Measuring the Outcomes of Maternal COVID-19-related Prenatal Exposure (MOM-COPE): study protocol for a multicentric longitudinal project산모의 COVID-19 관련 산전 노출 결과 측정(MOM-COPE): 다심적 종단 프로젝트를 위한 연구 프로토콜Article Published on 2020-12-312022-09-11 Journal: BMJ Open [Category] SARS, 유전자 메커니즘, [키워드] approved association behavioural Birth Cohort collected conception contribute coping strategies COVID-19 Critical depressive developmental DNA methylation during pregnancy Effect enrolled Epidemic Epigenetic Ethics ethics committee Europe exposure exposure to Health hotspot Infant Infants infection rate Interaction International Italy Maternal mechanism Mental mental health methodological Methylation mother National outcomes Pavia peer-reviewed perinatology Pregnancy prenatal programming protocol Psychological psychological status Psychological stress registration number Regulation respiratory Respiratory disease Result retrospective retrospective data risk saliva sample saliva samples sensitivity Spread Stress Study protocol Symptoms virus [DOI] 10.1136/bmjopen-2020-044585 PMC 바로가기 [Article Type] Article
Diagnostic Value of the Hypomethylation of the WISP1 Promoter in Patients with Hepatocellular Carcinoma Associated with Hepatitis B VirusArticle Published on 2020-12-012023-06-13 Journal: The Tohoku Journal of Experimental Medicine [Category] B형 간염, [키워드] Biomarker DNA methylation Hepatocellular carcinoma methylation-specific polymerase chain reaction. Wnt1-inducible signaling pathway protein 1 [DOI] 10.1620/tjem.252.297
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: Triggering a Lethal Fight to Keep Control of the Ten-Eleven Translocase (TET)-Associated DNA Demethylation?Review Published on 2020-11-302022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] accounted activities activity acute respiratory syndrome adjacent sequences affected bimodal binding site cellular children clinical symptom complex Control coronavirus coronavirus 2 correlation COVID-19 deregulation DNA DNA methylation enzyme Factor function Gene Expression high mortality higher risk homeostasis Host hypoxia in vitro In vitro studies inactivation include intestinal Keep lethal liver mortality rate neuronal Patient patients promoters proteasomal Protein regulated Regulation Regulatory respiratory responsible SARS-CoV-2 selective Symptom Symptoms TET TET enzymes TET2 translocase viral invasion virus inactivation women X chromosome Xist [DOI] 10.3390/pathogens9121006 PMC 바로가기 [Article Type] Review
Genomic, epigenomic, and immune subtype analysis of CTSL/B and SARS-CoV-2 receptor ACE2 in pan-cancer범암에서 CTSL/B 및 SARS-CoV-2 수용체 ACE2의 게놈, 후성유전체 및 면역 아형 분석Research Paper Published on 2020-11-302022-09-10 Journal: Aging (Albany NY) [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] ACE2 addition Analysis analyzed angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 association bioinformatics Cancer cathepsin cathepsin B cathepsin L Cell Cervical copy number COVID-19 CTSB CTSL CTSL/B Cystadenocarcinoma demonstrated DNA methylation endocervical enzyme epigenomic Gene Expression genetic alterations healthcare IFN-gamma immune International Methylation negative correlation ovarian overexpressed positive correlation potential risk present Prognosis protease receptor Result risk risk factor RNA expression SARS-coronavirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor serous Cystadenocarcinoma Society Squamous cell Squamous cell carcinoma stomach subtype upregulation urothelial carcinoma [DOI] 10.18632/aging.104147 PMC 바로가기 [Article Type] Research Paper
Chicken cecal DNA methylome alteration in the response to Salmonella enterica serovar Enteritidis inoculation살모넬라 엔테리티디스 접종에 대한 반응에서 닭 맹장 DNA 메틸롬 변화Research Article Published on 2020-11-232024-07-29 Journal: BMC Genomics [Category] 살모넬라증, [키워드] cecum chicken DNA methylation Salmonella enterica serovar Enteritidis Whole-genome bisulfite sequencing [DOI] 10.1186/s12864-020-07174-w PMC 바로가기 [Article Type] Research Article
Exposome and Immunity Training: How Pathogen Exposure Order Influences Innate Immune Cell Lineage Commitment and FunctionReview Published on 2020-11-112022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] Activation adaptive Alter antigen exposure caused Cell change characteristic commitment COVID-19 Critical cumulative deleterious effect dendritic cells disease DNA methylation dose Effect environmental exposure Epigenetic epigenetics exposome exposure function genetics Health Histone modification Host identify immune immune responses Immunity immunomodulatory IMPROVE increasingly individual Infection inflammatory disease influence Innate innate immune innate immune system Innate immunity key factor Lineage macrophages mechanism memory Monocytes morbidity Mortality NK cells non-specific phenotype Prevent Prophylactic Protective provide Research response SARS-CoV-2 shown subsequent Tolerance trained immunity vaccination [DOI] 10.3390/ijms21228462 PMC 바로가기 [Article Type] Review
A role of glycation and methylation for SARS-CoV-2 infection in diabetes?당뇨병에서 SARS-CoV-2 감염에 대한 당화 및 메틸화의 역할?Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 바이오마커, 진단, [키워드] ACE2 ACE2 expression adipose Adipose tissue affected Amino acid angiotensin Angiotensin II Angiotensin-converting enzyme angiotensin-converting enzyme 2 Biomarker blockers Cancer Comorbidity conditions COVID-19 demonstrated diabete diabetes DNA methylation enzyme Extracellular Glycation glycemic control high mortality rate human cells hydrogen hypertension IMPROVE insulin insulin resistance Interaction Intervention involved islet liver lysine Methylation muscle obesity observation outcome patients with diabete peripheral tissue peripheral tissues pharmacological treatments predict Protein RBD receptor Receptor binding domain Receptor Blockers residue responsible risk SARS-CoV-2 SARS-COV-2 infection suggested T2D target tertiary structure the SARS-CoV-2 tissue treated Trigger triggers type-2 diabetes upregulation [DOI] 10.1016/j.mehy.2020.110247 PMC 바로가기 [Article Type] Article
Combined use of murine double minute-2 promoter methylation and serum AFP improves diagnostic efficiency in hepatitis B virus-related hepatocellular carcinomaResearch Paper Published on 2020-10-232023-06-03 Journal: International Journal of Medical Sciences [Category] B형 간염, [키워드] DNA methylation HBV-related HCC MDM2 [DOI] 10.7150/ijms.47003 PMC 바로가기 [Article Type] Research Paper
Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genesResearch Published on 2020-10-142023-08-30 Journal: Genome Medicine [Category] E형 간염, [키워드] Autism Spectrum Disorder DNA methylation epigenetics epigenome Epigenome-wide association study neurodevelopment Prospective Study umbilical cord blood Whole-genome bisulfite sequencing X chromosome [DOI] 10.1186/s13073-020-00785-8 PMC 바로가기 [Article Type] Research
Genopo : a nanopore sequencing analysis toolkit for portable Android devicesArticle Published on 2020-09-292022-10-31 Journal: Communications Biology [Category] COVID-19, SARS, [키워드] Analysis bioinformatics can be used Community Complete computation computational analysis Computational platforms and environments coronavirus SARS-CoV-2 determine DNA and RNA DNA methylation DNA sequencing flexible Genome genome sequence genomes Human genome less Nanopore nine patient isolate performed resource sequenced Sequencing Sequencing analysis sequencing data Tablet toolkit utility [DOI] 10.1038/s42003-020-01270-z PMC 바로가기 [Article Type] Article