The calcium-dependent protein kinase 1 from Toxoplasma gondii as target for structure-based drug designToxoplasma gondii의 칼슘 의존성 단백질 키나제 1을 구조 기반 약물 설계의 대상으로 삼다Article Published on 2018-02-012024-08-12 Journal: Parasitology [Category] 말라리아, [키워드] Calcium-dependent protein kinase CDPK1 drug design protein structure Toxoplasma gondii [DOI] 10.1017/S0031182017001901 PMC 바로가기
Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae폐렴구균에서의 능력 필루스 주요 필린 ComGC의 구조Article Published on 2017-08-252024-08-01 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] Horizontal gene transfer major pilin Microbiology nuclear magnetic resonance (NMR) pneumococci protein structure Streptococcus pneumoniae transformation type IV pili [DOI] 10.1074/jbc.M117.787671 PMC 바로가기
Identification of Capsid/Coat Related Protein Folds and Their Utility for Virus ClassificationOriginal Research Published on 2017-03-102023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] capsid fold superfamily protein structure SCOP virion virus taxonomy [DOI] 10.3389/fmicb.2017.00380 PMC 바로가기 [Article Type] Original Research
Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230Article Published on 2016-09-162024-08-27 Journal: Brain stimulation [Category] 말라리아, [키워드] malaria Pfs230 Pichia pastoris protein structure recombinant protein expression transmission blocking Vaccine yeast
NMR reveals structural rearrangements associated to substrate insertion in nucleotide‐adding enzymesNMR은 뉴클레오타이드 추가 효소에서 기질 삽입과 관련된 구조적 재배치를 드러냅니다.journal-article Published on 2016-04-012024-08-01 Journal: Protein Science [Category] 폐렴구균 감염증, [키워드] DUF925 nucleotide-binding protein PF06042 Protein dynamics protein structure solution NMR. [DOI] 10.1002/pro.2872 [Article Type] journal-article
In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discoveryarticle Published on 2014-08-312024-09-01 Journal: Chemical Biology & Drug Design [Category] 말라리아, [키워드] Chemical structure Drug discovery functional genomics (gene KO/KI) kinase malaria phosphatase protein structure [Article Type] article
Atlas of coronavirus replicase structureArticle Published on 2013-12-162022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Atla bioinformatics coronavirus Coverage Cryoelectron microscopy functional in viral International Microscopy NMR NMR spectroscopy nonstructural protein Pathogenesis produced Protein protein structure Proteins Replication SARS Coronavirus SARS-CoV Small angle X-ray scattering Structure structures variety X-ray crystallography X-ray scattering [DOI] 10.1016/j.virusres.2013.12.004 PMC 바로가기 [Article Type] Article
Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native “ball-and-socket” interacting residues by an affinity tagarticle Published on 2013-10-312024-09-01 Journal: Protein Science [Category] 말라리아, [키워드] artifact dimer interface hyperoxidation malaria peroxidase protein structure radiation damage structural genomics [Article Type] article
Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutininArticle Published on 2013-03-192023-05-31 Journal: Philosophical Transactions of the Royal Society B: [Category] 신종인플루엔자, 조류인플루엔자, [키워드] fixed-effects likelihood protein evolution protein structure random-effects likelihood relative solvent accessibility sialic acid [DOI] 10.1098/rstb.2012.0334 PMC 바로가기
Structural and functional analysis of the hemagglutinin-esterase of infectious salmon anaemia virusArticle Published on 2010-04-142022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] activities Ala Amino acid amino acid substitution Analysis Atlantic salmon bovine Bovine coronavirus catalytic site Combination determinant different disease domain enzymatic activity enzyme expression feature functional had no Hemagglutinin-esterase Hemagglutinin-esterase (HE) infectious Infectious salmon anaemia virus (ISAV) Influenza introduced molecular orthomyxovirus Protein protein structure Proteins purification Quantitative Receptor binding Receptor-destroying enzyme (RDE) Recombinant secretory HE (recHE) red blood cells representing resolved responsible selected Ser Serine Structural analysis Surface glycoprotein variants virulence virulent virus [DOI] 10.1016/j.virusres.2010.03.020 PMC 바로가기 [Article Type] Article