Emergence of novel combinations of SARS-CoV-2 spike receptor binding domain variants in Senegal세네갈에서 SARS-CoV-2 스파이크 수용체 결합 도메인 변이체의 새로운 조합의 출현Article Published on 2021-12-082022-09-10 Journal: Scientific Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Combination coronavirus Course Diseases E484K emergence escape mutation Evidence evidence of Evolution genetics genomes Health care L452R Lineage lineages Local MONITOR Mutation mutations N501Y new SARS-CoV-2 next generation sequencing pandemic parallel evolution Receptor binding domain respiratory S477N SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike mutations second wave sequence sequenced Sequencing severe acute respiratory syndrome Coronavirus specimen specimens spike gene Treatment variant whole genome [DOI] 10.1038/s41598-021-02874-z PMC 바로가기 [Article Type] Article
Did Climate Change Influence the Emergence, Transmission, and Expression of the COVID-19 Pandemic?Medicine Published on 2021-12-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] activity affected affecting bat caused change Climate Climate change Community condition coronavirus COVID-19 COVID-19 pandemic emergence environmental factor Epidemics expression Factor Health homeostasis Host host immunity humans Infection influence Novel coronavirus outcome pandemic Pandemics problem reservoirs respiratory survived temperature Transmission vectors virus [DOI] 10.3389/fmed.2021.769208 PMC 바로가기 [Article Type] Medicine
Emergence of SARS-CoV-2 resistance mutations in a patient who received anti-SARS-COV2 spike protein monoclonal antibodies: a case report항 -SARS-COV2 스파이크 단백질 단일 클론 항체를받은 환자에서 SARS-COV-2 저항 돌연변이의 출현 : 사례 보고서Case Reports Published on 2021-12-072022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 변종, 진단, [키워드] B.1.1.7 B.1.1.7 variant Case report Combination coronavirus disease Coronavirus disease 2019 COVID-19 E484K emergence exposure to Immunosuppressed in vitro Infection K417N management measure monoclonal monoclonal antibodies monoclonal antibody Mutation offer Patient Protein raise receiving Resistance mutations selection respiratory SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutations selected Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Severe case spike Spike protein subsequent therapeutic Transmission variants virus [DOI] 10.1186/s12879-021-06902-1 PMC 바로가기 [Article Type] Case Reports
A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbations유전 및 약물 교란을 탐색하기 위한 3D 구조 SARS-CoV-2-인간 상호작용체Article Published on 2021-12-012022-09-11 Journal: Nature methods [Category] SARS, 변종, 신약개발, 유전자 메커니즘, [키워드] binding affinity candidate carried changes in COVID-19 pandemic downstream driven by emergence enrichment etiology Evolution facilitate followed by Genetic Host human population hypothese Interaction interface Meta-analysis molecular docking new viral agent new viral agents performed Perturbation predict predicted receptor ACE2 resource SARS-CoV-1 SARS-CoV-2 sequence Spike protein targets the spike protein Transmission variant Viral protein Viral proteins virulence [DOI] 10.1038/s41592-021-01318-w PMC 바로가기 [Article Type] Article
The Emergence of Cryptococcemia in COVID-19 Infection: A Case ReportInternal Medicine Published on 2021-11-202022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress association Blood C. neoformans Case report Central nervous system clearance clinical suspicion clinically coronavirus coronavirus disease COVID-19 COVID-19 patient Cryptococcemia Cryptococcus neoforman cryptococcus neoformans (c. neoformans) Culture demonstrated detrimental Dexamethasone Diabetes Mellitus diagnosed emergence fungal fungemia Hispanic Host hypertension immunocompetent Immunocompromised patient Infection infections intravenous maintaining meningeal irritation Mortality Neurological deficit obesity opportunistic infection pandemic past medical history Patient Prevent Repeat report syndrome Topic treated treating COVID-19 patient [DOI] 10.7759/cureus.19761 PMC 바로가기 [Article Type] Internal Medicine
Postvaccination SARS-COV-2 among Health Care Workers in New Jersey: A Genomic Epidemiological Study뉴저지 주 의료 종사자의 백신 접종 후 SARS-COV-2: 게놈 역학 연구Research Article Published on 2021-11-172022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Administered Alter Analysis appear BNT162b2 BNT162b2 mRNA vaccine breakthrough Care Community COVID-19 COVID-19 cases COVID-19 pandemic Critical detect domain doses E484K effective vaccine Efficacy emergence epidemiological Epidemiology Evidence evidence of Frame Frequency genomic group groups hcp Health Health care Hospitalization immune evasion increase in indicated individual initial mRNA vaccine mRNA-1273 N-terminal domain N501Y New NTD oxygen Patient phylogenies polymorphism Polymorphisms populations positive postvaccination Prevalence probe professional provided question random Receptor-binding domain recipient recipients required robust SARS-CoV-2 SARS-CoV-2 mutant SARS-CoV-2 mutants Spike protein supplemental oxygen Support Surveillance tested Time frame Transmission transmission potential vaccinated groups vaccinated individuals vaccination Vaccine vaccine dose variants of concern Viral VoC VOCs WGS whole-genome sequencing worker [DOI] 10.1128/Spectrum.01882-21 PMC 바로가기 [Article Type] Research Article
Emergence of B.1.524(G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave제 3의 COVID-19 전염병 파에서 말레이시아에서 B.1.524 (G) SARS-COV-2의 출현Article Published on 2021-11-112022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] A701V Analysis carried Cluster contributing to COVID-19 COVID-19 case COVID-19 epidemic COVID-19 pandemic descendant East emergence epidemic wave epidemic waves epidemiological link Epidemiology Genetic variation Genetic variations Genome Genome sequencing independent Lineage lineages Malaysia Mutation mutations occurred Peninsular Malaysia performed Phylogenetic Protein remained Result S-D614G mutation SARS-CoV-2 SARS-CoV-2 strain Selangor sequence sequenced specific mutation specific mutations spike Spike protein Spread spread to Strains suggested Support the SARS-CoV-2 variant virus [DOI] 10.1038/s41598-021-01223-4 PMC 바로가기 [Article Type] Article
Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 Virus Variant With Novel Genomic Architecture in Hong Kong홍콩에서 새로운 게놈 구조를 가진 중증 급성 호흡기 증후군 코로나바이러스 2 바이러스 변종 출현Article Published on 2021-11-022022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 architecture C-terminally characterized coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 duplication emergence genomic genomic rearrangement Hong Kong Lineage lineages novel ORF6 ORF7a ORF7b ORF8 pandemic respiratory resulting SARS-CoV-2 SARS-CoV-2 variant substitutions Transposition UTR whole-genome sequencing [DOI] 10.1093/cid/ciab198 PMC 바로가기 [Article Type] Article
Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2SARS-CoV-2의 관심 대상인 새로운 B.1.621 변이체의 특성화Article Published on 2021-11-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] accumulation acute respiratory syndrome acute respiratory syndrome coronavirus affecting Amino acid amino acid change amino acid changes B.1.621 binding characterization circulating coronavirus E484K emergence escape Evolution fixation Frequency genetic diversity Genome sequencing herd immunity identify Immunity insertion Lineage N-terminal domain N501Y Nanopore natural infection Neutralizing antibodies P681H processed Protein protocol rapid increase RBD Receptor binding domain required S1/S2 cleavage site SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Substitution the Spike variant Variant of interest (VOI). virus transmissibility [DOI] 10.1016/j.meegid.2021.105038 PMC 바로가기 [Article Type] Article
Battle against the pandemic: Emergence of SARS-CoV2 variants and global challenge전염병과의 전쟁: SARS-CoV2 변종의 출현과 세계적인 도전Article Published on 2021-11-012022-09-11 Journal: Travel medicine and infectious disease [Category] SARS, 변종, [키워드] battle emergence SARS-CoV2 variant [DOI] 10.1016/j.tmaid.2021.102173 PMC 바로가기 [Article Type] Article