D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with RemdesivirD,L-리신-아세틸살리실레이트 + 글리신(LASAG)은 SARS-CoV-2 복제를 감소시키고 렘데시비르와 함께 추가 효과를 나타냅니다Article Published on 2022-06-212022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] Acetylsalicylic acid acting acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Additive additive effect adverse effect adverse effects Antiviral approach approved Aspirin cell culture system chip model Coagulation factors Combination complex coronavirus coronavirus disease Coronavirus disease-19 COVID-19 Cytokines disease Effect Efficacy expression glycine Healthcare system Healthcare systems in vitro inhibitory effect investigated L-lysine LASAG medication medications other diseases Patient pro-inflammation pro-inflammatory cytokine pro-inflammatory cytokines Remdesivir repurposing salt SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus show Therapeutic strategies therapeutic strategy these compound these compounds Vaccine viral infection while [DOI] 10.3390/ijms23136880 PMC 바로가기 [Article Type] Article
The Network of Services for COVID-19 Vaccination in Persons With Mental Disorders: The Italian Social Health System, Its Organization, and Bioethical IssuesReview Published on 2022-06-202023-07-09 Journal: Frontiers in Public Health [Category] COVID19(2023년), [키워드] COVID-19 vaccination Ethics Good practices Health services Healthcare system Mental Disorders Vaccine hesitancy [DOI] 10.3389/fpubh.2022.870386 PMC 바로가기 [Article Type] Review
Investigation of target sequencing of SARS-CoV-2 and immunogenic GWAS profiling in host cells of COVID-19 in Vietnam베트남 코로나19 숙주 세포에서 SARS-CoV-2 표적 염기서열 분석 및 면역원성 GWAS 프로파일링Article Published on 2022-06-192022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] affected AUC Biomarker clade clinical outcomes comprehensive analysis coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity COVID-19 treatment dataset delta variant Disease progression downstream analysis Elastic forest framework global pandemic GWAS Health Healthcare system Healthcare systems high accuracy Hospitalization host cell host cells immune response immune responses immunogenic Impact investigated investigation Predictive Predictive model prevalent Previous studies previous study progression Protein provided PRS Random forest Research risk risk score SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence Sequencing severity severity of COVID-19 SNP SVM the disease therapeutic target therapeutic targets Treatment Vietnam virus virus variant virus variants [DOI] 10.1186/s12879-022-07415-1 PMC 바로가기 [Article Type] Article
COVIDHunter: COVID-19 Pandemic Wave Prediction and Mitigation via Seasonality Aware ModelingCOVIDHunter: 계절성 인식 모델링을 통한 COVID-19 팬데믹 웨이브 예측 및 완화Article Published on 2022-06-172022-09-11 Journal: Frontiers in Public Health [Category] 변종, [키워드] applied average case study caused Climate condition country COVID-19 COVID-19 outbreak COVID-19 outbreak simulation COVID-19 patient COVID-19 test death deaths disease spread Early detection effective environmental condition epidemiological epidemiological modeling estimate evaluate Factors flexible geographical region Healthcare system hospitalizations Humidity implementation Infection Isolation measure Measures Mitigation modeling modify MONITOR outbreak outbreak prevention and control performed predict prediction Prevention and control provide seasonal epidemic seasonality source code Spread spread of COVID-19 strength Switzerland temperature the disease vaccination vaccination rate variants of concern Wave [DOI] 10.3389/fpubh.2022.877621 PMC 바로가기 [Article Type] Article
International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality Research Published on 2022-06-132022-10-05 Journal: NPJ Digital Medicine [Category] 유전자 메커니즘, [키워드] Admission age albumin Algorithm approach AST baseline Cohort Combination Comorbidity comparison country covariate COVID-19 hospitalization COVID-19 mortality Cox model Cox regression model CRP demographics died Europe evaluated feature Generalizability Healthcare system Healthcare systems highlighting hospitalized patient Laboratory male Model Mortality nine patients hospitalized predict predicted Predictive White blood cell with COVID-19 [DOI] 10.1038/s41746-022-00601-0 [Article Type] Research
A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort studyResearch article Published on 2022-06-092022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, 임상, [키워드] accelerate Accuracy agency APACHE II assessment Berlin Biomarker Biomarkers Charité clinical clinical disease progression Clinical outcome clinical risk clinical trials Cohort conducted Council COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 severity death Dexamethasone disease prognosis disease severity education ERC European finding foundation funding Germany hallmark Healthcare system healthy individuals help hospitalised introduced LC-MS/MS LLOQ machine learning median Medicine Mild Mobility moderate multiplex node observational study outcome Patient patient cohort patients with COVID-19 peptide peptides predicted Prognosis Prognostic value Protein proteomics quantification Registered registry Research resource SARS-CoV2 Science sensitivity severe COVID-19 severity Severity stratification SOFA Spectrometry Standard of care stratified Support supported survival System targeted proteomics the median the WHO Therapies Treatment Wellcome Trust [DOI] 10.1016/j.eclinm.2022.101495 [Article Type] Research article
Clinical outcomes associated with SARS-CoV-2 Omicron (B.1.1.529) variant and BA.1/BA.1.1 or BA.2 subvariant infection in Southern California Research Published on 2022-06-082022-10-05 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] acute respiratory syndrome Admission B.1.1.529 B.1.617.2 change clinical Clinical outcome coronavirus COVID-19 death Delta delta variant dominant explained hazard ratio healthcare Healthcare system Hospital admission Hospitalization immune protection individual Infection infections intensive care Lower mechanical ventilation occurred omicron outcome progression public health reduced reduced risk risk SARS-CoV-2 SARS-CoV-2 lineage severity Surveillance symptomatic vaccinated against COVID-19 variant [DOI] 10.1038/s41591-022-01887-z [Article Type] Research
Perspectives on Subcutaneous Infliximab for Rheumatic Diseases and Inflammatory Bowel Disease: Before, During, and After the COVID-19 Era류마티스 질환 및 염증성 장 질환에 대한 피하 인플릭시맙의 전망: COVID-19 시대 전, 중, 후Review Published on 2022-06-012022-09-12 Journal: Advances in therapy [Category] MERS, 진단, [키워드] administration anticipated approval benefit Biobetters bowel clinical advantage clinical benefit clinical trial coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 CT-P13 SC Drug administration Efficacy and safety gastroenterology Guidance hcp healthcare Healthcare professional Healthcare system Healthcare systems IBD implementation improvement Inflammatory bowel disease infliximab Innovative biologics intravenous IV infusion management Nosocomial infection offer pandemic Patient Patient care Patient satisfaction patients Physicians Potential preference provide real-world data Real-world evidence reduced reduction in Regulatory resource rheumatic disease Rheumatic diseases rheumatoid arthritis rheumatology risk selected significant changes in Subcutaneous Subcutaneous infliximab suggested Support supported switching Telemedicine therapy Treatment [DOI] 10.1007/s12325-021-01990-6 PMC 바로가기 [Article Type] Review
Incessant threat of COVID-19 variants: Highlighting need for a mix of FDA-approved artificial intelligence tools and community pharmacy servicesCOVID-19 변종에 대한 끊임없는 위협: FDA 승인 인공 지능 도구와 지역사회 약국 서비스의 혼합 필요성 강조Article Published on 2022-06-012022-09-11 Journal: Research in social & administrative pharmacy : RSA [Category] COVID19(2023년), SARS, 변종, [키워드] artificial intelligence build Care Community Compliance COVID-19 effective Guidance Healthcare system hospital increasingly Pathways Pharmacy preventive measure the WHO [DOI] 10.1016/j.sapharm.2021.07.018 PMC 바로가기 [Article Type] Article
Pediatric emergency care in New York City during the COVID-19 pandemic shutdown and reopening periodsCOVID-19 전염병 폐쇄 및 재개 기간 동안 뉴욕시의 소아 응급 치료Article Published on 2022-06-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 변종, [키워드] affected Asthma Care Characteristics children city Community coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 pandemic cross-sectional analysis Decline declined decrease demographics diagnose Diagnosis disposition Emergency emergency department evaluated events finding Health Healthcare system increase in infections information initial Injury lockdown medical illness New York New York City pandemic Patient peaked pediatric Penetrating presenting Public public health Public Hospital relative Relative risk reported resource risk significantly higher significantly increased state of emergency the United State this system understanding United States variant Volume [DOI] 10.1016/j.ajem.2022.03.049 PMC 바로가기 [Article Type] Article