DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in miceArticle Published on 2021-02-042022-10-04 Journal: Scientific Reports [Category] MERS, 유전자 메커니즘, [키워드] addition anti-SARS-CoV-2 immune response binding characterized coding coronavirus disease COVID-19 DNA vaccine DNA vaccines ectodomain global pandemic Health Heterologous immunization immunogenic imperative induce mice neutralize neutralizing antibody outbreak platform prefusion conformation Prevent Pseudotyped virus rapid response response RNA SARS-CoV-2 SARS-CoV-2 spike glycoprotein SARS-CoV-2 vaccine specific IgG antibody Spike protein Spread T cell responses the SARS-CoV-2 virus trimer Vaccine vaccine candidate [DOI] 10.1038/s41598-021-82498-5 PMC 바로가기 [Article Type] Article
Outbreak of Severe Vomiting in Dogs Associated with a Canine Enteric Coronavirus, United KingdomResearch Published on 2021-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] affected canine canine enteric coronavirus coronavirus diet disease dog dogs Effect Effectiveness Electronic health record enteric enteric infections Evidence gastroenteritis gastrointestinal disease Health lack outbreak Outbreaks Population rapid response reported significant increase significantly Statistical modeling Surveillance Syndromic surveillance United Kingdom vaccination viruses vomiting [DOI] 10.3201/eid2702.202452 PMC 바로가기 [Article Type] Research
Humoral immune responses and neutralizing antibodies against SARS-CoV-2; implications in pathogenesis and protective immunitySARS-CoV-2에 대한 체액 면역 반응 및 중화 항체; 병인 및 보호 면역에 미치는 영향Review Published on 2021-01-292022-09-12 Journal: Biochemical and Biophysical Research Communication [Category] SARS, 진단, [키워드] ACE2 Administered antibodies antibody approach B cells block viral entry cellular receptor characterized Clinical outcome Clinical use COVID-19 pathogenesis defined determine disease severity domain epitope glycoprotein Humoral response IgA IgM antibody immune response Immunity implication infected individual infected individuals information interact mAbs magnitude management monoclonal antibody natural infection neutralizing antibody occur other coronaviruses pandemic Pathogenesis PROTECT Protective protective immunity rapid response RBD Receptor binding domain Reinfection reported response SARS-CoV-2 Seroconversion the antibody the Spike therapy utility Vaccine Vaccines Viral protein virus Virus-specific IgG with COVID-19 [DOI] 10.1016/j.bbrc.2020.10.108 PMC 바로가기 [Article Type] Review
In the interest of public safety: rapid response to the COVID-19 epidemic in Vietnam공공 안전을 위해: 베트남의 COVID-19 전염병에 대한 신속한 대응Review Published on 2021-01-012022-09-11 Journal: BMJ Global Health [Category] 치료기술, [키워드] addition adoption border control case studies Community conditions controlling coordination country COVID-19 COVID-19 case COVID-19 epidemic death diagnose Early detection effective effective communication Epidemic epidemic waves Epidemiology evidence of Factor finding Health Health promotion highlight hospital hospitals implementation information Laboratory lockdown measure Measures National outbreak patients plan potential transmission public health rapid response reported required response resulting risk Risk assessment SARS SARS-CoV-2 Spread status treat widespread [DOI] 10.1136/bmjgh-2020-004100 PMC 바로가기 [Article Type] Review
Addressing Operational Challenges Faced by COVID-19 Public Health Rapid Response Teams in Non–United States SettingsConcepts in Disaster Medicine Published on 2020-12-222022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, MERS, [키워드] applicability approach center challenge Control Coordinate coronavirus disease country COVID-19 COVID-19 outbreak Critical disease outbreaks effective emergency preparedness emergency responders emergency response Health health-care implementation information Laboratory Measures mechanism MONITOR prevention Public public health Rapid rapid response rapid response teams Responder responders response RRT setting state Support team United State [DOI] 10.1017/dmp.2020.487 PMC 바로가기 [Article Type] Concepts in Disaster Medicine
Epidemic Spread and Its Management Through Governance and Leadership Response Influencing the Arising Challenges Around COVID-19 in Pakistan—A Lesson Learnt for Low Income Countries With Limited ResourcePublic Health Published on 2020-12-102022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 169 days survey adopted affected Asian challenge China combating confirmed cases continuous monitoring coronavirus coronavirus disease country COVID-19 COVID-19 case COVID-19 outbreak current status death deaths Defense effective Europe expected Governance governance quick response Government Health help income leadership lesson Limited media mitigate National outcomes pandemic preventive measure preventive measures rapid response remained reported resource response responses Russia Spread USA Wuhan [DOI] 10.3389/fpubh.2020.573431 PMC 바로가기 [Article Type] Public Health
Vital signs assessed in initial clinical encounters predict COVID-19 mortality in an NYC hospital system초기 임상 만남에서 평가된 활력 징후는 NYC 병원 시스템에서 COVID-19 사망률을 예측합니다Observational Study Published on 2020-12-092022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, [키워드] analysed Analysis BMI Care Characteristics Chronic kidney disease city clinical evaluation conducted COVID-19 COVID-19 mortality COVID-19 related mortality disease Diseases effective Epidemic Factor Factors Health Health care heart rate hospital identify Immediate initial Kidney disease laboratory-confirmed Logistic regression lower oxygen saturation machine learning Male sex measure Medical research Mortality network Older age outbreak outcome outcomes oxygen predict predicted predictor public health rapid response respiratory rate Retrospective study risk factor Risk factors SARS-CoV-2 training set vital sign with COVID-19 [DOI] 10.1038/s41598-020-78392-1 PMC 바로가기 [Article Type] Observational Study
COVID-19, an Opportunity for Developing Countries?Public Health Published on 2020-11-232022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] approach catastrophic cause Community consequence coronavirus Coronavirus infections country COVID-19 COVID-19 outbreak death develop Developing disease global pandemic hygiene incidence Infection low-and lower-middle-income countries majority mandatory measure not affect opportunity pandemic Perspective rapid response reduce reservoirs resource South America Spread WHO World Health Organization [DOI] 10.3389/fpubh.2020.548708 PMC 바로가기 [Article Type] Public Health
Rapid assessment of psychological and epidemiological correlates of COVID-19 concern, financial strain, and health-related behavior change in a large online sampleResearch Article Published on 2020-11-112022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Adults age Anxiety Canada Complication confirmed cases country COVID-19 depressive symptom early phase elevated epidemiological epidemiological data Europe global pandemic greater impacted implication indicated Infection Intervention Older pandemic participant Psychological Rapid rapid response recruited risk self-quarantine significantly spread of COVID-19 The United States widespread with COVID-19 [DOI] 10.1371/journal.pone.0241990 PMC 바로가기 [Article Type] Research Article
Rapid Response Subunit Vaccine Design in the Absence of Structural Information구조적 정보가 없는 상황에서 신속한 반응 서브유닛 백신 설계Immunology Published on 2020-11-042022-09-11 Journal: Frontiers in Immunology [Category] 비임상, [키워드] Antigen Arenaviridae breath CEPI Clamp clinical trial Coalition Coalition for Epidemic Preparedness Innovations conducted coronavirus disease Coronavirus disease 2019 Course COVID-19 Disease X expected expressed expression level funding homogeneity Innovation lesson membrane fusion membrane fusion protein molecular clamp pandemic Paramyxoviridae Pathogens Phase I platform pre-fusion pre-fusion conformation Protein Rapid rapid response response screened subunit Subunit vaccine trimeric Vaccine development variant Viral viral pathogens virus [DOI] 10.3389/fimmu.2020.592370 PMC 바로가기 [Article Type] Immunology