Cynomolgus Macaque as an Animal Model for Severe Acute Respiratory Syndrome
Research Article
[키워드] 2003
acute respiratory syndrome
Adequate
affected
animal
animal model
cause
caused
changed
Chest radiograph
children
clinical disease
Clinical laboratory test
clinically
clone
coronavirus
cynomolgus macaque
demonstrated
develop
disease
effective vaccine
Evidence
finding
group
Health
Infected
Infection
infectious
intravenous
intravenously
Jason
macaque
majority
Mild
Model
moderate
mucosal route
nare
Neutralizing antibodies
NHP
NHPs
parameter
Pathogenesis
peaked
Pneumonia
Postinfection
produced
required
respiratory
SARS-CoV
SARS-CoV infection
SARS-CoV Urbani
severe
significantly
similarity
symptomatic
syndrome
viral replication
virus
were infected
wild-type
[DOI] 10.1371/journal.pmed.0030149 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pmed.0030149 PMC 바로가기 [Article Type] Research Article