Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopeniaSARS-CoV-2 백신 접종과 관련된 면역 혈전성 혈소판 감소증에서 항체 매개 응고촉진 혈소판Article Published on 2021-08-012022-09-12 Journal: Haematologica [Category] MERS, SARS, 진단, [키워드] administration Admission aggregation analyzed antibody assays Autopsy capillary ChAdOx1 nCoV-19 COVID-19 pandemic COVID-19 vaccination enzyme female flow cytometry glomerular healthy healthy volunteer immune immunological male median median age morbidity and mortality organ outcome P-selectin Pathogenesis Patient performed PF4 Phosphatidylserine Platelet platelet activation Prevent procoagulant procoagulant marker SARS-CoV-2 vaccine Severe infection significant increase thrombotic thrombotic complication treated vaccination Vaccine venous volunteers [DOI] 10.3324/haematol.2021.279000 PMC 바로가기 [Article Type] Article
What have we learned about COVID-19 volunteering in the UK? A rapid review of the literatureResearch Article Published on 2021-07-282022-10-28 Journal: BMC Public Health [Category] Coronavirus, SARS, [키워드] activities activity applied benefit Community Community champion Community engagement conducted COVID-19 database dimension effort eligible emotional Factor finding group groups initial screening knowledge Local Mutual aid National pandemic peer-reviewed rapid review Research Result Self-isolation social network Support systematic review volunteering volunteers women [DOI] 10.1186/s12889-021-11390-8 PMC 바로가기 [Article Type] Research Article
Determinants of having severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in Egypt이집트에서 중증급성호흡기증후군 코로나바이러스 2 중화항체 보유 여부 결정요인Original Article Published on 2021-07-152022-09-10 Journal: Influenza and Other Respiratory Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome antibodies antibody assist Asymptomatic asymptomatic and mild cases chest pain Community community settings conducted confidence interval coronavirus covariates COVID‐19 COVID‐19 determinant determinants diarrhea disease dry cough Dyspnea Egypt estimate Fever headache Immunity in some Infection laboratory confirmation Local loss of taste loss of taste or smell malaise mild case mild cases Neutralizing antibodies neutralizing antibody Odds ratio Odds ratios Older participant predictor Prevention and control Result SARS‐CoV‐2 Seroconversion seropositive Seroprevalence Surveillance Symptom Taste volunteers [DOI] 10.1111/irv.12889 PMC 바로가기 [Article Type] Original Article
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States미국에서 COVID-19 대유행의 첫 6개월 동안 진단되지 않은 SARS-CoV-2 혈청양성Report Published on 2021-07-072022-09-12 Journal: Science Translational Medicine [Category] MERS, SARS, 진단, [키워드] 95% CI adjust African American age analyzed antibody Asymptomatic Behavioral risk factor Blood blood sample Characteristics collected common cold COVID-19 COVID-19 pandemic death defined diagnosed diagnostics drop ELISA estimate Ethnicity evaluate Factor female First wave FIVE highest Hispanic IgG and IgM IgM antibodies implementation in some individual Infection infections information Lung function MOST National oxygen oxygen saturation pandemic participant patients Prevalence prevalence rate processed proportion provided question Receptor binding domain reflected SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike protein selected Selection bias Seropositivity Sex Spike protein Spike protein receptor binding domain study participant Study participants survey System the spike protein the United State The United States These data United States volunteers were used with COVID-19 [DOI] 10.1126/scitranslmed.abh3826 PMC 바로가기 [Article Type] Report
Individual- and group-level network-building interventions to address social isolation and loneliness: A scoping review with implications for COVID19Research Article Published on 2021-06-252022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] abstracts activating build Characteristics component conducted connection contributed COVID19 creating diagnostics Effectiveness element facilitator finding group identify impacted implication include individual information Intervention Isolation loneliness performed retrieved risk social distancing social isolation structures volunteers Web of Science [DOI] 10.1371/journal.pone.0253734 PMC 바로가기 [Article Type] Research Article
To Volunteer or Not? Perspectives towards Pre-Registered Nursing Students Volunteering Frontline during COVID-19 Pandemic to Ease Healthcare Workforce: A Qualitative StudyArticle Published on 2021-06-212022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] Care caused conducted COVID-19 COVID-19 pandemic explain Factor finding health workforce healthcare healthcare service Healthcare system healthcare worker identity IMPROVE interview management motivational factor Nursing nursing students Pandemics positive professional identity Providing Qualitative qualitative study recruited strained student suggested Support thematic analysis thought transcribed Volunteer volunteering volunteers was used [DOI] 10.3390/ijerph18126668 PMC 바로가기 [Article Type] Article
BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants Research Published on 2021-06-102022-10-05 Journal: Nature [Category] SARS, 변종, 임상, [키워드] acute respiratory syndrome B.1.525 B.1.617 B.1.617.1 B.1.617.2 BNT162b2 vaccine coronavirus coronavirus disease Coverage COVID-19 elicited genetic background geometric mean immunization India lineages neutralization neutralize neutralized Nigeria pandemic pathogenicity plaque reduction neutralization SARS-CoV-2 SARS-CoV-2 variant second dose sera serum sample spike glycoprotein strain Support susceptibility tested therapeutic titre Transmissibility USA-WA1/2020 Vaccine variant virus virus strain volunteers [DOI] 10.1038/s41586-021-03693-y [Article Type] Research
Autoantibodies to heat shock protein 60, 70, and 90 are not altered in the anti-SARS-CoV-2 IgG-seropositive humans without or with mild symptoms열 충격 단백질 60, 70 및 90에 대한 자가항체는 항SARS-CoV-2 IgG 혈청 양성인 사람에서 경증의 증상이 있거나 없는 변경되지 않습니다.Short Communication Published on 2021-06-022022-09-12 Journal: Cell stress & chaperones [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 anti-SARS-CoV-2 antibody autoantibodies autoantibody Autoimmunity cellular organelles chaperone circulating conserved COVID-19 cytoplasm dose elicit enzyme-linked immunosorbent evaluate evaluated Extracellular healthy healthy volunteer Heat shock heat shock protein Heat shock proteins, Hsps Human humoral immune response Hypothesis IgA IgG IgM Immunity immunogenic include member Mild symptom molecular mRNA vaccine naïve participant Proteases Protein released remained SARS-CoV-2 Serum level Severe acute respiratory syndrome corona virus 2, SARS-CoV-2 stress conditions viral spike protein virus Volunteer volunteers [DOI] 10.1007/s12192-021-01215-3 PMC 바로가기 [Article Type] Short Communication
Resuscitative Effect of Centhaquine (Lyfaquin ®) in Hypovolemic Shock Patients: A Randomized, Multicentric, Controlled Trial저혈량성 쇼크 환자에서 Centhaquine(Lyfaquin®)의 소생 효과: 무작위, 다중심, 대조 시험Clinical Trial Published on 2021-06-012022-09-11 Journal: Advances in therapy [Category] SARS, 비임상, 임상, [키워드] 1:1 added adverse event all-cause mortality animal model animal models ARDS base deficit baseline Blood both groups breath Centhaquine Clinical outcome comparable conducted control group Controlled demographics determine diastolic distress Effect effective Efficacy female patient greater Haemoglobin Haemorrhage healthy Hypovolemia hypovolemic Hypovolemic Shock ICU IMPROVE improvement Improvements in both group in both groups increase in Lactate less major surgery male MODS multicentre multiple organ dysfunction multiple organ dysfunction syndrome normal saline observation period organ dysfunction syndrome Patient Randomized respiratory distress Respiratory distress syndrome Resuscitation Resuscitative agent Scoring Shock Standard of care Support syndrome System the patient Tolerability Vasopressor vasopressors ventilator volunteers was recorded [DOI] 10.1007/s12325-021-01760-4 PMC 바로가기 [Article Type] Clinical Trial
A novel LC-MS/MS method for determination of the potential antiviral candidate favipiravir for the emergency treatment of SARS-CoV-2 virus in human plasma: Application to a bioequivalence study in Egyptian human volunteers인간 혈장에서 SARS-CoV-2 바이러스의 긴급 치료를 위한 잠재적인 항바이러스 후보 favipiravir의 결정을 위한 새로운 LC-MS/MS 방법: 이집트 인간 지원자의 생물학적 동등성 연구에 적용Article Published on 2021-05-302022-09-11 Journal: Journal of pharmaceutical and biomedical analysis [Category] SARS, 치료제, [키워드] acetic acetic acid adopted Antiviral antiviral agent application applied bioanalysis Bioequivalence Bioequivalence study composed Concentration COVID-19 Eclipse electrospray ionization Favipiravir flow rate healthy Human Human plasma isocratic LC–MS/MS Linear regression linearity m/z mass spectrometer methanol pharmacokinetic plasma sample positive protein precipitation pumped pyrazinamide quantification SARS-CoV-2 SARS-CoV-2 virus simple Treatment US-FDA Volunteer volunteers was used [DOI] 10.1016/j.jpba.2021.114057 PMC 바로가기 [Article Type] Article