A Closed-Loop Approach to Fight Coronavirus: Early Detection and Subsequent TreatmentArticle Published on 2022-10-202022-11-15 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] biosensing caused Complication coronavirus COVID-19 COVID-19 pandemic Critical detection Diagnosis early diagnosis effective electrical Epidemic epidemic control Health helping include Infection invasive manuscript MONITOR neurostimulation patients photoacoustic imaging reducing respiration monitor. SARS-CoV-2 Severe patient Ventilation ventilator [DOI] 10.3390/bios12100900 PMC 바로가기
Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patientsArticle Published on 2022-10-182022-11-15 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome antibody profiling blood sample cell death circulating neutrophil contributing to Control coronavirus COVID-19 degranulation disease disease severity driver dysregulated elevated experiment functions G-MDSC gene expression signature Granulocytic healthy donor hospitalized COVID-19 hospitalized COVID-19 patient Humoral response identify IgA IgA antibody IgG antibody Immunoglobulin induce longitudinal Mortality NETosis neutrophil Neutrophils Patient phagocytosis phenotype plasma plasma proteomics response RNA sequencing SARS-CoV-2 severe coronavirus disease severe COVID-19 severe disease Severe patient severity Subtypes survived transcriptomics [DOI] 10.1016/j.xcrm.2022.100779 PMC 바로가기
A systematic review and meta-analysis of the IgA seroprevalence in COVID-19 patients: Is there a role for IgA in COVID-19 diagnosis or severity?COVID-19 환자의 IgA 혈청 유병률에 대한 체계적인 검토 및 메타 분석: COVID-19 진단 또는 중증도에서 IgA의 역할이 있습니까?Meta-Analysis Published on 2022-10-012022-09-11 Journal: Microbiological research [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody association asymptomatic patients Biomarker caused coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 disease determine diagnostic diagnostic test diagnostic tests disease Efficacy Health health problems Humoral response humoral responses IgA Immunity in some include Infection manuscript Meta-analysis Mild observé Patient problems produced Research respiratory SARS-CoV-2 SARS-CoV-2 PCR Seroprevalence severe acute respiratory syndrome Coronavirus Severe patient severe patients severity susceptibility symptomatic systematic review Vaccines [DOI] 10.1016/j.micres.2022.127105 PMC 바로가기 [Article Type] Meta-Analysis
Preliminary investigation of gene expression levels of PAPP-A, STC-2, and HIF-1α in SARS-Cov-2 infected patientsArticle Published on 2022-09-012022-11-16 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] alteration Analysis Clinical data condition COVID-19 COVID-19 infection COVID-19 patients cytokine Cytokine storm demonstrated determine evaluated expression extracted RNA Gene Expression gene expression level gene expression pattern healthy individual HIF-1α individuals induce infected patient Infection influence Laboratory material molecular mRNA expression Other pandemic PAPP-A Patient patients with COVID-19 Peripheral blood positive correlation pro-inflammatory molecules Prognosis Real-time PCR SARS-CoV-2 Severe patient STC-2. stimulate target was used [DOI] 10.1007/s11033-022-07710-9 PMC 바로가기
Immune modulation as a consequence of SARS-CoV-2 infectionArticle Published on 2022-08-302022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] adaptive Alter alteration B cells CD3 CD8 Clinical severity clinically COVID-19 COVID-19 pathogenesis Cytokine storm D-dimer levels Decreased detrimental effects diagnosed elevated Elevation enrolled Frame healthy controls IFN-γ IgA level IgG IL-10 IL-6 IL-8 ILCs immune immune response Immunity Mild moderate modulated modulation negative correlation NK cell NK cells Patient Plasma cell pro-inflammatory cytokine Protective reduced reduction SARS-CoV-2 SARS-COV-2 infection Serum level severe COVID-19 disease Severe patient severe patients significantly subset T cell T cells the disease TNF-α [DOI] 10.3389/fimmu.2022.954391 PMC 바로가기
Are lipid ratios and triglyceride-glucose index associated with critical care outcomes in COVID-19 patients?지질 비율과 트리글리세리드-글루코스 지수는 COVID-19 환자의 중환자 치료 결과와 관련이 있습니까?Article Published on 2022-08-012022-09-11 Journal: PLoS ONE [Category] 바이오마커, [키워드] adjusted age Analysis biochemical marker biochemical markers BMI carried cholesterol coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 mortality COVID-19 patient Critical care demonstrated evaluate Glucose HDL-C high-density insulin insulin resistance LDL-C Lipid lipoprotein Logistic regression analysis low-density Low-density lipoprotein Mortality multivariate multivariate logistic regression analysis outcome performed predictor Prognosis Regression regression models Research severe coronavirus disease Severe patient severe patients severity Sex significantly higher significantly lower statistically survivor Total cholesterol Triglyceride with COVID-19 [DOI] 10.1371/journal.pone.0272000 PMC 바로가기 [Article Type] Article
Coagulation parameters abnormalities and their relation to clinical outcomes in hospitalized and severe COVID-19 patients: prospective study Research Published on 2022-08-012022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] abnormality activated biochemical biochemical parameter clinical Clinical outcome Coagulation coagulation parameter Coagulation parameters Concentration COVID-19 COVID-19 patient COVID-19 severity cut-off D dimer D-dimer death diagnosed difference Dyspnea enrolled fibrinogen hematological Hospitalized inflammatory markers LDH non-severe group Older outcome parameter parameters Partial Patient patients Predictive Prospective Study prothrombin risk Sensitivity and specificity severe COVID-19 severe group Severe patient severity severity of COVID-19 survival the patient time were recorded [DOI] 10.1038/s41598-022-16915-8 [Article Type] Research
Anti-cardiolipin IgG autoantibodies associate with circulating extracellular DNA in severe COVID-19항 카디오리핀 IgG 자가항체는 심각한 COVID-19에서 순환하는 세포외 DNA와 연관됩니다Article Published on 2022-07-222022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, 치료법, [키워드] analyzed Anticoagulant association autoantibody circulating citrullinated histone citrullinated histones collected COVID-19 COVID-19 severity disease severity exacerbate extracellular DNA glycoprotein IgA IgG IgG and IgM IgM investigated Lupus lupus anticoagulant marker mild patients NET neutrophil Neutrophil extracellular trap Neutrophil extracellular traps Patient patients with COVID-19 positive patient positive patients Prevalence prothrombin SARS-CoV-2 sera severe COVID-19 severe disease Severe patient severe patients severity the disease with COVID-19 [DOI] 10.1038/s41598-022-15969-y PMC 바로가기 [Article Type] Article
Outcome of COVID-19 in interstitial lung disease patients treated with anti-inflammatory drugs and antiviral drugs항염증제 및 항바이러스제 치료를 받는 간질성 폐질환 환자의 코로나19 결과Article Published on 2022-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] 치료제, [키워드] Affect age and sex anti-inflammatory drug antiviral drug antiviral drugs Antiviral treatment coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid therapy Corticosteroids COVID-19 COVID-19 patient COVID-19 patients death Diagnosis evaluate Favipiravir fibrosis honeycomb lung HRCT Idiopathic pulmonary fibrosis ILD immunosuppressive agent Immunosuppressive agents increased risk Interstitial lung disease interstitial pneumonia lung Lung disease medical record medical records mortality rate no statistical difference outcome Patient patients treated patients with COVID-19 proportion pulmonary fibrosis Remdesivir reported risk factor Risk factors selected severe disease Severe patient severe patients treated Univariate analysis [DOI] 10.1016/j.jiac.2022.04.006 PMC 바로가기 [Article Type] Article
Association between thrombocytopenia and the severity of Covid-19 infection among hospitalized Egyptian patientsResearch article Published on 2022-07-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 바이오마커, [키워드] acute respiratory syndrome addition ARDS association cause caused Clinical sign COVID-19 Critically ill Critically ill patient critically ill patients cross-sectional death Disseminated intravascular coagulopathy distress evaluate group hemorrhage Hospitalized hospitalized patients hypoxia Infection Laboratory lung dysfunction occurred outcome parameter Patient patients with COVID-19 Pneumonia radiological evidence Respiratory failure risk Severe acute respiratory syndrome Severe patient severity severity of COVID-19 statistically statistically significant difference symptomatic patient syndrome systemic illness thrombocytopenia virus was done [DOI] 10.1016/j.amsu.2022.103973 [Article Type] Research article