Reprofiling of approved drugs against SARS-CoV-2 main protease: an in-silico study
Article
Published on
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발,
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발,
[키워드] acarbose
approach
approved
approved drug
Azithromycin
binding
catalytic site
clinical trial
COVID-19
COVID-19 pandemic
docking
drug
Drug discovery
drug target
functional
help
high-affinity binding
Hyaluronic acid
identify
in-silico
inhibitors of SARS-CoV-2
Interaction
Lopinavir
M pro
Molecular dynamics simulation
MPro
nonstructural proteins
nsp5
performed
polyprotein
protease
residue
reveal
SARS-CoV-2
Screening
survival
these compound
viral replication
virus
[DOI] 10.1080/07391102.2020.1845976 PMC 바로가기 [Article Type] Article
[DOI] 10.1080/07391102.2020.1845976 PMC 바로가기 [Article Type] Article