Epidemiology and Genetic Analysis of SARS-CoV-2 in Myanmar during the Community Outbreaks in 20202020 년 지역 사회 발발 동안 미얀마의 SARS-Cov-2의 역학 및 유전자 분석Article Published on 2022-01-272022-09-10 Journal: Viruses [Category] SARS, 변종, [키워드] Analysis B.6 Case fatality rate caused changed clade Community community transmission confirmed case constant COVID-19 death effective epidemic wave epidemic waves epidemiological situation Fatality rate First wave Genetic GISAID Lineage mitigate Molecular epidemiology Pangolin lineage public health measure public health measures reached Registered reproductive reproductive number SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 strain second wave situation South Asian spread to state strain Strains the epidemic Travel whole-genome whole-genome sequences whole-genome sequencing [DOI] 10.3390/v14020259 PMC 바로가기 [Article Type] Article
COVID-19 reinfections among naturally infected and vaccinated individuals자연적으로 감염되고 예방 접종을받은 개인의 COVID-19 재감염Article Published on 2022-01-262022-09-10 Journal: Scientific Reports [Category] SARS, 변종, 치료기술, 치료법, [키워드] 1080 95% CI added age antibody baseline Chain Reaction clinical feature Cohort COVID-19 COVID-19 testing Critical disease diabetes Diabetes Mellitus died elicited Epidemiology Follow-up Genome sequences hospitalised patient Hospitalised patients Hospitalized hospitalized patients hypertension individual individuals less male naïve natural infection Naturally oxygen oxygen support participant polymerase chain reaction Population positive positive patient Post-infection proportion real-time reverse transcriptase-polymerase chain reaction Registered Reinfection required responsible reverse transcriptase risk risk of infection risk ratio rRT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants sequence severe disease significantly higher tested vaccinated individual vaccinated individuals vaccination variants viral infection whole-genome sequencing [DOI] 10.1038/s41598-022-05325-5 PMC 바로가기 [Article Type] Article
Phylogenetic analysis of SARS-CoV-2 viruses circulating in the South American region: Genetic relations and vaccine strain matchArticle Published on 2022-01-212022-10-04 Journal: Virus research [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] acute respiratory syndrome Amino acid Analysis anti-SARS-CoV-2 antibody antibody B.1 Beta caused circulating codon usage coronavirus coronavirus disease COVID-19 Delta effective Efficacy escaped Evolution Evolution of SARS-CoV-2 family Coronaviridae Gamma Genotype genotypes immune resistance increase in Lambda MOST nucleocapsid pandemic Phylogenetic polymerase Protein recent reduce reduced responsible RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 virus Significant South South America spike gene Substitution the spike protein Transmissibility Transmission Vaccine vaccine strain variant variants of interest virus virus variant VOCs VOIs was performed Wuhan-Hu-1 [DOI] 10.1016/j.virusres.2022.198688 PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 in the state of Delaware reveals tremendous genomic diversity델라웨어 주에서 SARS-COV-2의 게놈 감시는 엄청난 게놈 다양성을 보여줍니다.Research Article Published on 2022-01-192022-09-10 Journal: PLoS ONE [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha analyzed average B.1.1.7 B.1.351 B.1.429 B.1.617.2 Beta clade coding collected coronavirus Critical Delta Epsilon Gamma Genome genomic Genomic surveillance International international airports lineages location Mutation offer pangolin Perspective respiratory reveal SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains sequence sequenced Sequencing severe acute respiratory syndrome Coronavirus Spread strain Surveillance These data Transmission unique were used [DOI] 10.1371/journal.pone.0262573 PMC 바로가기 [Article Type] Research Article
Two years of SARS-CoV-2 infection (2019–2021): structural biology, vaccination, and current global situationReview Published on 2022-01-142022-10-31 Journal: The Egyptian Journal of Internal Medicine [Category] COVID-19, [키워드] Administered Cancer confirmed case country COVID-19 COVID-19 case COVID-19 infection death diabetes disease drug drugs Epidemiology Genetic variation globe highlighting Host immunization increase in Infection information Injury Interaction kidney liver Neurological disorders New parental pathway recent reported risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 virus Spread structural biology the SARS-CoV-2 Trial vaccination Vaccine vaccine dose [DOI] 10.1186/s43162-021-00092-7 PMC 바로가기 [Article Type] Review
The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variantsSARS-CoV-2 베타에 대한 항체 반응은 다른 변이체와의 항원 거리를 강조합니다Article Published on 2022-01-122022-09-10 Journal: Cell Host & Microbe [Category] MERS, SARS, 변종, 진단, [키워드] Abstract Alter Analysis antibody Antibody Response antigenic antigenic structure Beta Beta variant binding conserved COVID-19 Delta E484K epitope escape Express immune responses include individual infected with SARS-CoV-2 K417N mAb mAbs multiple mutation multiple mutations mutated Mutation N-terminal domain N501Y neutralization neutralize Neutralizing Neutralizing antibodies neutralizing antibody NTD other variant pandemic Patient performed RBD Receptor-binding domain Recognition recognize residue residues SARS-CoV-1 SARS-CoV-1 and -2 SARS-CoV-2 SARS-CoV-2 strain separated sequence serum Spike protein Structure structure-function the receptor-binding domain the SARS-CoV-2 the spike protein Vaccine Vaccine-induced immunity variant variants of SARS-CoV-2 viruses [DOI] 10.1016/j.chom.2021.11.013 PMC 바로가기 [Article Type] Article
Variant analysis of SARS-CoV-2 strains with phylogenetic analysis and the Coronavirus Antiviral and Resistance Database계통발생학적 분석과 코로나바이러스 항바이러스 및 내성 데이터베이스를 사용한 SARS-CoV-2 균주의 변이체 분석Research Article Published on 2022-01-112022-09-10 Journal: Journal of Comparative Effectiveness Research [Category] COVID19(2023년), MERS, SARS, 변종, 치료제, [키워드] (alpha Alpha analyses Analysis appear B.1.1.7 B.1.351 B.1.525 B.1.526 B.1.617 bioinformatics coronavirus COVID-19 COVID-19 case Illumina material Missense mutation Missense mutations Next-generation sequencing Phylogenetic phylogenetic analyses Phylogenetic analysis processed reported resistance SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 strain SARS-CoV-2 variants SARS-CoV-2 variation SARS-CoV-2 variations Stanford University strain Strains Surveillance Turkey variant Variation were used [DOI] 10.2217/cer-2021-0208 PMC 바로가기 [Article Type] Research Article
HiSpike Method for High-Throughput Cost Effective Sequencing of the SARS-CoV-2 Spike GeneMedicine Published on 2022-01-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Antigen Beta Cell Community cost effective country COVID-19 COVID-19 patient Delta effective escape mutants fraction genomic global effort health systems help High-throughput HiSpike host receptor Immunity Intensive Laboratory morbidity and mortality neutralizing antibody NGS omicron Omicron variant pandemic pathogenicity provide Real-time monitoring reduce regions resource risk SARS-CoV-2 SARS-CoV-2 sequencing SARS-CoV-2 spike protein SARS-CoV-2 strain sequence sequenced Sequencing spike spike gene Spike protein spike variant spike variants Spread Surveillance susceptible the SARS-CoV-2 Transmissibility Vaccine vaccine immunity variant variants variants of concern widespread [DOI] 10.3389/fmed.2021.798130 PMC 바로가기 [Article Type] Medicine
Identification and characterisation of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case치명적인 COVID-19 사례에서 생산적인 동시 감염에서 SARS-CoV-2 및 인간 알파헤르페스바이러스 1의 식별 및 특성화Research Article Published on 2022-01-102022-09-10 Journal: Memórias do Instituto Oswaldo Cruz [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplicon-based sequencing Analysis approach can not causal relationship Chain Reaction characterisation Coinfection collected Coronaviridae coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity determine Diagnosis etiological agent explain fatal COVID-19 Genetic variant herpes simplex virus Herpes Simplex Virus 1 Herpesviridae high viral load HSV-1 Human identification Infection metagenomic Nasopharyngeal swab nasopharyngeal swab sample Neurological symptom Neurological symptoms neutralisation test outcome Patient PCR performed plaque Plaque assay plaque phenotypes polymerase chain polymerase chain reaction predominant reduction respiratory responsible reverse transcription reverse transcription real-time polymerase chain reaction RT-qPCR SARS-CoV-2 SARS-CoV-2 strain Sequencing severe symptom severe symptoms severity strain Strains suggested Support the disease Viral Viral load Virological virus [DOI] 10.1590/0074-02760210176 PMC 바로가기 [Article Type] Research Article
Prediction of the effects of the top 10 nonsynonymous variants from 30229 SARS-CoV-2 strains on their proteins30229 SARS-CoV-2 균주의 상위 10개 동의어가 아닌 변이체가 단백질에 미치는 영향 예측Article Published on 2022-01-062022-09-11 Journal: F1000Research [Category] SARS, 변종, [키워드] addition affecting Amino acid amino acid residue Analysis analyzed bioinformatics cause co-mutation computational studies Computational study consequence COVID-19 D614G Deleterious Effect Frequency functions highest Impact in vitro in vivo Multiple studies Mutation N protein N501Y nine nonsynonymous mutation nonsynonymous mutation. Nonsynonymous mutations nonsynonymous variant Nsp12 nsp5 ORF1 ORF1a ORF1b ORF3 ORF3a outbreak P323L pathogen prediction Protein protein structure Proteins Q57H reported S protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequences SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 strain SARS-CoV-2 virus stability Structure the SARS-CoV-2 genome wild type Wuhan Wuhan, China [DOI] 10.12688/f1000research.72904.2 PMC 바로가기 [Article Type] Article