Characteristics of SARS-CoV-2 Transmission among Meat Processing Workers in Nebraska, USA, and Effectiveness of Risk Mitigation MeasuresSynopsis Published on 2021-04-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome adverse outcome aligned attack rate confirmed case coronavirus coronavirus disease COVID-19 COVID-19 incidence demographics determine diagnosed disease transmission Effect Effectiveness group high risk impacted incidence Infection Infection prevention Intervention Masks measure meat processing industries men Mitigation occupational exposures outcome pandemic physical barrier physical barriers policy interventions processing Racial reduce SARS-CoV-2 severe acute respiratory syndrome Coronavirus statistically significant reduction The United States USA viruses worker [DOI] 10.3201/eid2704.204800 PMC 바로가기 [Article Type] Synopsis
Epidemiological surveillance of SARS-CoV-2 by genome quantification in wastewater applied to a city in the northeast of France: Comparison of ultrafiltration- and protein precipitation-based methods프랑스 북동부 도시에 적용된 폐수 게놈 정량을 통한 SARS-CoV-2의 역학 감시: 한외여과 및 단백질 침전 기반 방법의 비교Article Published on 2021-04-012022-09-11 Journal: International journal of hygiene and environmental [Category] SARS, 치료기술, [키워드] addition alcohol applied approach circulation clinical setting clinical settings collected Community Concentration Concentration methods COVID-19 COVID-19 case COVID-19 outbreak decrease develop Diagnosis eight epidemiological epidemiological surveillance evaluate evaluated France Genome human population inhibitors lockdown MONITOR Patient phage predict Prevalence processing Protein purification quantification required Respiratory samples RNA RNA extract RNA extracts RT-PCR SARS-CoV-2 SARS-CoV-2 genome Surveillance the SARS-CoV-2 genome Ultrafiltration undetectable university viral genome viral genomes Virological wastewater were used [DOI] 10.1016/j.ijheh.2021.113692 PMC 바로가기 [Article Type] Article
Assessing critical gaps in COVID-19 testing capacity: the case of delayed results in EcuadorCOVID-19 테스트 용량의 심각한 격차 평가: 에콰도르에서 지연된 결과의 경우Research Article Published on 2021-04-012022-09-01 Journal: BMC Public Health [Category] MERS, SARS, 진단, [키워드] Assessing association average clinical care clinically collected contribute country COVID-19 COVID-19 cases COVID-19 testing Critical database death rate death rates Decision making Decision-making diagnostic diagnostic testing Diseases Ecuador Generalized linear model Health policy highest highlight individual inequality Infectious diseases information information management Laboratory limitation management Ministry of Health mitigate National physical processed processing reported resource Result RT-PCR testing Sample subsequent supplementary material Testing Vaccination strategies Vaccination strategy WHO’ [DOI] 10.1186/s12889-021-10715-x PMC 바로가기 [Article Type] Research Article
Drugmonizome and Drugmonizome-ML: integration and abstraction of small molecule attributes for drug enrichment analysis and machine learningDrugmonizome 및 Drugmonizome-ML: 약물 농축 분석 및 기계 학습을 위한 소분자 속성의 통합 및 추상화Original Article Published on 2021-03-312022-09-11 Journal: Database: The Journal of Biological Databases and [Category] SARS, 신약개발, 치료제, [키워드] addition approved assist attribute biological processe can be used Consensus Critical database databases drug enrichment analysis Gene Expression heterogeneous in vitro independent indication indications induce information knowledge machine learning molecular overlap Peripheral Neuropathy predict processing resource SARS-CoV-2 Side effect Side effects similarity small molecule Small molecules targets understanding utility Viral viral replication [DOI] 10.1093/database/baab017 PMC 바로가기 [Article Type] Original Article
Sonographic Diagnosis of COVID-19: A Review of Image Processing for Lung UltrasoundBig Data Published on 2021-03-092022-10-31 Journal: Frontiers in Big Data [Category] COVID-19, [키워드] affected assist automated can be used Care Characteristics classification Computed tomography COVID-19 COVID-19 diagnosis COVID-19 infection detect determine diagnose Diagnosis early diagnosis early phase Evidence Health hospital Image Image processing increase in Interpretation lung lung involvement Lung ultrasound machine learning manifestation MONITOR outbreak pandemic Patient performed processing professional Protective researcher review Segmentation subsequent sustained the disease Ultrasound X-ray [DOI] 10.3389/fdata.2021.612561 PMC 바로가기 [Article Type] Big Data
[Methods of SARS-CoV-2 detection in tissue][조직 내 SARS-CoV-2 검출 방법]Review Published on 2021-03-012022-09-11 Journal: Der Pathologe [Category] SARS, 치료기술, [키워드] alteration Antigen antigens approach Autopsies autopsy studies biopsies Chain Reaction choice COVID-19 COVID-19 patient curated database death detection diagnostic dominant electron electron microscopy English error evaluated feature fixation Fluorescence Fluorescence in situ hybridization histopathological finding immunofluorescence immunohistochemistry IMPROVE In situ hybridization information Interpretation interval less material Microscopy Morphological oder pathophysiology phase polymerase chain polymerase chain reaction preanalytical phase processing Protein reverse transcriptase Reverse transcriptase polymerase chain reaction RNA RT-PCR sample collection SARS-CoV-2 detection SARS-CoV‑2 sensitivity Sensitivity and specificity significantly higher source of error specificity surgical specimen surgical specimens the disease tissue tissues validation study [DOI] 10.1007/s00292-021-00919-8 PMC 바로가기 [Article Type] Review
Subtle Influence of ACE2 Glycan Processing on SARS-CoV-2 RecognitionResearch Article Published on 2021-02-192022-10-29 Journal: Journal of Molecular Biology [Category] COVID-19, MERS, SARS, [키워드] Abstract ACE2 ACE2 variants analyzed angiotensin-converting enzyme 2 binding cellular receptor glycan glycan engineering glycans glycoprotein glycosylated glycosylation human cells Impact influence Interaction LC-MS Modification modifications molecular basis N-linked glycan processing receptor Recognition SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral sensitivity severity sialic acid significantly Spike protein SPR suggested surface plasmon resonance variant viral spike virus was determined [DOI] 10.1016/j.jmb.2020.166762 PMC 바로가기 [Article Type] Research Article
In silico analysis suggests less effective MHC-II presentation of SARS-CoV-2 RBM peptides: Implication for neutralizing antibody responsesIn silico 분석은 SARS-CoV-2 RBM 펩타이드의 덜 효과적인 MHC-II 제시를 시사합니다: 항체 반응 중화에 대한 의미Research Article Published on 2021-02-112022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] Analysis Antibody Response Antibody responses B cell cross-reactivity develop effective epitope Epitopes evaluated Examining General population Infection lack less MHC-II MHC-II alleles microbial neutralizing antibody Neutralizing antibody response peptide peptides Post-infection predicted processing raising RBM receptor binding motif SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody Spike protein subject Support T cell T cell epitope T cell memory the spike protein [DOI] 10.1371/journal.pone.0246731 PMC 바로가기 [Article Type] Research Article
Rapid processing of SARS-CoV-2 containing specimens for direct RT-PCR직접 RT-PCR을 위한 SARS-CoV-2 함유 검체의 신속한 처리Research Article Published on 2021-02-102022-09-10 Journal: PLoS ONE [Category] MERS, 진단, 치료기술, [키워드] aliquot Asymptomatic automated collected COVID-19 detect detectable detection diagnostic diagnostic test diagnostic testing Effective mass glycol include increase Infection inhibitor inhibitors initial Mass screening pandemic performed pre-symptomatic processed processing provide purification Rapid reaction reduce RNA purification robust room temperature RT-PCR RT-qPCR Saliva saliva specimen saliva specimens SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus sensitivity specimen specimens Swab swab specimen swab specimens temperature the SARS-CoV-2 virus Transmission transport medium Treatment Universal Transport Medium Viral Viral RNA viral RNA detection virus viruses [DOI] 10.1371/journal.pone.0246867 PMC 바로가기 [Article Type] Research Article
Airborne aerosol olfactory deposition contributes to anosmia in COVID-19공기 중 에어로졸 후각 침착은 COVID-19의 후각 상실증에 기여합니다Research Article Published on 2021-02-052022-09-10 Journal: PLoS ONE [Category] MERS, 치료제, [키워드] aerosol Aerosols Affect airway Anosmia Atypical average blinded bypassing Concentration contribute COVID-19 COVID-19 patients determine droplet dysfunction explain Fluorescein greater Inflammation Inhaled majority mechanism nebulized olfactory olfactory dysfunction Olfactory epithelium opacification Particulate processing provide quantification randomization respiratory respiratory epithelium Result significantly significantly higher subjects subsequent transmission of SARS-CoV-2 upper airway Volunteer [DOI] 10.1371/journal.pone.0244127 PMC 바로가기 [Article Type] Research Article