Detection of anti-Histoplasma capsulatum antibodies and seroconversion patterns in critically ill patients with COVID-19: An underdiagnosed fungal entity complicating COVID-19?COVID-19에 감염된 중환자에서 항히스토플라스마 캡슐화 항체 및 혈청전환 패턴의 검출: COVID-19를 복잡하게 만드는 과소 진단된 곰팡이 개체?Article Published on 2022-03-042022-09-11 Journal: Medical mycology [Category] MERS, SARS, 진단, 치료기술, [키워드] AIDS analyzed antibody Antibody titer Antibody titers Awareness baseline Bearing Buenos Aire Buenos Aires candidiasis classical clinician Co-infection COVID-19 pneumonia COVID-19-associated mycoses Critically ill Critically ill patient critically ill patients death detection Diagnosis died Endemic endemic area endemicity evaluated FIVE fungal fungal disease fungal infections fungus help Histoplasma Histoplasma capsulatum Histoplasmosis HIV/AIDS Hospitalized house ICU IgG antibodies IgG antibody in-house ELISA increased risk infections invasive Invasive pulmonary aspergillosis mind morbidity morbidity and mortality Mycoses Patient positive Prevent pulmonary aspergillosis reduce respiratory Respiratory failure Respiratory function risk risk factor SARS-CoV-2 Sepsis sera Seroconversion seronegative seropositive serum sample serum samples severe COVID-19 Severe COVID-19 pneumonia severe respiratory failure specific IgG antibodies Treatment with COVID-19 worsening [DOI] 10.1093/mmy/myac012 PMC 바로가기 [Article Type] Article
A qualitative study of reinforcement workers’ perceptions and experiences of working in intensive care during the COVID-19 pandemic: A PsyCOVID-ICU substudyRandomized Controlled Trial Published on 2022-03-042022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] analyzed average age COVID COVID-19 Critically ill patient difficulty distress had no healthcare healthcare worker hospital ICU ICUs individual intensive care investigated lack management Nurses pandemic participant performed random recorded Result suffered thematic analysis transcribed unique [DOI] 10.1371/journal.pone.0264287 PMC 바로가기 [Article Type] Randomized Controlled Trial
Secondary infection in COVID-19 critically ill patients: a retrospective single-center evaluationCOVID-19 중환자 환자의 2 차 감염 : 후 향적 단일 센터 평가Observational Study Published on 2022-03-022022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 임상, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus administration of corticosteroid Admission adult COVID-19 patient aggravate Bacteremia Bacterial infection Bacterial infections Belgium bloodstream infection Bloodstream infections catheter caused cocci Combination coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients Culture cultures cumulative Cumulative Dose database develop diabetes Diabetes Mellitus dose eligible for inclusion Gender gram group higher risk highest ICU identify Immunosuppression incidence increased risk Infection intensive care intensive care unit Observational cohort study pathogen Pathogens Patient patients Pneumonia proportion Research Result resulting retrospective retrospective observational cohort study risk risk factor risk of death SARS-CoV-2 secondary bacterial infection Secondary bacterial infections Secondary infection secondary infections secondary pneumonia Sepsis severe acute respiratory syndrome Coronavirus severity severity of illness single-center supplementary material susceptible virus Virus Disease was performed [DOI] 10.1186/s12879-022-07192-x PMC 바로가기 [Article Type] Observational Study
Signals were broadly positive for months, but never definitive: the tocilizumab story신호는 몇 달 동안 대체로 긍정적이었지만 결코 확정적이지 않았습니다: tocilizumab 이야기Review Published on 2022-03-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] SARS, 신약개발, 진단, [키워드] accounted analysed appear cohorts Combination conducted confidence interval coronavirus disease COVID COVID-19 COVID-19 disease Critical Critically ill patient death Dexamethasone discrepant results dosage effect size Effectiveness Efficacy Evidence Evidence-based medicine exhibiting Factors heterogeneous Hypothesis in vitro Inclusion inclusion criteria information Invasive mechanical ventilation large sample Meta-analysis MOST observation observational studies observational study occurred pandemic pathway patients treated positive prevented Propensity score Propensity score methods randomized trial RCT RCTs recommendations reduction in risk signal small sample size Standard of care TESEO Tocilizumab treat Treatment treatment guideline [DOI] 10.1016/j.cmi.2021.10.018 PMC 바로가기 [Article Type] Review
Association between tracheostomy timing and outcomes for older critically ill COVID-19 patients: prospective observational study in European intensive care unitsClinical Trial Published on 2022-03-012022-10-05 Journal: British journal of anaesthesia [Category] 임상, [키워드] 95% CI 95% confidence interval age Analysis association clinical Clinical outcome concerning Confirmed COVID-19 infection COVID-19 COVID-19 patient Critically ill Critically ill patient Europe European European country evaluate Evidence expected Final hazard ratio healthcare intensive care intensive care unit intensive care units intubation Invasive mechanical ventilation landmark analysis mechanical ventilation Mortality no difference Older outcome outcome assessment Patient patients patients with COVID-19 performed primary analysis prospective cohort study prospective observational study survival the timing tracheostomy Trial Variation was performed with COVID-19 [DOI] 10.1016/j.bja.2021.11.027 PMC 바로가기 [Article Type] Clinical Trial
Clinical outcomes of corticosteroids for COVID-19 patients at the National Center for Global Health and Medicine during the first wave of infectionsResearch article Published on 2022-03-012022-10-05 Journal: Respiratory investigation [Category] SARS, 임상, [키워드] acute respiratory syndrome Admission both groups caused center Characteristics clinical Clinical course Clinical efficacy collected data condition coronavirus Coronavirus disease 2019 Corticosteroid corticosteroid therapy Corticosteroids COVID-19 COVID-19 patient Critically ill patient Dexamethasone diagnosed with COVID-19 examined Fever First wave global health hospital ill patients Infection infections Japan medical record Medicine mortality rate no difference no statistical difference outbreak outcome Patient patients with COVID-19 polymerase chain Primary outcome reduced Result SARS-CoV 2 seven-category ordinal scale severely ill patient treated Treatment two group with COVID-19 [DOI] 10.1016/j.resinv.2021.11.001 [Article Type] Research article
Presence and clinical impact of human herpesvirus-6 infection in patients with moderate to critical coronavirus disease-19중등도에서 중증 코로나바이러스 질환-19 환자에서 인간 헤르페스바이러스-6 감염의 존재 및 임상적 영향Article Published on 2022-03-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Cancer cardiovascular diseases clinical impact Clinical outcome clinical outcomes Coinfection Coronavirus disease-19 COVID-19 COVID-19 patients Critical Critically ill Critically ill patient critically ill patients diabetes disease epidemiological studies evaluated Frequency hematological herpesvirus-6. HHV-6 HHV-6B Hospital admission Hospitalized Human immunocompromised individuals Immunosuppressed immunosuppressed patient Infection kidney transplant lupus erythematosus lymphopenia mechanisms medical records moderate Mortality nasopharyngeal sample Nasopharyngeal samples neurological manifestation not significant obesity patients patients with moderate pilot study positive Presence Prospective Study Sanger sequencing SARS-CoV-2 systemic lupus erythematosus therapeutic Viral viral reactivation [DOI] 10.1002/jmv.27392 PMC 바로가기 [Article Type] Article
Negative pressure therapy as a safe alternative in the treatment of massive subcutaneous emphysema in critically ill patients COVID-19Case report Published on 2022-03-012022-10-05 Journal: Heart & lung : the journal of critical care [Category] SARS, 치료법, [키워드] approach barotrauma Consensus Contagion COVID-19 COVID-19 pandemic Critical Critically ill patient described effective emphysema Health healthcare personnel increased risk infected patients intensive care intensive care units invasive Invasive mechanical ventilation male management Massive subcutaneous emphysema Minimally invasive techniques MSE Negative pressure Patient performed reducing respiratory infections retained Safe surgical therapeutic therapeutic efficacy therapy tissue treated Treatment Viral load [DOI] 10.1016/j.hrtlng.2022.01.006 [Article Type] Case report
Evaluation of bacterial agents isolated from endotracheal aspirate cultures of Covid-19 general intensive care patients and their antibiotic resistance profiles compared to pre-pandemic conditions코로나19 일반 중환자실 환자의 기관내 흡인 배양액에서 분리한 세균성 물질의 평가와 전염병 이전 상태와 비교한 항생제 내성 프로파일Article Published on 2022-03-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료기술, [키워드] Acinetobacter age amoxicillin Antibiotic resistance Antibiotics antimicrobial Antimicrobial stewardship Bacterial bacterial co-infection Candida cefepime Ceftazidime ciprofloxacin clavulanic acid clinical Clinical outcome colistin condition Course COVID-19 pandemic Critically ill Critically ill patient critically ill patients Culture cultures died ertapenem Escherichia coli evaluated Gender growth ICU imipenem increase increase in infected with SARS-CoV-2 intensive care intensive care follow-up intensive care patient intensive care unit Klebsiella pneumoniae levofloxacin meropenem microorganism more difficult Mortality no significant difference nosocomial Nosocomial pneumonia P. aeruginosa pandemic Patient patients hospitalized piperacillin piperacillin-tazobactam Pneumonia pneumoniae Prevalence prevalent profile Pseudomonas aeruginosa SARS-CoV-2 Secondary infection secondary infections shown significant difference Staphylococcus aureus statistically significant statistically significant difference strain Strains tazobactam the mean tigecycline tobramycin Treatment VAP Ventilator-associated pneumonia while [DOI] 10.1016/j.micpath.2022.105409 PMC 바로가기 [Article Type] Article
D-dimer, CRP, PCT, and IL-6 Levels at Admission to ICU Can Predict In-Hospital Mortality in Patients with COVID-19 PneumoniaResearch Article Published on 2022-02-282022-10-29 Journal: Oxidative Medicine and Cellular Longevity [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] age Belgrade Can center clinical Clinical outcome COVID-19 outbreak COVID-19 patients criteria Critically ill Critically ill patient CRP cutoff value D-dimer diagnosis of COVID-19 discharged disease effective female FEU for inclusion Health care hospital Hospitalization ICU identify IL-6 IMPROVE in-hospital death prediction in-hospital mortality intensive care unit Level log-rank test male management median age Mortality Patient patients died patients treated PCT predict predictor procalcitonin recognize Result retrospective cohort study ROC Curve statistically significant survival the Kaplan-Meier method Treatment was determined were used with COVID-19 [DOI] 10.1155/2022/8997709 PMC 바로가기 [Article Type] Research Article