Immunodeficient patient experience of emergency switch from intravenous to rapid push subcutaneous immunoglobulin replacement therapy during coronavirus disease 2019 shieldingArticle Published on 2022-12-012022-11-15 Journal: Current opinion in allergy and clinical immunology [Category] 진단, [키워드] administration Anxiety assessment collected Concentration coronavirus disease COVID-19 greater high risk IgG IgG level immunodeficient patient Immunoglobulin immunoglobulin replacement therapy In-hospital Infection intravenous Intravenous immunoglobulin IVIG Laboratory Measures mitigate outcome Patient receiving recent reported risk severe coronavirus disease shielding subcutaneously Subjective transitioned [DOI] 10.1097/ACI.0000000000000864 PMC 바로가기
COVID-19 breakthrough infections and humoral immune response among BNT162b2 vaccinated healthcare workers in Malaysia말레이시아에서 BNT162b2 백신을 접종한 의료 종사자의 COVID-19 획기적인 감염 및 체액성 면역 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] 95% CI affected age Anti-S1 Anti-spike antibody Antibody Response antibody titres association Asymptomatic Asymptomatic individuals blood sample Blood samples BNT162b2 booster vaccination breakthrough Breakthrough infection breakthrough infections collected COVID-19 COVID-19 infection delta variant detectable domain geometric mean geometric mean titre GMT HCWs healthcare healthcare worker Healthcare workers humoral humoral immune response Humoral immunity IgG IgG assay individual individuals Infection investigated Malaysia not different notable outcome Participants prospective cohort study Protein response significantly significantly higher Support symptomatic the antibody response vaccination Vaccine vaccine doses waned was measured [DOI] 10.1080/22221751.2022.2065936 PMC 바로가기 [Article Type] Article
Ultrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversionArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] addition antibodies Antibody Response approach AUC collected COVID-19 COVID-19 patient diagnostic diagnostics Donor Extreme early-stage seroconversion faster flow cytometry healthy IgG IgG and IgM IgG/IgM antibodies IgM immunoassay immunoassays immunological inactivated nucleic acid nucleic acids other diseases pathogen-specific Patient peptide platform probe Protein RBD reveal Rhesus monkeys SARS-CoV-2 S2 sensitivity Seroconversion seroconversion time Simoa tested Ultrasensitive digital detection. vaccination virus wild-type [DOI] 10.1016/j.bios.2022.114710 PMC 바로가기
SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong KongArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] age Anti-RBD IgG antibody children consequence COVID-19 diagnosed group Health healthcare Hong Kong IgG incidence individual Infection lowest measure nucleoprotein Older omicron ORF8 Public Receptor binding Receptor binding domain reflect SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection seropositive Serosurveillance subclinical infection vaccination variant [DOI] 10.1080/22221751.2022.2106899 PMC 바로가기
The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockade장기간의 백신 유발 항SARS-CoV-2 면역 반응은 TNFα 차단으로 인해 양과 질이 저하됩니다.Article Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 백일해, 변종, 진단, 파상풍, [키워드] Activation acute respiratory syndrome alteration analysed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-TNF-α appear Autoimmune Autoimmune diseases blockade bystander Cell changes in chronic inflammatory disease Cohort comparable Control coronavirus COVID-19 Decline drugs Effect Efficacy ELISA flow cytometry groups healthy humoral immune response IgG immune cell populations immune response immunoblot investigated less Live virus Necrosis Neutralization assay neutralize neutralizing antibody neutralizing capacity Older omicron Patient patients plasma Plasma cell recipient reduced response SARS-CoV-2 second vaccination significantly T cell subset titre TNF-α TNFα tumor necrosis factor inhibitors tumor necrosis factor-α vaccination Vaccine variants of concern virus VoC was increased while [DOI] 10.1002/jmv.28063 PMC 바로가기
SARS-CoV-2 antibody profile of naturally infected and vaccinated individuals detected using qualitative, semi-quantitative and multiplex immunoassaysArticle Published on 2022-12-012022-11-15 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] anti-N antibody anti-RBD anti-S2 Anti-spike antibodies antibody Antibody profile Antigen average Cohort demonstrated exhibited HCW healthcare worker IgG immune immunoassay individual Infection infection cohort mRNA vaccines multiplex natural infection Patient positive produced reactivity SARS-CoV-2 SARS-CoV-2 antibody semi-quantitative Support target vaccinated individual vaccination [DOI] 10.1016/j.diagmicrobio.2022.115803 PMC 바로가기
Humoral response and safety of the third booster dose of BNT162b2 mRNA COVID-19 vaccine in patients with multiple sclerosis treated with ocrelizumab or fingolimodArticle Published on 2022-12-012022-11-15 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 진단, [키워드] binding antibody unit BNT162b2 mRNA BNT162b2 mRNA vaccine booster dose collected Control COVID-19 COVID-19 vaccine dose expressed fingolimod HCs humoral Humoral response IgG IgG antibody IgG level Laboratory mRNA mRNA vaccine Multiple multiple sclerosis Ocrelizumab of BNT162b2 Patient positive predict quantified reported SARS-CoV-2 sclerosis serum sample severe adverse event socio-demographic threshold Tolerability treated Trimeric spike protein Vaccine vaccine dose variable [DOI] 10.1007/s00415-022-11296-4 PMC 바로가기
An Engineered IgG-VHH Bispecific Antibody against SARS-CoV-2 and Its VariantsArticle Published on 2022-12-012023-07-10 Journal: Small methods [Category] COVID19(2023년), [키워드] bispecific antibody IgG novel format. SARS-CoV-2 VHH [DOI] 10.1002/smtd.202200932 PMC 바로가기
Safety and immunogenicity of inactivated COVID-19 vaccination in adult rheumatic patients in South China: a prospective studyArticle Published on 2022-11-302022-11-15 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome antibodies antibody Blood C-reactive protein carried Cell China CLIA Coronavirus-2 COVID-19 COVID-19 vaccination COVID-19 vaccine decrease described detect distribution dose effective Effectiveness healthy control high-risk population ICV IgG immunization immunoassay immunogenicity immunosuppressive agent inactivated Inactivated vaccine Infection inoculated Logistic regression analysis magnitude methotrexate parameter Patient patients patients treated positive response Prednisolone Prospective Study Protective antibody receiving recruited response to vaccination rheumatic disease Safe Safety SARS-CoV-2 serious adverse reaction South [DOI] 10.1080/21645515.2022.2090176 PMC 바로가기
Decay rate of antiS1/S2 IgG serum levels after 6 months of BNT162b2 vaccination in a cohort of COVID-19-naive and COVID-19-experienced subjectsArticle Published on 2022-11-302023-07-09 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), [키워드] antibody COVID-19 Decline IgG Kinetics SARS-CoV-2 spike Vaccine [DOI] 10.1080/21645515.2022.2060018 PMC 바로가기