Stimulation – Page 8 – Communicable Diseases Research

Interference between rhinovirus and influenza A virus: a clinical data analysis and experimental infection study

라이노바이러스와 인플루엔자 A 바이러스의 간섭: 임상 데이터 분석 및 실험적 감염 연구

Article

Published on 2020-10-092022-09-10
Journal: The Lancet. Microbe [Category] MERS, 신종인플루엔자, 치료기술,

Guidelines for TMS/tES clinical services and research through the COVID-19 pandemic

COVID-19 전염병을 통한 TMS/tES 임상 서비스 및 연구에 대한 지침

Article

Published on 2020-07-012022-09-11
Journal: Brain stimulation [Category] SARS, 비임상,

[키워드] Addiction adverse events Alternating Current Analysis anticipated Brain breath catalyst Clinical research clinical research - clinics Comorbidities consensus paper consequence COVID-19 COVID-19 pandemic current demographics described develop Direct Direct Current document Effect effort electrical Electrical Stimulation equipment facilitate focus framework guideline human resource Human resources indications intensity International Intervention Laboratory life-threatening maintain many case many cases mental health mind mitigate neurological Non-invasive Non-invasive brain stimulation Numerous Outbreaks outlined pandemic pediatric Perspective Population positive protocols provide reflect Regulatory Research resource resources risk robust scientific rigor social distancing Stage Sterilization Stimulation stroke Telemedicine Transcranial alternating current stimulation Transcranial direct current stimulation Transcranial electrical stimulation Transcranial magnetic stimulation Treatment urgency
[DOI] 10.1016/j.brs.2020.05.010 PMC 바로가기 [Article Type] Article

Dorsal Root Ganglion Stimulation for Thoracic Neuralgia: A Report of Six Cases

article

Published on 2019-05-072024-09-02
Journal: Cureus [Category] 대상포진,

[키워드] dorsal root ganglion neuropathic pain Pain Stimulation Thoracic thoracic neuralgia Thorax
[DOI] 10.7759/cureus.4615 PMC 바로가기 [Article Type] article

Reduced monocyte and macrophage TNFSF15 /TL1A expression is associated with susceptibility to inflammatory bowel disease

감소된 단핵구 및 대식세포 TNFSF15 /TL1A 발현은 염증성 장 질환에 대한 감수성과 관련이 있습니다

Research Article

Published on 2018-09-102022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] Activation addition Affect allele animal model animal models association assumption bowel breakdown cell type cell types characterized chronic chronic inflammation compromise condition contribute Crohn’s disease cytokine decreased expression determine disease disease risk ENCODE ENhance Ethnic groups Evidence expression expression measurement functional genetic change genetic loci Genetic variant Genome-wide association studies Genotype Gut Haplotype healthy volunteer Hypothesis IBD IBD loci Immune homeostasis immunopathology increase Inflammation Inflammatory bowel disease intestinal list locus lymphocyte Macrophage macrophage differentiation macrophages mechanism monocyte Monocytes murine model murine models over patients Peripheral blood peripheral blood monocytes persist polymorphism Polymorphisms predisposition pro-inflammatory promote protective role protein level protein levels question receptor regulated regulatory region required responsible risk risk allele RNA shown Signaling Stimulation subtype susceptibility T cell T cells TNF TNFSF15 ulcerative colitis upstream variant variety
[DOI] 10.1371/journal.pgen.1007458 PMC 바로가기 [Article Type] Research Article

Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cells

B 세포 발달 동안 비활성 X에서 Xist RNA의 손실은 활성화된 B 세포에서 동적 YY1 종속 2단계 과정으로 복원됩니다.

Research Article

Published on 2017-10-092022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation

Mycobacterium leprae 항원 자극 후 유전자 발현의 유전자 제어 해독

Research Article

Published on 2017-08-092022-09-06
Journal: PLoS Genetics [Category] Communicable Disease, 한센병,

[키워드] activated Affect Antigen bacterium binding site Blood cells caused conducted criteria Differential gene expression disease disease control displaying enrichment eQTL Evidence exposure to expression FDR Gene Expression gene expression level Genetic genetic control Genetic variation Genetic variations genomic highlight Host host genetics host response host responses human host human infectious disease immune Immune cell immune cells Infection Infectious disease Interaction involved knowledge leprosy loci mechanism modulate modulation Mycobacterium leprae natural selection nucleotide outlined pathogen Pathogenesis pathogenicity Patient performed Positive selection proportion Quantitative reaction Regulatory reported Seven significantly Single nucleotide polymorphism single nucleotide polymorphisms SNPs Stimulation suggested susceptibility the disease transcript transcription factor transcription factors transcriptional response triggered upregulation variant variants Variation while whole blood cell whole blood cells
[DOI] 10.1371/journal.pgen.1006952 PMC 바로가기 [Article Type] Research Article

Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1

단백질 키나제 Cak1의 발현 감소를 통한 칸디다 알비칸스 필라멘트/생물막 조절기 우회

Research Article

Published on 2016-12-092022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] absence activating Activation antimicrobial Antimicrobials bacterial pathogen biofilm bypass Candida Candida albican Candida albicans Cell cell cycle cell growth cell proliferation contribute coupling dependence determinant diminished Effectiveness Express expresse expression Filamentous functional Gene Expression Genes growth implicated induce Infection infections information inhibition invasive kinase leads Medical devices Mutation occur organism pathogen Pathogens proliferation property Protein protein kinase reduced regulator Regulatory required Screen Stimulation strain Strains Target genes the cell transcription factor transcription factors wild-type
[DOI] 10.1371/journal.pgen.1006487 PMC 바로가기 [Article Type] Research Article

Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway

죽상경화증 퇴행 동안 플라크 대식세포의 전사체에 대한 후성유전체 분석은 Wnt 신호 전달 경로의 활성화를 보여줍니다

Research Article

Published on 2014-12-042022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] activated Affect Analysis annotations approach arterial plaque macrophage arteries Atherosclerosis binding site canonical Cell cell motility cell type chromatin circulating condition control group demonstrated detect differentially expressed drug treatments eight element enrichment epigenomic eQTL Evidence expression foam cell functional Gene Expression humans identify in vitro in vivo increase Inflammation inflammatory disease inflammatory state innate immune system less Lipoproteins lowering Macrophage Macrophage response macrophage responses macrophages mice Migration molecular mouse model network overlap plaque plaque macrophage plaque macrophage response plaque macrophage responses plaque macrophages plaque regression plaques plasma lipoprotein plasma lipoproteins power promoter promoters reducing regressing plaque regressing plaques Regression Regression model regression models regulatory region response reversed risk significantly SNPs statins statistically Stimulation Systems biology TCF/LEF therapeutic target transcription factor transcription factors transcriptional change Transcriptome upregulated upregulated gene upregulated genes upstream validation study while Wnt Wnt signaling Wnt signaling pathway β-catenin
[DOI] 10.1371/journal.pgen.1004828 PMC 바로가기 [Article Type] Research Article

Gene Set Signature of Reversal Reaction Type I in Leprosy Patients

나병 환자의 역전 반응 유형 I의 유전자 세트 서명

Research Article

Published on 2013-07-112022-09-06
Journal: PLoS Genetics [Category] Communicable Disease, 한센병,

[키워드] a major accurate Affect affected Analysis Anti-inflammation anti-inflammatory mediator anti-inflammatory mediators Antigen antigens arachidonic acid Author Blood conducted Critical cured defined Definition diagnosed Diagnosis different differential expression differentially regulated genes Endemic enrolled environmental factor environmental factors evaluated Factor functional Gene genes encoding Genetic genetic background genetic profile Genome healthy individual healthy individuals immune incidence increased risk Inflammatory response Innate immunity leprosy majority mediators metabolism Mycobacterium leprae nerve damage Pathogenesis Patient performed Predictive pro-inflammatory Prospective Study reaction reflect Regulation replicated retrospective Retrospective study reversal reversal reactions RNA sample RNA samples signature Stimulation subsequent subset Transcriptome Trigger triggers Type validation Validity Whole blood
[DOI] 10.1371/journal.pgen.1003624 PMC 바로가기 [Article Type] Research Article

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다

Research Article

Published on 2013-04-042022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer
[DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article