Profile of Immunoglobulin G N -Glycome in COVID-19 Patients: A Case-Control StudyCOVID-19 환자의 면역글로불린 G N-Glycome 프로필: 사례-대조군 연구Immunology Published on 2021-09-232022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] Activation ADCC age analyzed approach case-control study cell cytotoxicity changes in clinical phenotype Complement pathway complex conducted contribute Coronavirus disease 2019 COVID-19 COVID-19 pathogenesis COVID-19 patient decrease glycosylation Health healthy controls healthy individual hydrophilic IgG immune responses Immunoglobulin G Inflammatory cytokines Interaction N -glycosylation previous study profile recruited SARS-CoV-2 SARS-COV-2 infection severe cases severity of COVID-19 suggested upregulate [DOI] 10.3389/fimmu.2021.748566 PMC 바로가기 [Article Type] Immunology
Do you have COVID-19? An artificial intelligence-based screening tool for COVID-19 using acoustic parameters a)Special Issue on Covid-19 Pandemic Acoustic Effects Published on 2021-09-162022-10-31 Journal: The Journal of the Acoustical Society of America [Category] COVID-19, SARS, [키워드] abnormality Accuracy breath category Confusion COVID-19 COVID-19 patient develop fundamental frequency Health healthy individual Logistic regression parameter Precision produced recall Respiratory system selected sustained tested was used [DOI] 10.1121/10.0006104 PMC 바로가기 [Article Type] Special Issue on Covid-19 Pandemic Acoustic Effects
High estradiol and low testosterone levels are associated with critical illness in male but not in female COVID-19 patients: a retrospective cohort study높은 에스트라디올과 낮은 테스토스테론 수치는 남성의 심각한 질병과 관련이 있지만 여성의 COVID-19 환자와는 관련이 없습니다: 후향적 코호트 연구Original Article Published on 2021-09-142022-09-10 Journal: Emerging Microbes & Infections [Category] Coronavirus, SARS, 치료기술, [키워드] Admission analysed chemokine chemokines cohorts Comorbidity COVID-19 COVID-19 cohort COVID-19 patient COVID-19 patients Critical Critical illness Critically ill cytokine Cytokines death disease severity ECMO elevated estradiol estradiol level female hallmark healthy individual healthy individuals Heart diseases ICU IFN-γ intensive care intensive care unit Linear regression analysis male metabolism non-COVID-19 patient Non-COVID-19 patients prevalent receive reduced regression analysis retrospective cohort study risk factor SARS-CoV-2 Sex sex differences sex hormone Sex hormones significantly statistically significant difference Testosterone Treatment [DOI] 10.1080/22221751.2021.1969869 PMC 바로가기 [Article Type] Original Article
Characterization by Quantitative Serum Proteomics of Immune-Related Prognostic Biomarkers for COVID-19 SymptomatologyCOVID-19 증상에 대한 면역 관련 예후 바이오마커의 정량적 혈청 단백질체학에 의한 특성화Immunology Published on 2021-09-082022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] affecting Algorithm Analysis Asymptomatic biological processe Biomarker Biomarkers caused characterization Cohort contribute contributed correlated COVID-19 COVID-19 disease COVID-19 pandemic Data analysis diagnostic disease Disease progression disease progression and severity disease symptom disease symptoms disorder disorders dysregulated ELISA Factor FIVE healthy healthy individual healthy individuals hospital discharge Hospitalized immunology increase intensive care intensive care unit molecular interaction pandemic physiological PON1 Predictive Predictive value profile prognostic prognostic biomarker Prognostic biomarkers Protein proteomic proteomics Quantitative representation SARS-CoV-2 selected SELENOP Selenoprotein P Serum protein serum proteins severe cases severity significantly Symptomatology systemic inflammation therapeutic intervention translational with COVID-19 zone [DOI] 10.3389/fimmu.2021.730710 PMC 바로가기 [Article Type] Immunology
The Vitamin D, IL-6 and the eGFR Markers a Possible Way to Elucidate the Lung–Heart–Kidney Cross-Talk in COVID-19 Disease: A Foregone ConclusionArticle Published on 2021-09-072022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] accompanied baseline city clinician Concentration conducted control group Coronavirus 19 (COVID-19) COVID-19 COVID-19 affected patient COVID-19 disease COVID-19 patient Department develop disease disorder EGFR Emergency exhibited facilitated glomerular glomerular filtration rate healthy individual heart failure help IL-6 Immune-mediated impairment in both groups include increased mortality Italy kidney lung lung disorder lung–heart–kidney cross-talk majority Non-COVID-19 non-COVID-19 patient Older age older patient participant pathology pathway Patient patients with COVID-19 preexisting comorbidity progression Proinflammatory cytokine recent findings reduced renal researcher response risk risk factor SARS-CoV-2 serum study group Therapeutic approach three groups Trial Vitamin D worsening [DOI] 10.3390/microorganisms9091903 PMC 바로가기 [Article Type] Article
Influence of Health Beliefs on COVID-19 Vaccination among Individuals with Cancer and Other Comorbidities in Puerto RicoArticle Published on 2021-09-062022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adults Analysis belief Cancer cancer diagnosis chronic condition Comorbidities Comorbidity COVID-19 COVID-19 susceptibility COVID-19 vaccination diagnosed diagnosis of cancer disease status female Health Health Belief Model healthy healthy individual higher odd highlight individual Infection influence information Model Older Other outcome participant Participants Population populations Puerto Rico severity significantly higher Study participants susceptible used data vaccination Vaccine was used with COVID-19 [DOI] 10.3390/vaccines9090994 PMC 바로가기 [Article Type] Article
Torquetenovirus in saliva: A potential biomarker for SARS-CoV-2 infection?타액의 Torquetenovirus : SARS-COV-2 감염을위한 잠재적 인 바이오 마커?Research Article Published on 2021-08-242022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 바이오마커, [키워드] age amplification analyzed biological fluid biological fluids Biomarker both groups chronic infection chronic infections correlated COVID-19 diarrhea fatigue Fever Gender gene amplification group healthy individual healthy individuals Immune status individual likelihood Loss Loss of Smell marker mild respiratory symptoms nasopharynx negative controls positive positive individuals predict prevalent Prognosis provided remained resolved respiratory respiratory symptoms Saliva saliva samples SARS-CoV-2 SARS-CoV-2-positive individual SARS-CoV-2-positive individuals sore throat subject Symptom symptom duration symptom resolution the SARS-CoV-2 titer titers transplants was collected were assessed [DOI] 10.1371/journal.pone.0256357 PMC 바로가기 [Article Type] Research Article
Elevated Neopterin Levels Predict Fatal Outcome in SARS-CoV-2-Infected PatientsCellular and Infection Microbiology Published on 2021-08-232022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, [키워드] Biomarker Blood Blood level Care caused characterized Clinical outcome Comorbidities Comorbidity Concentration Coronavirus disease 2019 coronavirus epidemics Critically ill death deaths detrimental disease disease severity elevated ELISA Evolution Factor hallmark healthy donor healthy individual high-risk population hospital Hospital admission Host identify immune activation Infection Innate Innate immunity Level Neopterin non-survivor Patient quantified Result SARS-CoV SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 viral infection sensitivity serum specificity stratified survivor symptomatic systemic viral infection [DOI] 10.3389/fcimb.2021.709893 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Longitudinal analysis to characterize classes and subclasses of antibody responses to recombinant receptor-binding protein (RBD) of SARS-CoV-2 in COVID-19 patients in Thailand태국의 COVID-19 환자에서 SARS-COV-2의 재조합 수용체-결합 단백질 (RBD)에 대한 항체 반응의 클래스 및 서브 클래스를 특성화하기위한 종단 분석Research Article Published on 2021-08-102022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin Angiotensin-converting enzyme antibody Antibody assays Antibody Response Antibody responses contribute convalescent sera convalescent serum coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient COVID-19 patients Dengue fever detect domain ELISA ELISAs febrile healthy individual healthy individuals highest Host Human human immune response IgA IgG IgG level IgG levels IgG subclasse IgG subclasses IgG1 IgG3 IgM immune responses Infection Influenza Interpretation investigated leptospirosis longitudinal median molecular assays murine murine typhus natural infection ORF1ab ORF1ab gene outbreak Patient patients patients with COVID-19 Protein RBD RBD antigen reactivity respiratory RT-PCR SARS-CoV-2 SARS-COV-2 infection sera serological assays serum serum sample serum samples severe acute respiratory syndrome Coronavirus significantly higher Spike protein target tested Therapeutics tropical typhus Viral Viral detection viral spike protein [DOI] 10.1371/journal.pone.0255796 PMC 바로가기 [Article Type] Research Article
SCAPTURE: a deep learning-embedded pipeline that captures polyadenylation information from 3′ tag-based RNA-seq of single cellsMethod Published on 2021-08-102022-11-01 Journal: Genome Biology [Category] COVID-19, MERS, SARS, [키워드] Accuracy Analysis APA Cell change cleavage de novo deep learning detect develop evaluate Gene Expression healthy individual identify identity information PAS PBMC Peak calling polyadenylation site profile RNA-Seq scRNA-seq scRNA-seq data sensitivity Single Cell single-cell supplementary material transcript Transcript quantification [DOI] 10.1186/s13059-021-02437-5 PMC 바로가기 [Article Type] Method