Current Evidence of 2019 Novel Coronavirus Disease (COVID-19) Ocular Transmission: A Systematic Review and Meta-AnalysisReview Article Published on 2020-10-242022-10-27 Journal: BioMed Research International [Category] COVID-19, [키워드] 95% confidence interval CIs Cochrane Library conjunctival COVID-19 COVID-19 patient current diagnosed Evidence evidence of indicated initial symptom itching less medRxiv Meta-analysis novel objective ocular participant Patient performed positive rate Prevalence prevalence rate Primary outcome proportion Rate reported Result review secretion swab sample swab samples Symptom systematic review Transmission was done were expressed [DOI] 10.1155/2020/7605453 PMC 바로가기 [Article Type] Review Article
Current Evidence of 2019 Novel Coronavirus Disease (COVID-19) Ocular Transmission: A Systematic Review and Meta-AnalysisReview Article Published on 2020-10-242022-10-27 Journal: BioMed Research International [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] 95% confidence interval CIs Cochrane Library conjunctival COVID-19 COVID-19 patient current diagnosed Evidence evidence of indicated initial symptom itching less medRxiv Meta-analysis novel objective ocular participant Patient performed positive rate Prevalence prevalence rate Primary outcome proportion Rate reported Result review secretion swab sample swab samples Symptom systematic review Transmission was done were expressed [DOI] 10.1155/2020/7605453 PMC 바로가기 [Article Type] Review Article
Impact of COVID-19 outbreak on the mental health status of undergraduate medical students in a COVID-19 treating medical college: a prospective longitudinal studyEpidemiology Published on 2020-10-162022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 95% confidence interval addition adjusted adjusted odds ratio Affect Anxiety appear average baseline Chennai conducted COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 patient COVID-19 testing DASS21 Depression Follow-up Gender Impact index India Interaction investigated item Logistic regression analysis longitudinal study mental health Mental health disorder p value pandemic Patient patients performed Pittsburgh Poor predictor Prevalence PSQI Quality questionnaire Result significant increase significantly Sleep sleep quality statistically significant stratified Stress stress level Stress Scale Stressor Symptom the mean Undergraduate medical students were expressed were recorded were used with COVID-19 [DOI] 10.7717/peerj.10164 PMC 바로가기 [Article Type] Epidemiology
Identification of a Membrane Binding Peptide in the Envelope Protein of MHV CoronavirusArticle Published on 2020-09-222022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Amino acid Antigen binding Cell cholesterol coding sequence coronavirus CoV CoVs distribution DPPC E protein Endoplasmic reticulum envelope envelope protein ERGIC expressing expression full-length function Giant Golgi GUV identification identify in silico insect cells intestinal mammal mammalian membrane MHV mouse mutant Neurological disease peptide peptides positive predicted Replication RNA virus sphingomyelin tested Vesicle virus were expressed wild type [DOI] 10.3390/v12091054 PMC 바로가기 [Article Type] Article
Chinese herbal medicine for COVID-19: Current evidence with systematic review and meta-analysisReview article Published on 2020-09-012022-10-05 Journal: Journal of integrative medicine [Category] SARS, 신약개발, [키워드] 95% CI 95% confidence interval Adults adverse event adverse events Analysis C-reactive protein Care changes in China Chinese Chinese herbal medicine CHM Cochrane Library collected Computed tomography contagious Continuous control group Controlled trial Course COVID-19 COVID-19 cases criteria CRP current database disease evaluator Evidence Follow-up Google Scholar hazard ratio help IMPROVE Inflammatory inflammatory markers information Infrastructure life-threatening lung CT scan marker Meta-analysis New coronavirus objective Odds ratio outcome Participants Patient peer-reviewed Pneumonia Primary outcome Randomized controlled trial RCT RCTs Result risk risk of bia SARS-CoV-2 screened searched secondary SMD standard care standardized mean difference Study design Symptom systematic review therapy time-to-event analysis Traditional Chinese medicine treat Treatment treatment group Treatment outcome was used were expressed were recorded [DOI] 10.1016/j.joim.2020.07.008 [Article Type] Review article
Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysisOriginal Paper Published on 2020-08-272022-10-29 Journal: IJC Heart & Vasculature [Category] COVID-19, [키워드] 95% confidence interval 95%CI ACEi/ARB acute lung injury acute respiratory distress syndrome all-cause mortality Analysis angiotensin-converting enzyme inhibitor Angiotensin-receptor blocker animal ARB association blocker Collection core coronavirus COVID-19 disease COVID-19 infection disease severity enzyme estimate evaluate Evidence facilitate GRADE framework higher risk hypertensive patient Infection inhibitor Meta-analysis moderate Mortality mortality risk objective Odds ratio patients with COVID-19 performed Positive test potential benefit PsycINFO Random-effects meta-analysis required Result risk risk of COVID-19 robust SARS-CoV-2 searched severe COVID-19 disease significant decrease Stage suggested the disease the SARS-CoV-2 Web of Science were expressed [DOI] 10.1016/j.ijcha.2020.100627 PMC 바로가기 [Article Type] Original Paper
SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosisResearch Published on 2020-07-142022-10-28 Journal: Respiratory Research [Category] COVID-19, SARS, [키워드] ACE2 activate acute lung injury acute respiratory syndrome ADAM17 Affect AGT angiotensin-converting enzyme 2 assist bind binding bioinformatic analysis cellular receptor change cleaved connective tissue coronavirus COVID-19 CTGF dataset disease domain driver endothelial enzyme epithelial cell FN1 growth factor host cells human epithelial cell human lung induce Lung epithelial cells Lung fibrosis lung tissue mechanism metalloproteinase mRNA pandemic disease patients promote Protein protein expression Result SARS-CoV-2 SARS-COV-2 infection specific treatment TGFB1 Tissue Inhibitor TMPRSS2 transcriptional transmembrane serine protease Vascular VEGF viral entry were expressed were measured [DOI] 10.1186/s12931-020-01445-6 PMC 바로가기 [Article Type] Research
LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2Virus-Cell Interactions Published on 2020-07-082022-10-30 Journal: Journal of Virology [Category] COVID-19, MERS, [키워드] A549 cell ADAP2 adaptive immune responses Analysis Antigen Antiviral Cell cell line cell tropism cells cellular Contact Control coronavirus Coronavirus infection CoV CoV infection Critical determinant domain ectopic expression Efficiency effort expand expression facilitate Factor Fever growth HCoV-OC43 hepatoblastoma HepG2 HepG2 cells homology Host host cell host range Human human coronavirus human coronaviruses Human immunodeficiency virus identification IFITM3 IFITMs immune Immunopathogenesis Including Infection influenza A virus inhibited knockdown LY6E lymphocyte mechanism modulate neutralized overexpression pandemic Pathogenesis Protein Proteins reported restriction factor SARS-CoV-2 serine protease TMPRSS2 significantly significantly higher significantly increased Spike protein susceptibility susceptible transmembrane Treatment variety viral entry virus virus entry viruses were expressed while [DOI] 10.1128/JVI.00562-20 PMC 바로가기 [Article Type] Virus-Cell Interactions
Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirusArticle Published on 2019-12-062022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Amino acid Antibody Response Antisera C-terminal domain coronavirus CTD defined E. coli effective effective therapy Epitope region expression fluorescent Host identification immunodominant in vitro in vivo Infection inhibit mice N-terminal domain neutralization Neutralization assay Neutralizing Neutralizing antibodies neutralizing antibody NTD Porcine deltacoronavirus porcine deltacoronavirus (PDCoV) produced Protein Recombinant protein Region S protein S1 subunit S2 subunit spike glycoprotein the S protein the S1 subunit Transmission Vaccine Vaccines Virus neutralization were expressed [DOI] 10.1016/j.virusres.2019.197834 PMC 바로가기 [Article Type] Article
Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in EgyptResearch Article Published on 2019-02-112022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] analyses avirulent bronchitis cause chick circulating circumvent clinical disease Clinical sign comparable Complete develop development disease Express expressing growth IBV immunofluorescence in vitro Infectious Bronchitis Virus Lineage live-attenuated vaccine Middle East mutate newcastle disease virus parental prevalent provided recombine reduced reduction in resulting S glycoprotein S protein S protein expression significantly Single-dose SPF strain supplementary material tracheal vaccination Vaccine vaccine candidate variant viral shedding virulent virus viruses were expressed white wild type [DOI] 10.1186/s13567-019-0631-5 PMC 바로가기 [Article Type] Research Article