Cellular interferon-gamma and interleukin-2 responses to SARS-CoV-2 structural proteins are broader and higher in those vaccinated after SARS-CoV-2 infection compared to vaccinees without prior SARS-CoV-2 infectionArticle Published on 2022-10-172022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] assays BNT162b2 BNT162b2 vaccine class correlated demonstrated develop dose doses epitope exhibited Frequency greater healthcare worker healthy IFN-γ IgG response IL-2 IL2 Immunity individual infected with SARS-CoV-2 Infection Interferon-gamma interleukin-2 magnitude Moderna mRNA-1273 vaccine mononuclear cell mRNA-1273 N and M nine participant Participants PCR testing peptide Peripheral blood Pfizer-BioNTech positive Post-infection Proteins proteome repeated responders response responses against robust S glycoprotein S1 and S2 S2 subunit SARS-CoV-2 SARS-COV-2 infection structural protein subunit subunits T cell response T-cell Response the SARS-CoV-2 uninfected vaccination vaccinee was determined were expressed with COVID-19 [DOI] 10.1371/journal.pone.0276241 PMC 바로가기
The impact of vaccine hesitation on the intentions to get COVID-19 vaccines: The use of the health belief model and the theory of planned behavior modelArticle Published on 2022-10-142022-11-16 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] Affect affecting conducted covariate COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines Critical cross-sectional Factor Factors group HBM HBM (health belief model) Health Healthcare provider help Intention Intervention MOST Multiple linear regression perceived benefit proportion receive recruited risk Self-efficacy Standard deviation survey platform T-tests the vaccine TPB (theory of planned behavior) vaccinated against COVID-19 vaccination vaccination intention vaccination intentions Vaccine vaccine hesitation. variant were expressed were used [DOI] 10.3389/fpubh.2022.882909 PMC 바로가기
Early Lung Ultrasound Findings in Patients With COVID-19 Pneumonia: A Retrospective Multicenter Study of 479 PatientsArticle Published on 2022-10-012022-11-15 Journal: Journal of Ultrasound in Medicine [Category] COVID19(2023년), SARS, 진단, [키워드] Accuracy acute respiratory syndrome categorical variable chest X-ray consolidation continuous variable coronavirus coronavirus disease COVID COVID negative patient COVID-19 CXR Department diagnosed Diagnosis diagnostic distress Emergency enrolled evaluate Fever finding interstitial lung Lung ultrasound median molecular molecular test MOST multicenter multicenter study normal Patient patient cohort percentage performed Physicians Pneumonia point of care point-of-care positive presenting radiologic radiologist regions Retrospective study SARS-CoV-2 Sex standard error Ultrasound was performed were expressed White blood cell with COVID-19 [DOI] 10.1002/jum.15944 PMC 바로가기
Estimating deaths averted and cost per life saved by scaling up mRNA COVID-19 vaccination in low-income and lower-middle-income countries in the COVID-19 Omicron variant era: a modelling studyArticle Published on 2022-09-132022-11-16 Journal: BMJ Open [Category] SARS, 변종, [키워드] Analysis conducted country COVID-19 COVID-19 vaccination COVID-19 vaccine death deaths distribution dose Effectiveness effort epidemiological estimate expected mortality fatality Health health economics Infection Lower magnitude mRNA mRNA vaccine omicron outcome parameter potential benefit Public public health SARS-CoV2 Scaling sensitivity analysis Spread statistical vaccination Vaccine variant were expressed while [DOI] 10.1136/bmjopen-2022-061752 PMC 바로가기
Wild type and variants of SARS-COV-2 in Parisian sewage: presence in raw water and through processes in wastewater treatment plantsArticle Published on 2022-09-012022-11-16 Journal: Environmental science and pollution research inter [Category] SARS, 변종, 치료기술, [키워드] Concentration correlation COVID-19 Digital digital PCR E484K Efficiency Epidemic evaluate France French incidence rate indicated investigation L452R Log reduction N1 gene Outbreaks performed plant polymerase chain potential risk public health reduced reducing reported RNA SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA copy Surveillance the SARS-CoV-2 Treatment variant variants of concern wastewater wastewater surveillance were expressed WWTPs [DOI] 10.1007/s11356-022-22665-x PMC 바로가기
Structural investigations of proteins encoded by SARS-CoV-2Article Published on 2022-09-012022-11-16 Journal: FEBS Open Bio [Category] SARS, 변종, 유전자 메커니즘, [키워드] antibodies articles bases categories cellular cleaved commenced coronavirus COVID COVID-19 pandemic cysteine proteases described ENCODE Evolution example expressed Final Genome include knowledge MN908947.3 molecular mechanism other coronaviruses pandemic polyprotein positive-sense Protein protein structure purified reported Research ribonuclease RNA genome RNAs SARS-CoV-2 selected sequenced single-stranded small molecule drugs Spike protein structural property the disease the spike protein translation Vaccines variant viral transcript were expressed [DOI] 10.1002/2211-5463.13465 PMC 바로가기
Lasting SARS-CoV-2 specific IgG Antibody response in health care workers from Venezuela, 6 months after vaccination with Sputnik VArticle Published on 2022-09-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 진단, [키워드] antibody antibody unit average Binding antibody units or BAU/ml Cohort COVID-19 COVID-19 infection ELISA enrolled evaluated geometric mean concentration GMC Health care worker hospital Humoral immunity hybrid Hybrid COVID-19 immunity IgG IgG antibodies IgG antibody IgG level in vitro infection with SARS-CoV-2 information international unit International units or IU/ml naïve naïve subjects Neutralizing activity nucleocapsid protein (NP) Protein provided RBD RBD binding RBD binding inhibition assay receiving receptor binding domain (RBD) SARS-CoV-2 second dose Sputnik V vaccine subject vaccination Vaccine Venezuela were expressed were measured wild-type [DOI] 10.1016/j.ijid.2022.06.008 PMC 바로가기
Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein UbiquitinationArticle Published on 2022-08-292022-11-16 Journal: Medical science monitor : international medical jo [Category] 유전자 메커니즘, [키워드] Analysis ASB16 biological process Cell Characteristics Cluster conducted core gene COVID-19 COVID-19 pandemic DEGs detect differentially expressed gene enrichment evaluate expressed facilitate FBXO11 FOXA1 FOXC1 functional GATA2 Gene expression analysis Genes healthy controls hsa-miR-1-3p identify Interaction ITCH macrophages miRNA molecular mononuclear cell Patient performed peripheral Peripheral blood platform progression protein ubiquitination protein-protein interaction regulate Regulating Regulatory response RNA sequencing RNF130 severe COVID-19 signaling pathways single-cell transcription factors Transcriptome TRIM21 UBE2J1 was used were expressed YY1 [DOI] 10.12659/MSM.937532 PMC 바로가기
Emerging threat of drug-resistant tuberculosis and trends in the era of COVID-19: A descriptive study from northwestern NigeriaResearch article Published on 2022-08-012022-10-05 Journal: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases [Category] 치료기술, [키워드] Cohort COVID-19 COVID-19 pandemic drug Drug-resistant TB drug-resistant tuberculosis drug-sensitive effort Frequency hospital Mycobacterium tuberculosis Nigeria Patient percentages question reported Result Surveillance susceptibility Treatment Tuberculosis tuberculous were expressed [DOI] 10.1016/j.jctube.2022.100319 [Article Type] Research article
Human Intramuscular Hyperimmune Gamma Globulin (hIHGG) Anti-SARS-CoV-2-Characteristics of Intermediates and Final Product인간 근육내 과면역 감마 글로불린(hIHGG) 항-SARS-CoV-2-중간체 및 최종 제품의 특성Article Published on 2022-06-172022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] anti-N antibodies anti-RBD anti-SARS-CoV-2 antibody Antibody titer Concentration convalescent convalescent plasma COVID-19 defined determine enzyme Final four-parameter nonlinear regression Gamma gamma globulin Globulin Human human intramuscular hyperimmune gamma globulin anti-SARS-CoV-2 (hIHGG anti-SARS-CoV-2). hyperimmune IgA IgG IgM immunoassay inactivated inactivation intermediate intramuscular material NAb Neutralization assay neutralization titer neutralizing antibody plasma product pseudovirus Result Sample SARS-CoV-2 SARS-CoV-2 S protein significantly stability undetectable was reduced were expressed [DOI] 10.3390/v14061328 PMC 바로가기 [Article Type] Article