Beneficial Treatment Outcomes of Severe COVID-19 Patients Treated Entirely in Primary Care Settings With Dexamethasone Including Regimen—Case Series ReportPharmacology Published on 2021-08-122022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome Affect approach Care case sery caused condition coronavirus coronavirus disease Corticosteroids COVID-19 COVID-19 patient Dexamethasone disease Health health center Including majority management nonpharmacological treatment organ systems outcome pandemic pharmacological positive primary care Primary Health Care provided report rising SARS-CoV-2 Sery setting severe COVID-19 patient Severe patient statistical supported treated Treatment [DOI] 10.3389/fphar.2021.684537 PMC 바로가기 [Article Type] Pharmacology
Clinical features and death risk factors in COVID-19 patients with cancer: a retrospective studyResearch Article Published on 2021-08-052022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] addition Analysis Bladder cancer Breast cancer C-reactive protein C-reactive protein (CRP Cancer category clinical clinical feature Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CRP death diabetes difference disease Dyspnea enrolled Factor feature identify incidence laboratory result lung cancer median age Mortality much higher Neutrophil-to-lymphocyte ratio NLR nomogram non-severe group non-severe patients outcome performed predict Probability proportion PSM Result Retrospective study risk factor Risk factors severe group Severe patient severity significantly Smokers Spread supplementary material two group [DOI] 10.1186/s12879-021-06495-9 PMC 바로가기 [Article Type] Research Article
Day‐by‐day blood pressure variability in hospitalized patients with COVID‐19Original Article Published on 2021-07-312022-10-29 Journal: Journal of clinical hypertension (Greenwich, Conn. [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval admitted to ICU antihypertensive medication association blood pressure blood pressure variability branch Clinical outcome clinical outcomes confounding factors COVID‐19 COVID‐19 Critical Critically ill patient critically ill patients diastolic Diastolic blood pressure died discharged discharged patient discharged patients greater hospital Hospitalization Hospitalized hospitalized patient independent Inpatient investigated Mortality Odds ratio participant Patient Retrospective analysis Severe patient significantly study participant Tongji Hospital transferred Treatment Variability Variation VIM Wuhan, China [DOI] 10.1111/jch.14338 PMC 바로가기 [Article Type] Original Article
Innate and Adaptive Immune Assessment at Admission to Predict Clinical Outcome in COVID-19 PatientsArticle Published on 2021-07-292022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] activated adaptive Adaptive immunity Admission age antibody panel assessment Biomarker C-reactive protein carried CD27 CD28 CD38 CD8 cellular circulating clinical component COVID-19 COVID-19 disease COVID-19 pandemic D-dimer evaluate evaluated ferritin flow cytometry Frequency HLADR humoral IL-6 immune parameter immune response immune system immunological profile Innate Innate immunity Innate lymphoid cells interleukin-6 Logistic regression analysis lymphopenia Mild Mild symptom NK cells non-classical monocyte Non-classical monocytes Older Oxygen therapy Patient phenotype predicted Predictive Predictive model Prognosis prognostic biomarker Regulatory Regulatory T cell SARS-CoV-2 SARS-COV-2 infection severe disease Severe patient severity significantly increased Th1 the disease the patient [DOI] 10.3390/biomedicines9080917 PMC 바로가기 [Article Type] Article
Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Severity in COVID-19 PatientsMicrobiology Published on 2021-07-192022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 16S rRNA gene 95% CI Analysis association Bacteria C-reactive protein changes in clinical clinical parameter Clinical severity conducted coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity cross-sectional demonstrated Diversity Dysbiosis functions Gut gut microbiota gut microbiota composition Hospitalized hospitalized patient Host immune Inflammatory intensive care investigated Isolation microbial microbiota mild COVID-19 patients moderate multicenter multivariable logistic regression Multivariable regression analysis prognostic biomarker risk factor scale Sequencing severe COVID-19 Severe patient severity Shannon—Weiner diversity index the WHO was performed WHO Clinical Progression Scale [DOI] 10.3389/fmicb.2021.705020 PMC 바로가기 [Article Type] Microbiology
High Performance of SARS-Cov-2N Protein Antigen Chemiluminescence Immunoassay as Frontline Testing for Acute Phase COVID-19 Diagnosis: A Retrospective Cohort StudyMedicine Published on 2021-07-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute infections Analysis analyzed Antigen can be used characteristic chemiluminescence immunoassay collected Control COVID-19 COVID-19 patient COVID-19 patients diagnostic diagnostic performances early infection identify immunoassay IMPROVE Infection mild patients N protein Non-COVID-19 patients pathogen patients patients with COVID-19 performance phase recovered patient SARS-CoV-2N protein antigen sensitivity serum serum samples Severe patient specific antibody specificity Spread suggested Surveillance Testing testing strategies were used [DOI] 10.3389/fmed.2021.676560 PMC 바로가기 [Article Type] Medicine
Umifenovir in hospitalized moderate to severe COVID-19 patients: A randomized clinical trialReview Published on 2021-07-102022-10-04 Journal: International immunopharmacology [Category] 임상, 치료제, [키워드] ABG, Atrial blood gas Analysis Arbidol assigned Chest CT scans Clinical improvement clinical trial Committee conducted Control control group control groups COVID-19 COVID-2019, Coronavirus Disease 2019 Cox regression model dose effective Effectiveness Efficacy Ethics evaluate GCS, Glasgow Coma Scale hazard Hospitalized hospitalized patient HR, hazard ratio ICU, Intensive care unit Infection injection Intervention intervention group ITT population legally authorized representatives LFT, liver function test median Medical Sciences moderate moderate-severe Mortality non-ICU patient Open-label participant Patient positive positive RT-PCR Prognosis Randomized randomized clinical trial Randomly Ratio receive Registered Result SARS-CoV-2 SARS-CoV-2, severe acute respiratory syndrome coronavirus2 severe COVID-19 Severe patient single-center statistically significant statistically significant difference Subcutaneous time treat treated Treatment treatment group Trial TTCI TTCI, Time to clinical improvement two group umifenovir university VBG, Venous blood gas [DOI] 10.1016/j.intimp.2021.107969 PMC 바로가기 [Article Type] Review
Clinical features and predictors for patients with severe SARS-CoV-2 pneumonia at the start of the pandemic: a retrospective multicenter cohort studyResearch Article Published on 2021-07-082022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] 95%CI Analysis carried China Chinese clinical clinical feature Clinical outcome clinical recovery collected Corticosteroids demographic dose feature Final Hospital stay identify independent risk factor indicated Laboratory likelihood Logistic regression Lymphocyte count lymphocyte counts Mild moderate moderate disease multicenter cohort study multivariate non-severe cases Odds ratio pandemic Patient Peripheral blood Pneumonia predictor Prospective Study reduced Registered registry Result retrospective risk factor Risk factors SARS-CoV-2 SARS-CoV-2 pneumonia Severe case severe cases Severe patient severe patients severe SARS-CoV-2 significantly small sample size Symptoms systematic corticosteroid viral shedding was performed [DOI] 10.1186/s12879-021-06335-w PMC 바로가기 [Article Type] Research Article
Associação da Hipertensão com a Gravidade e a Mortalidade de Pacientes Hospitalizados com COVID-19 em Wuhan, China: Estudo Unicêntrico e RetrospectivoArtigo Original Published on 2021-07-072022-10-28 Journal: Arquivos Brasileiros de Cardiologia [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission adopted Aggressive analyzed association Betacoronavírus Betacoronavirus, Severe Acute Respiratoty Syndrome caused city Comorbidades Comorbidities coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19/complicações COVID-19/complications creatinine Critical diagnosed diagnosed with COVID-19 diagnosis of COVID-19 died discharge discharged enrolled Fatores de Risco Hipertensão hospital hospitalized patient hypertension hypertensive patient Inflammation kidney Kidney injury liver Lung function lymphopenia median age men Mortality mortality rate objective pacientes hospitalizado Patient patients Result retrospective Risk factors Síndrome Respiratória Aguda Grave SARS-CoV-2 Severe case Severe patient severity significance level significantly higher single-center Spread statistical analysis TNT Treatment with COVID-19 Wuhan Wuhan, China [DOI] 10.36660/abc.20200733 PMC 바로가기 [Article Type] Artigo Original
Duration of Supplemental Oxygen Requirement and Predictors in Severe COVID-19 Patients in Ethiopia: A Survival AnalysisObservational Study Published on 2021-07-012022-10-04 Journal: Ethiopian Journal of Health Sciences [Category] SARS, 임상, [키워드] 95%CI Affect age assist can be used Care center Complication conducted COVID-19 COVID-19 patient death determinant distribution Duration Ethiopia Factor group groups hazard ratio hospital identify Interpretation log-rank management median Older oxygen Oxygen requirement P-value Patient predictor predictors Prevent prospective observational study Requirement resource Result rising risk Severe patient Shortness of breath supplemental oxygen Supplemental oxygen therapy survival survival analysis the disease was used were used [DOI] 10.4314/ejhs.v31i4.3 PMC 바로가기 [Article Type] Observational Study