Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 20212021년 3월 독일, 5개의 SARS-CoV-2 RAT(Rapid Antigen Tests)에서 우려되는 B.1.1.7 및 B.1.351의 새로운 SARS-CoV-2 변이체 감지Rapid Communication Published on 2021-04-222022-09-10 Journal: Eurosurveillance [Category] MERS, SARS, 변종, 치료기술, [키워드] Abbott analysed B.1.1.7 B.1.351 cell culture supernatant clinical sample comparable conditions detect detection dilutions DMEM FIVE Germany investigated Laboratory molecular nal von minden new SARS-CoV-2 performance rapid antigen test Rapid antigen test(s) Rapid antigen tests RapiGEN RAT RATs Roche Saliva SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Siemens Surveillance Variant(s) of Concern variants of concern VoC while [DOI] 10.2807/1560-7917.ES.2021.26.16.2100413 PMC 바로가기 [Article Type] Rapid Communication
Evaluation of a laboratory-based high-throughput SARS-CoV-2 antigen assay for non-COVID-19 patient screening at hospital admission입원 시 non-COVID-19 환자 스크리닝을 위한 실험실 기반 고처리량 SARS-CoV-2 항원 분석 평가Rapid Communication Published on 2021-04-152022-09-12 Journal: Medical Microbiology and Immunology [Category] MERS, 진단, [키워드] Analysis analytical sensitivity Antigen antigen tests Applying arbitrary unit characterized concerning COVID-19 criteria cut-off described DiaSorin disadvantage evaluated Evaluation Hospital admission LIAISON lowering Non-COVID-19 non-COVID-19 patient Non-COVID-19 patients Patient PCR PCR-based assay PCR-based assays rapid antigen test Rapid antigen tests RAT RATs reagents RT-qPCR SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigen test Screening sensitivity specificity Test the WHO [DOI] 10.1007/s00430-021-00706-5 PMC 바로가기 [Article Type] Rapid Communication
Evaluation of rapid SARS-CoV-2 antigen tests, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 patientsCOVID-19 환자의 일련의 비인두 표본을 사용한 신속한 SARS-CoV-2 항원 검사, AFIAS COVID-19 Ag 및 ichroma COVID-19 Ag의 평가Clinical Trial Published on 2021-04-082022-08-15 Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] ( RdRP Accuracy AFIAS COVID-19 Ag analyzed Antigen antigen kinetics collected conjunction COVID-19 COVID-19 patient cycle threshold diagnostic Diagnostic accuracy diagnostic sensitivity Early detection evaluated false negativity ichroma TM COVID-19 Ag investigated kappa value kappa values molecular molecular test Molecular tests nasopharyngeal nasopharyngeal specimen negative control negative controls point-of-care post-symptom onset profile PSO rapid antigen test Rapid antigen tests RAT RATs RdRP SARS-CoV-2 SARS-CoV-2 antigen sensitivity specificity specimen test results TM COVID-19 Ag Viral Viral load were assessed were used [DOI] 10.1371/journal.pone.0249972 PMC 바로가기 [Article Type] Clinical Trial
SARS-CoV-2 Diagnostic Tests: Algorithm and Field Evaluation From the Near Patient Testing to the Automated Diagnostic PlatformMedicine Published on 2021-04-062022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Admission Algorithm Antigen antigen detection assays Asymptomatic asymptomatic patient automated conditions conducted COVID-19 COVID-19 diagnosis diagnostic diagnostic tests Europe evaluated field First wave immunoassay Inpatients intrinsic Laboratory limit of detection Median viral load molecular molecular test NAAT not significantly different Outpatient Patient PCR PCR cycle PCRs point-of-care point-of-care tests Population Practitioner Rapid antigen tests Rapid test resource reverse transcription PCR SARS-CoV-2 sensitivity seriously ill patients symptomatic symptomatic patient Testing threshold was performed [DOI] 10.3389/fmed.2021.650581 PMC 바로가기 [Article Type] Medicine
Performance Characteristics of BinaxNOW COVID-19 Antigen Card for Screening Asymptomatic Individuals in a University Setting대학 환경에서 무증상 개인을 선별하기 위한 BinaxNOW COVID-19 항원 카드의 성능 특성Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 치료기술, [키워드] Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analytical sensitivity Analytical specificity Antigen Asymptomatic Asymptomatic individuals asymptomatic screening BinaxNOW COVID-19 antigen card Card caution coronavirus COVID-19 cycle threshold false-negative false-negative results individual Infection median performance positive presenting Rapid antigen tests reverse transcription-PCR RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 RNA Screening setting severe acute respiratory syndrome Coronavirus significantly lower specimen study participant Study participants TaqPath Thermo Fisher university Utah Viral load [DOI] 10.1128/JCM.03282-20 PMC 바로가기 [Article Type] Article
COVID-19 Rapid Antigen Test as Screening Strategy at Points of Entry: Experience in Lazio Region, Central Italy, August–October 2020입국 지점 스크리닝 전략으로서의 COVID-19 신속 항원 테스트: 이탈리아 중부 라치오 지역에서의 경험, 2020년 8월–10월Article Published on 2021-03-132022-09-01 Journal: Biomolecules [Category] SARS, 변종, 진단, [키워드] addition Algorithm approach candidate confirmation contribute COVID-19 COVID-19 pandemic experience feasible Fluorescence followed by gold gold standard Health identify Infectious virus Information System Italy Lazio Mass screening mass surveillance molecular molecular test Molecular tests Point point of entry point-of-care Probability proportion public health Rapid rapid antigen test Rapid antigen tests Region Regional reported RT-PCR SARS-CoV-2 SARS-CoV-2 variants Screening semi-quantitative sensitivity Spread Strategy Support surveillance testing System Test Travel Viral viral spread virus [DOI] 10.3390/biom11030425 PMC 바로가기 [Article Type] Article
Double-blind, randomized, controlled, trial to assess the efficacy of allogenic mesenchymal stromal cells in patients with acute respiratory distress syndrome due to COVID-19 (COVID-AT): A structured summary of a study protocol for a randomised controlled trialCOVID-19(COVID-AT)로 인한 급성 호흡 곤란 증후군 환자에서 동종 간엽 기질 세포의 효능을 평가하기 위한 이중 맹검, 무작위, 대조 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-062022-09-10 Journal: Trials [Category] MERS, 바이오마커, 임상, 치료제, [키워드] 1:1 24 hours 7-point ordinal scale acute respiratory distress acute respiratory distress syndrome Administered administration Admission Adult patient Adult patients Adverse Adverse drug reactions AEs age All trial participants all-cause mortality allergy Allogeneic ARDS assessment assigned baseline Biomarker blinded Blinding C-reactive protein carcinoma carcinoma in situ carried cellular chain change childbearing potential Chloroquine Clinical practice clinical status clinical trial coagulation test coagulation tests conducted Control control arm Course COVID COVID-19 CRF criteria CT scan cumulative incidence current Cytokines D-dimer Day death described determined by Diagnosis disease dissemination double-blind drug Duration ECMO Efficacy Efficacy and safety element eligible End endpoints enrolment EudraCT evaluate evaluate the effect event exclusion criteria Extracorporeal extracorporeal membrane oxygenation failure ferritin fibrosis FiO2 form GRADE grade 3 greater Haemodialysis handling hemofiltration history hospital Hospitalization hydroxy ICU ICU admission IMPROVE include inclusion criteria Informed consent intravenous Intravenous administration intravenous dose intubation Invasive mechanical ventilation invasive ventilation investigational medicinal product involved laboratory confirmation laboratory-confirmed SARS-CoV-2 infection lactation LDH less Level Local Lopinavir Lopinavir/ritonavir lung disorder lymphocyte marker Mechanical mechanical ventilation Medicine Medicines Mesenchymal stromal cells moderate to severe Mortality MSC negative pregnancy test neoplasm neutrophil neutrophil counts Non-invasive number objective occur off-label opinion Ordinal Scale organ oropharyngeal swab oropharyngeal swabs Other outcome oxygen oxygen saturation Oxygen therapy PaO2 PaO2/FiO2 ratio parameters participant Patient PCR percentage Placebo polymerase chain reaction Pregnancy primary endpoint product Production profile progression protocol Pulmonary embolism pulmonary fibrosis Pulmonary function tests randomised randomised controlled trial randomization Randomized Randomly Rapid antigen tests reaction receive recruitment Registered Remdesivir report respiratory Respiratory distress syndrome Resuscitation Ritonavir SAEs Sample size SARS-COV-2 infection secondary Secondary endpoints Sequential Organ Failure Assessment Serious Adverse Events SOFA Spain specificity specimen Sponsor Standard of care status stromal cell stromal cells Study protocol subpopulations supplemental oxygen supplementary material syndrome the cell the disease the patient the primary endpoint the WHO time Tocilizumab Tolerability Treatment treatment arm treatment for COVID-19 treatment group Treatment protocol Trial trial participant Trial registration unit website women worldwide pandemic written consent [DOI] 10.1186/s13063-020-04964-1 PMC 바로가기 [Article Type] Letter
Limits and Opportunities of SARS-CoV-2 Antigen Rapid Tests: An Experienced-Based PerspectiveCommunication Published on 2021-01-052022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Abbott addition analyzed Antigen benefit bronchoalveolar clinical setting correlation COVID-19 diagnostic eight evaluated gold standard Lateral flow test material opportunity PanBio PCR ranged Rapid Rapid antigen tests RapiGEN rising Roche SARS-CoV-2 SARS-COV-2 infection sensitivity specificity tested the SARS-CoV-2 [DOI] 10.3390/pathogens10010038 PMC 바로가기 [Article Type] Communication
Comparison of Rapid Antigen Tests for COVID-19COVID-19에 대한 신속한 항원 검사의 비교Comparative Study Published on 2020-12-102022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 can not clinics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient detect diagnose Diagnosis examined Infectious virus isolate isolates Isolation lateral flow immunoassay Lateral flow immunoassays Local PCR positive quantitative PCR Rapid rapid antigen test Rapid antigen tests RAT RATs respiratory reverse transcription RT-qPCR SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus specimen Test tested Viral Viral antigen viral antigens virus [DOI] 10.3390/v12121420 PMC 바로가기 [Article Type] Comparative Study