escape – Page 8 – Communicable Diseases Research

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera

Article

Published on 2021-04-292022-10-31
Journal: Cell [Category] COVID-19, MERS, SARS,

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

회복기 및 백신 혈청에 의한 SARS-CoV-2 B.1.1.7 변이체의 중화 감소

Article

Published on 2021-04-152022-09-11
Journal: Cell [Category] MERS, SARS, 변종, 진단,

[키워드] Abstract ACE2 ACE2 binding Amino acid amino acid change Analysis antibody Antibody Response Antibody responses appearance B.1.1.7 B.1.1.7 variant binding affinity can not caused Contact convalescent death dominant elicited ENhance escape evade generate IGHV3-53 Kent monoclonal antibodies monoclonal antibody mutant virus mutant viruses N501Y natural antibody natural infection neutralization neutralize neutralized original original form pandemic parental reduced residue responses responses against SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-COV-2 infection sera Transmission vaccination Vaccine Vaccines variant virus virus replication Virus spike viruses widespread
[DOI] 10.1016/j.cell.2021.02.033 PMC 바로가기 [Article Type] Article

Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma

Research

Published on 2021-03-292022-10-05
Journal: Nature [Category] SARS, 변종, 진단,

Impact of a Serious Game (Escape COVID-19) on the Intention to Change COVID-19 Control Practices Among Employees of Long-term Care Facilities: Web-Based Randomized Controlled Trial

Randomized Controlled Trial

Published on 2021-03-252022-10-04
Journal: Journal of Medical Internet Research [Category] SARS, 임상,

[키워드] 95% CI Affect analyzed asked attrition baseline Care change changes in Complication Control control group Controlled COVID-19 COVID-19 IPC guidelines death demographic data determine dissemination domain Effect elderly employee equipment escape facilitated Factor game Gamification Health authority Health care worker high risk Identifier Impact IMPROVE induce Infection prevention information Intention knowledge limit logistic regression model long-term care facilities MOST nursing homes objective Odds ratio outcome participant Participants Practice Primary outcome Probability proportion Protective questionnaire random effect Randomized controlled trial Randomly report resources Result SARS-CoV-2 SARS-COV-2 infection second set secondary serious game Switzerland the epidemic took place Transmission triple-blind Viral transmission
[DOI] 10.2196/27443 PMC 바로가기 [Article Type] Randomized Controlled Trial

SARS-CoV-2 Entry Related Viral and Host Genetic Variations: Implications on COVID-19 Severity, Immune Escape, and Infectivity

SARS-CoV-2 진입 관련 바이러스 및 숙주 유전자 변이: COVID-19 심각도, 면역 탈출 및 감염성에 미치는 영향

Review

Published on 2021-03-172022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 변종,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus Adhesion Molecule Affect angiotensin antiviral drugs binding Cell contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical determine driving drug enzyme escape Evolution genetic diversity genetic risk Genetic variation Genetic variations Genome geographical regions glycoprotein high risk Host host protein human population human populations immune Immune escape Impact in viral Infectivity integrin intercellular intercellular adhesion molecule Mutation Pathogenesis Pathogens Population Positive selection Precision protease Protein Receptor binding domain Research respiratory S glycoprotein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 S glycoprotein SARS-CoV-2 variant SARS-CoV-2 variants Serine serine 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity spike glycoprotein susceptibility the cell the SARS-CoV-2 TMPRSS2 transmembrane transmembrane protease serine 2 Transmissibility Transmission variants Variation Viral viral evolution viral S virus virus transmissibility vital role vital roles
[DOI] 10.3390/ijms22063060 PMC 바로가기 [Article Type] Review

Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck

집 고양이에서 SARS-CoV-2의 전파는 좁은 병목 현상을 초래합니다

Research Article

Published on 2021-02-262022-08-13
Journal: PLoS Pathogens [Category] MERS, 변종, 유전자 메커니즘, 진단,

[키워드] accelerated adaptive Amino acid amino acid position antigenic evolution arise bottleneck cats defined distribution escape event Evolution fixation fixed followed by Genetic genetic drift Genetic variation genomic H655Y Host hosts Human human monoclonal antibodies Human monoclonal antibody identify Infection intermediate frequency involved landscape mammalian mechanism model systems new infections new SARS-CoV-2 notable persist Positive selection reveal RNA virus SARS-CoV-2 SARS-CoV-2 consensus sequence SARS-CoV-2 consensus sequences SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus SARS-CoV-2 viruses scrutiny selected shown species spike Surveillance Therapeutics this system Transmission transmitted undergo Vaccine variant viruses
[DOI] 10.1371/journal.ppat.1009373 PMC 바로가기 [Article Type] Research Article

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

SARS-CoV-2에 대한 조작된 미끼 수용체는 단백질 S 서열 변이체에 광범위하게 결합합니다

Research Article

Published on 2021-02-172022-08-13
Journal: Science Advances [Category] Biochemistry, 변종,

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

Article

Published on 2021-01-132022-10-31
Journal: Cell Host & Microbe [Category] COVID-19, Fulltext, SARS,

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

SARS-CoV-2 스파이크 단백질 변이체에 의한 중화 항체로부터의 탈출

Research Article

Published on 2020-10-282022-09-10
Journal: eLife [Category] MERS, SARS, 변종, 진단,

[키워드] activate addressed Administered Analysis anti-SARS-CoV-2 antibodies antibody antibody combination antibody-based therapies antibody-based therapy Blood blood plasma cause Cell cells changed chimeric circulating Combination convalescent plasma coronavirus COVID-19 COVID19 creating effective vaccine Effective vaccines Effectiveness effort elicited eLife Epitopes escape evade Frequency functional Genome Health HIV host cells Human human cells human population human populations immune immune response immune system in some individual infect Infection Influenza kill Laboratory limit low frequencies maintain monoclonal antibodies monoclonal antibody mutant mutant virus mutate mutated Mutation N-terminal domain natural infection neutralize Neutralizing antibodies neutralizing antibody neutralizing epitopes New coronavirus Patient Population populations Prevent produced Prophylactic Proteins question RBD Receptor-binding domain Recovered COVID-19 patients reporter Research SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 spike protein SARS-CoV-2 variant selected Sequencing Spike protein Spike proteins Structure structures target the antibody the disease the receptor-binding domain the SARS-CoV-2 the spike protein the strongest therapeutic Therapies treated Trigger vaccination Vaccine Vaccines variant Viral protein Viral proteins virus virus mutation virus particle virus particles viruses VSV were infected
[DOI] 10.7554/eLife.61312 PMC 바로가기 [Article Type] Research Article

Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015

Research

Published on 2019-06-012022-10-31
Journal: Emerging Infectious Diseases [Category] Coronavirus,

[키워드] addition affected amplified analyzed Antibody neutralization Antigen association CD26 collected emergence Epidemiology escape events Fever genetic information immunized initiated MERS-CoV mice Middle East Middle East respiratory syndrome Coronavirus mutant mutant virus neutralization Neutralizing activity outbreak patients receptor reduced reported respiratory respiratory infections respiratory syndrome coronavirus sequence sequential emergence serum sample South Korea spike spike mutation Spread superspreading superspreading events syndrome systemically virulence virus viruses wild-type zoonoses
[DOI] 10.3201/eid2506.181722 PMC 바로가기 [Article Type] Research