A Narrative Review of the Evidence for Variations in Serum 25-Hydroxyvitamin D Concentration Thresholds for Optimal HealthReview Published on 2022-02-022022-10-31 Journal: Nutrients [Category] COVID-19, COVID19(2023년), [키워드] 25-hydroxyvitamin D all-cause mortality rate Alzheimer’s disease approach baseline benefit Cancer cardiovascular disease Care cause Concentration concentrations COVID-19 death diabetes dose drugs ecological Effect Evidence Health hypertension involved mechanisms mendelian randomization Mendelian randomization studies narrative observational studies outcome participant performed raising Randomized controlled trial RCT RCTs reduction in review serum serum 25-hydroxyvitamin D Study design Support threshold type 2 diabete variety Vitamin D Vitamin D supplementation [DOI] 10.3390/nu14030639 PMC 바로가기 [Article Type] Review
Building knowledge of university campus population dynamics to enhance near-to-source sewage surveillance for SARS-CoV-2 detectionSARS-CoV-2 감지를 위해 근원지에서 가까운 하수 감시를 강화하기 위해 대학 캠퍼스 인구 역학에 대한 지식 구축Article Published on 2022-02-012022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] activity addressed arising Biomarkers building collected complementary Concentration concentrations confidence COVID-19 COVID-19 pandemic demonstrated England ENhance Epidemiology estimate Focusing help identify information knowledge management Near-to-source Normalisation outbreak pathogen transmission Population Population size populations provide provided Public health intervention Public health interventions SARS-CoV-2 SARS-CoV-2 detection shown significant difference significant differences subject Surveillance the SARS-CoV-2 triggering upstream Variability Variation wastewater Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2021.150406 PMC 바로가기 [Article Type] Article
An automated chemiluminescent immunoassay (CLIA) detects SARS-CoV-2 neutralizing antibody levels in COVID-19 patients and vaccinees자동화된 화학발광 면역분석(CLIA)은 COVID-19 환자와 백신 수혜자의 SARS-CoV-2 중화 항체 수준을 감지합니다.Article Published on 2022-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Analysing Antigen antigens automated can be used characteristic chemiluminescent immunoassay CLIA Concentration concentrations convalescent patient Coronavirus-2 COVID-19 patient cut-off value detect Diagnosis domain ectodomain Effectiveness evaluate evaluated groups half-life healthy individual indicated Infection linear mathematical mathematical model Mathematical models Microneutralization test MNT NAb titer NAb titers neutralizing antibody positive Protective protocol R 2 RBD receiver operating characteristic receiver operating characteristic curve respiratory SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine sensitivity severe acute respiratory syndrome Coronavirus specificity tested Treatment Vaccine vaccinee vaccinees variable [DOI] 10.1016/j.ijid.2021.12.316 PMC 바로가기 [Article Type] Article
Open-source real-time quantitative RT-PCR-based on a RNA standard for the assessment of SARS-CoV-2 viral loadSARS-CoV-2 바이러스 부하 평가를 위한 RNA 표준 기반 오픈 소스 실시간 정량 RT-PCRResearch Article Published on 2022-01-282022-09-10 Journal: Memórias do Instituto Oswaldo Cruz [Category] SARS, 진단, 치료기술, 치료제, [키워드] (RdRp 2019-nCoV assay acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach clinical samples Combination Concentration concentrations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 testing demonstrated detection diagnostics Efficiency evaluated highest identify IMPROVE individual Infection molecular nasopharynx oropharynx plasma samples primer primer pair Quantitative RdRP reaction real-time polymerase chain reaction respiratory reverse primer Reverse transcriptase polymerase chain reaction RNA RNA-dependent RNA polymerase RT-PCR RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 viral load selected sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity target gene Target genes tested Viral Viral load was performed [DOI] 10.1590/0074-02760210237 PMC 바로가기 [Article Type] Research Article
Transmitted Fetal Immune Response in Cases of SARS-CoV-2 Infections during PregnancyArticle Published on 2022-01-192022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age analyzed anti-SARS-CoV-2 antibodies CD3 CD3+ CD34 CD4 CD8 cell count cellular immunity change Concentration concentrations correlation COVID-19 and pregnancy diagnosis of SARS-CoV-2 Effect fetal fetal immune system fetal lymphocyte subsets humoral IFN-γ IgG IgG and IgM IgM antibody IL6 immune response Immunity Infection Inflammatory response information iNKT interleukin interleukin 6 mononuclear cell Newborn Placenta placental Placentas Pregnancy pregnant women recruited Research response RNA SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection significantly higher study period subset T cell the SARS-CoV-2 virus transfer transmitted umbilical cord blood undetectable Viral RNA [DOI] 10.3390/diagnostics12020245 PMC 바로가기 [Article Type] Article
Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 InfectionArticle Published on 2022-01-192022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] ACE protein expression ACE2 ACE2 activity ACE2 expression ACE2 mRNA expression activity analysed Caco-2 Cell Concentration concentrations COX2 demonstrated drug enzyme Etoricoxib expression Flurbiprofen had no human cell ibuprofen in vitro in vivo influence investigated lung mice no effect non-steroidal anti-inflammatory drug NSAIDS pandemic Paracetamol receptor reduced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severity of COVID-19 significantly surface protein tissue treated viral entry [DOI] 10.3390/ijms23031049 PMC 바로가기 [Article Type] Article
Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates96웰 플레이트에서 친화성 막을 사용하여 몇 분 안에 SARS-CoV-2에 대한 Trastuzumab 및 항체 정량화Article Published on 2022-01-182022-09-12 Journal: Analytical Chemistry [Category] SARS, 진단, [키워드] 96-well plate Activation affinity Analysis average binding calibration curve Combination concentrations effective fluorescence intensity group human serum mAb mAbs membrane membranes microplate reader minute monoclonal antibody occur passage Patient peptide Plate Protein quantitation Research SARS-CoV-2 secondary antibody serum Spike protein the SARS-CoV-2 therapeutic Trastuzumab Treatment Variability [DOI] 10.1021/acs.analchem.1c03654 PMC 바로가기 [Article Type] Article
Could Lower Testosterone in Older Men Explain Higher COVID-19 Morbidity and Mortalities?Review Published on 2022-01-152022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] age aging Anti-inflammatory benefit calcium regulation Cell cellular Concentration concentrations COVID-19 COVID-19 pandemic death decrease demonstrated diminishes diverse protein Epidemics facilitate Health healthy homeostasis immunological inflammaging involved lack Lower males mechanism men Middle East modulate modulation observation Older outcome Protein regulate Replication SARS-CoV SARS-CoV-2 syndrome Testosterone the SARS-CoV-2 virus tissue viral replication viruses [DOI] 10.3390/ijms23020935 PMC 바로가기 [Article Type] Review
Photodynamic Inactivation of Human CoronavirusesArticle Published on 2022-01-082022-10-28 Journal: Viruses [Category] COVID-19, [키워드] absence Antiviral antiviral activity Antiviral effect antiviral property assays Betacoronavirus concentrations coronavirus CoVs cultured cell damaged demonstrated digestion dose-dependent manner doses emodin expand experiments HCoV-229E HCoV-OC43 herpes simplex Human human cells human coronavirus inactivation inhibited lentivirus Local microorganisms natural product oxygen PDI photodynamic inactivation photosensitizer PhytoQuin prevented Protein pseudotyped reactive oxygen specy Replication RNase ROS S protein SARS-CoV-2 spike susceptible the SARS-CoV-2 Viral RNA virus viruses [DOI] 10.3390/v14010110 PMC 바로가기 [Article Type] Article
Intervention of an Upgraded Ventilation System and Effects of the COVID-19 Lockdown on Air Quality at Birmingham New Street Railway StationArticle Published on 2022-01-052022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Air pollution approaches average carbon carbon monoxide comparison Concentration concentrations COVID-19 COVID-19 pandemic decrease diesel trains Effect Effectiveness emission enclosed railway station IMPROVE intensities Intervention matter Monoxide New nitrogen dioxide occupational Particulate Particulate matter platform produced Public Quality Railway recorded reduction reduction in Standard Station Street System upgraded ventilation system Ventilation [DOI] 10.3390/ijerph19010575 PMC 바로가기 [Article Type] Article