type] Genetics