Playing around the anaerobic threshold during COVID-19 pandemic: advantages and disadvantages of adding bouts of anaerobic work to aerobic activity in physical treatment of individuals with obesityCOVID-19 전염병 동안 혐기성 역치 주변에서 놀기: 비만 환자의 물리적 치료에서 유산소 활동에 무산소 운동을 추가하는 것의 장점과 단점Review Published on 2021-05-282022-09-10 Journal: Acta Diabetologica [Category] MERS, SARS, 치료기술, [키워드] Adding aerobic Aerobic exercise aims anaerobic Anaerobic threshold Blood body mass cardiorespiratory catecholamine Comorbidities Comorbidity Complication concerning COVID-19 COVID-19 pandemic debate diet disadvantage Diseases Disposal Effect exercise Final growth hormone High-intensity IMPROVE increase in individual intensity Lactate lactic acid limit management metabolism methodology milestone moderate normal weight number of comorbidity obesity overcome performed physical physical activity Physical exercise potential benefit potential benefits Prognosis re-evaluation reduction rehabilitation related diseases respiratory Result subject systemic threshold Treatment Variation Ventilation ventilatory [DOI] 10.1007/s00592-021-01747-1 PMC 바로가기 [Article Type] Review
Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity비만이 있는 COVID-19 환자에서 염증성 사이토카인과 다기관 기능 장애 사이의 차별적 연관성Research Article Published on 2021-05-262022-09-10 Journal: PLoS ONE [Category] SARS, 바이오마커, 유전자 메커니즘, [키워드] Admission association BMI body mass body mass index categories chemokines clinical implications Computed tomography Computed tomography scans consolidation correlated COVID-19 patient cytokine cytokine levels Cytokines Endothelial dysfunction endothelial marker Endothelial markers flow cytometric function ground-glass opacity groups hepatic steatosis Hospitalization Immune cell immune parameter independent independent of Infection Inflammatory cytokine Inflammatory cytokines intensive care lesion liver lung damage mechanism Multiorgan dysfunction normal weight obesity on admission Patient patients patients with obesity performed physiopathological mechanism Prospective Study quantified renal reveal SARS-CoV-2 SARS-COV-2 infection severity steatosis subset the SARS-CoV-2 tomography was performed zenith [DOI] 10.1371/journal.pone.0252026 PMC 바로가기 [Article Type] Research Article
Equity in vaccine trials for higher weight people? Protocol for a rapid review of inclusion and exclusion criteria for higher weight people in clinical trials for COVID-19더 높은 체중의 사람들을 위한 백신 실험의 형평성? COVID-19에 대한 임상 시험에서 고체중 환자에 대한 포함 및 제외 기준의 신속한 검토를 위한 프로토콜Article Published on 2021-05-252022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] Analysis body mass body mass index Care clinical clinical trial clinical trials country COVID-19 COVID-19 susceptibility COVID-19 vaccine trial COVID-19 vaccine trials data extraction described Descriptive analysis determine disease disease severity dose Efficacy Ethical approval Ethics evaluate exclusion criteria guidelines Inclusion inclusion and exclusion criteria increased risk indicated individual ISRCTN minimum outcome Participation Population PROSPERO protocol protocols protocols & public health recruit reduce Registered registration number required risk factor risk of bia Screening study group Subgroup analyses subgroup analysis subset susceptibility the disease the WHO Trial trial protocol vaccine platform vaccine trial [DOI] 10.1136/bmjopen-2021-050114 PMC 바로가기 [Article Type] Article
Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release AssaySARS-CoV-2 감염 후 구조 단백질의 광범위한 T 세포 표적화: 자동화된 인터페론 감마 방출 분석을 사용한 T 세포 반응성의 높은 처리량 평가Immunology Published on 2021-05-202022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료법, [키워드] Antibody titer Antigen antigens approach assessment automated body mass body mass index breadth C-terminus characteristic comparable confirmed case confirmed cases Control control subjects convalescent coronavirus disease Coronavirus disease 2019 correlated COVID-19 days post infection Elecsy Elecsys facilitate followed by fresh whole blood Gamma groups high accuracy high through put IgG immune response immune responses Infection interferon gamma interferon gamma release assay (IGRA) large cohort less magnitude membrane nucleocapsid PCR positive Protein reactivity Release Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SCT seropositive seropositive individual Seropositivity Sex significantly specific antibodies structural protein structural proteins subject T cell T cell response T cell responses T cells targeting targets tested throughput virion virus was performed were assessed Whole blood [DOI] 10.3389/fimmu.2021.688436 PMC 바로가기 [Article Type] Immunology
Dietary Habits before and during the COVID-19 Epidemic in Selected European Countries일부 유럽 국가에서 COVID-19 전염병 이전과 동안의 식습관Clinical Trial Published on 2021-05-162022-08-13 Journal: Nutrients [Category] SARS, 임상, [키워드] affected aggravation alcohol alcohol consumption body mass body weight changed changes changes in condition conducted confinement period Consequences contribute country COVID-19 COVID-19 pandemic cross-sectional dairy dietary habit dietary habits distribution Europe European food Frequency Health lockdown lockdowns media obesity observational study pandemic physical activity physical activity level physical activity levels Poland problem questionnaire reflected resulting retrospective second wave shelf life social media sweet turn unemployment United Kingdom working Working conditions [DOI] 10.3390/nu13051690 PMC 바로가기 [Article Type] Clinical Trial
Continuous renal replacement therapy with the addition of CytoSorb cartridge in critically ill patients with COVID-19 plus acute kidney injury: A case-seriesCOVID-19와 급성 신장 손상이 있는 중환자에서 CytoSorb 카트리지를 추가하여 지속적인 신대체 요법: 사례 시리즈Article Published on 2021-05-012022-09-11 Journal: Artificial organs [Category] MERS, SARS, 바이오마커, [키워드] 95% CI acute kidney Acute kidney injury acute respiratory distress acute respiratory distress syndrome addition Admission AKI Analysis analyzed Antibiotics anticoagulation APACHE ARDS arterial pressure assessment body mass body mass index C-reactive protein cartridge chronic Concentration Continuous Continuous renal replacement therapy continuous renal replacement therapy with cytosorb COVID-19 COVID-19 patient Critically ill critically ill COVID-19 patients Critically ill patient CRRT CRS cutoff point Cytokine release syndrome Cytosorb D-dimers Duration enrolled ferritin function Hospital mortality Hydrocortisone hyperinflammation ICU ICU admission in-hospital mortality inflammatory biomarkers intensive care interferon interferon beta Interferon beta-1b interleukin interleukin-6 Lactate lactate dehydrogenase life-threatening lymphocyte Lymphocyte count lymphocyte counts male mechanical ventilation Mortality nonsurvivors organ function oxygen Oxygenation PaO Patient Physiology predicted prone positioning Prophylactic prophylactic anticoagulation provided Pulmonary emboli renal replacement therapy replacement therapy respiratory distress Respiratory distress syndrome retrospective ribavirin Safe Sepsis Septic shock Shock Side effect SOFA SOFA scores survivor Survivors syndrome therapy Thromboembolism Ventilation were recorded with COVID-19 [DOI] 10.1111/aor.13864 PMC 바로가기 [Article Type] Article
Characteristics and impact of cardiovascular comorbidities on coronavirus disease 2019 in women: A multicentre cohort study여성의 코로나바이러스 질병 2019에 대한 심혈관 질환의 특성 및 영향: 다기관 코호트 연구Observational Study Published on 2021-05-012022-09-11 Journal: Archives of cardiovascular diseases [Category] 바이오마커, 임상, [키워드] 95% CI 95% confidence interval adjusted Admission BNP body mass body mass index cardiovascular comorbidities cardiovascular comorbidity cardiovascular diseases Chronic kidney disease cohort study Concentration consecutive patient Coronary artery Coronary artery disease coronavirus disease Coronavirus disease 2019 COVID-19 death English Facteurs de risque female Femmes French hazard ratio heart failure hospital Hospitalized IC95 % In-hospital death Infection intensive care intensive care unit Kidney disease less lower risk men multicentre NT-pro-BNP Older outcome outcomes Patient patients patients hospitalized peptide prevalent Primary outcome prohormone remained reported Résultats Risk factors SARS-CoV-2 Sex transfer troponin troponine with COVID-19 women [DOI] 10.1016/j.acvd.2021.04.002 PMC 바로가기 [Article Type] Observational Study
Immunoglobulin Response and Prognostic Factors in Repeated SARS-CoV-2 Positive Patients: A Systematic Review and Meta-Analysis반복 SARS-CoV-2 양성 환자의 면역글로불린 반응 및 예후 인자: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-04-302022-09-01 Journal: Viruses [Category] MERS, 진단, [키워드] age Analysis association BMI body mass body mass index Cohort studies cohort study COVID-19 disease course evaluate examined Factor first episode follow-up studies follow-up study Gender Hospitalization IgG IgG positivity IgM Immunoglobulin Immunoglobulin G immunoglobulin M immunoglobulin response Infection information initial male mean difference mean differences Meta-analysis Mild Odds ratio Odds ratios Patient Prognosis Prognostic factor Prognostic factors recovered patients repeated repositivity required response review risk factor Risk factors SARS-CoV-2 SARS-CoV-2 positivity severity systematic literature search Topic was performed [DOI] 10.3390/v13050809 PMC 바로가기 [Article Type] Meta-Analysis
Clinical characteristics of SARS-CoV-2 pneumonia diagnosed in a primary care practice in Madrid (Spain)마드리드(스페인)의 1차 진료에서 진단된 SARS-CoV-2 폐렴의 임상적 특징Observational Study Published on 2021-04-292022-09-01 Journal: BMC Family Practice [Category] MERS, SARS, 임상, 진단, [키워드] age Bilateral bilateral pneumonia Blood blood test body mass body mass index C-reactive protein Chain Reaction Characteristics chest X-ray clinical Clinical characteristics Clinical data clinical manifestation clinical manifestations collected Comorbidities Complication cough COVID-19 Day death described diabete diabetes diagnosed Diagnosis diagnostic test diagnostic tests dyslipidaemia Dyspnoea Electronic health record Electronic health records female Fever Gastrointestinal disturbances group Hospitalised patients hypertension Infection lymphocyte Lymphocytes MOST Nasopharyngeal swab occurred outcome Patient patients with SARS-CoV-2 Physical examination Pneumonia pneumonias prevalent primary care Pulmonary embolism pulse oximetry Result Retrospective study reverse transcriptase reverse transcriptase-polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia Spain Standard deviation stratified supplementary material the mean the SARS-CoV-2 [DOI] 10.1186/s12875-021-01430-y PMC 바로가기 [Article Type] Observational Study
Prevalence, clinical features, and outcomes of SARS-CoV-2 infection in pregnant women with or without mild/moderate symptoms: Results from universal screening in a tertiary care center in Mexico City, Mexico경증/중등도 증상이 있거나 없는 임산부에서 SARS-CoV-2 감염의 유병률, 임상 양상 및 결과: 멕시코 멕시코시티에 있는 3차 의료 센터의 보편적 선별 검사 결과Research Article Published on 2021-04-222022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] 95% CI Admission age Asymptomatic baseline Birth Body body mass body mass index both group both groups Care case-control study Clinical features community transmission complications condition consequence COVID-19 COVID-19 test death discharged Diseases feature gestational age highest highlight Hospitalization Illness severity index Infant mass maternal age Maternal death median Mexico City mild symptoms moderate disease mother Neonate Neonates NICU nine no differences number of infected Obstetric outcome outcomes Patient percentage positive preeclampsia Pregnancy pregnant women prevalence of COVID-19 proportion Quantitative Quantitative RT-PCR reported Result retrospective risk factor Risk factors RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test severe COVID-19 Severity of infection test result the patient Transmission women [DOI] 10.1371/journal.pone.0249584 PMC 바로가기 [Article Type] Research Article