iCAT: diagnostic assessment tool of immunological history using high-throughput T-cell receptor sequencingiCAT: 고처리량 T 세포 수용체 시퀀싱을 사용한 면역학적 병력의 진단 평가 도구Software Tool Article Published on 2021-06-292022-09-12 Journal: F1000Research [Category] MERS, 진단, [키워드] absence Accuracy Biomarker Biomarkers can be used Classifier Cohort COVID-19 diagnose diagnosed diagnostic diagnostic classification DNA sequence Genetic high accuracy identify immune immunological independent Infection mice naïve pathogen pathogen-specific positive provide R software package R-package recorded SARS-CoV-2 sequence Sequencing statistically T-cell T-cell receptor T-cell receptor sequencing T-cell Response TCR loci TCR sequence TCR sequencing TCRs unique virus [DOI] 10.12688/f1000research.27214.2 PMC 바로가기 [Article Type] Software Tool Article
Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization멘델식 무작위 배정에 적용한 중국 코호트에서 ABO 혈액형의 게놈 연관성 대 혈청학적 결정Article Published on 2021-06-242022-09-10 Journal: Genes [Category] MERS, 변종, 유전자 메커니즘, [키워드] ABO ABO blood types ABO gene ABO type Analysis application biochemically Blood blood pressure Chinese Chinese cohort Cohort conducted Determination determined by evaluated Genetic polymorphism genetic polymorphisms Genetic variant Genome-wide association study genotyping Han Chinese high accuracy human population human populations instrumental variables macro mapped mechanism mendelian randomization nucleotide Predictive Respiratory failure rs8176719 severe COVID-19 Significant Single nucleotide polymorphism single nucleotide polymorphisms Type [DOI] 10.3390/genes12070959 PMC 바로가기 [Article Type] Article
A new grey quadratic polynomial model and its application in the COVID-19 in ChinaArticle Published on 2021-06-152022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] China confirmed cases COVID-19 death case develop Diseases early stage Engineering expression high accuracy mathematical observation Precision restored [DOI] 10.1038/s41598-021-91970-1 PMC 바로가기 [Article Type] Article
Predicting the incidence of COVID-19 using data miningResearch Article Published on 2021-06-072022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] Algorithm analyzed classification confirmed case country COVID-19 COVID-19 case Data mining dataset geographical region Health help high accuracy incidence incidence of COVID-19 incidence rate information Johns Hopkins University less mean absolute error pandemic predict predicted Predicting Prevalence prevalence of COVID-19 professional provided question Region Result supplementary material the disease three group variables [DOI] 10.1186/s12889-021-11058-3 PMC 바로가기 [Article Type] Research Article
Nucleic Acid Testing of SARS-CoV-2SARS-CoV-2의 핵산 테스트Review Published on 2021-06-072022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Accuracy acid amplification caused Chain Reaction coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis CRISPR develop Diagnostic method diagnostic methods diagnostics digital PCR focus Genome sequencing high accuracy highlight isothermal amplification Loop-mediated isothermal amplification Metrology molecular Nanotechnology Next-generation sequencing NGS nucleic acid Nucleic acid detection nucleic acid testing outbreak PCR polymerase polymerase chain polymerase chain reaction powerful tool Reference materials resource reverse transcription Reverse transcription-polymerase chain reaction RT-LAMP RT-PCR RT-RPA SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 nucleic acid testing SARS-CoV-2 RNA sensitivity Standardization Testing virus [DOI] 10.3390/ijms22116150 PMC 바로가기 [Article Type] Review
COVID-19 Diagnosis Using an Enhanced Inception-ResNetV2 Deep Learning Model in CXR ImagesCXR 이미지에서 향상된 Inception-ResNetV2 딥 러닝 모델을 사용한 COVID-19 진단Research Article Published on 2021-06-032022-09-10 Journal: Journal of Healthcare Engineering [Category] MERS, SARS, 진단, 치료기술, [키워드] accelerate Accuracy Algorithm Chain Reaction chest X-ray connection Convolutional neural networks COVID-19 COVID-19 infection COVID-19 pandemic CXR deep deep learning detect diagnose Diagnosis ENhance enhanced Health high accuracy Image inception introduced lack learning lung Lungs Model PCR polymerase chain reaction Precision recall Region researcher time-consuming Visualization [DOI] 10.1155/2021/6658058 PMC 바로가기 [Article Type] Research Article
Side Effects and Perceptions Following COVID-19 Vaccination in Jordan: A Randomized, Cross-Sectional Study Implementing Machine Learning for Predicting Severity of Side EffectsArticle Published on 2021-05-262022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] analyzed AstraZeneca blood clot chills Cohen’s kappa conducted coronavirus disease COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cross-sectional demographic data Dizziness Effect Efficacy and safety fatigue Fever headache high accuracy Hospitalization immune system Implementing indicated involved joint Jordan machine learning Mild moderate MOST myalgia Pain pandemic participant Perception Pfizer-BioNTech post-vaccination symptoms predict predicted protocol random receiving Safe SARS-CoV-2 vaccine Severe case severity side Side effect Side effects Sinopharm statistical analysis statistically suffered thrombocytopenia thrombosis vaccination Vaccine Vaccine acceptance vaccine anxiety Vaccine hesitancy Vaccines Variation were used [DOI] 10.3390/vaccines9060556 PMC 바로가기 [Article Type] Article
Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release AssaySARS-CoV-2 감염 후 구조 단백질의 광범위한 T 세포 표적화: 자동화된 인터페론 감마 방출 분석을 사용한 T 세포 반응성의 높은 처리량 평가Immunology Published on 2021-05-202022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료법, [키워드] Antibody titer Antigen antigens approach assessment automated body mass body mass index breadth C-terminus characteristic comparable confirmed case confirmed cases Control control subjects convalescent coronavirus disease Coronavirus disease 2019 correlated COVID-19 days post infection Elecsy Elecsys facilitate followed by fresh whole blood Gamma groups high accuracy high through put IgG immune response immune responses Infection interferon gamma interferon gamma release assay (IGRA) large cohort less magnitude membrane nucleocapsid PCR positive Protein reactivity Release Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SCT seropositive seropositive individual Seropositivity Sex significantly specific antibodies structural protein structural proteins subject T cell T cell response T cell responses T cells targeting targets tested throughput virion virus was performed were assessed Whole blood [DOI] 10.3389/fimmu.2021.688436 PMC 바로가기 [Article Type] Immunology
A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failureArticle Published on 2021-05-182022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] abnormality accumulating Acute respiratory failure Admission alteration Analysis ANOVA applied ARF association bile acids Bioavailability Biochemistry Biomarkers biosynthetic change characterized cofactor Critically ill patient detect determine disorders dysfunction Efficiency Evidence FDR high accuracy hospital discharge include intensive care mechanical ventilation Medical research metabolism metabolite metabolome metabolomic mitochondrial morbidity and mortality Mortality NADP nicotinamide adenine dinucleotide non-survivor outcome pathway Patient phosphate predict predicted Prevalence Quantitative reduce mortality Respiratory failure Riboflavin semi-quantitative Sepsis serum severity Significant substrate survival survivor Survivors Systems biology target Treatment [DOI] 10.1038/s41598-021-89716-0 PMC 바로가기 [Article Type] Article
Transfer Learning to Detect COVID-19 Automatically from X-Ray Images Using Convolutional Neural NetworksResearch Article Published on 2021-05-152022-10-29 Journal: International Journal of Biomedical Imaging [Category] COVID-19, [키워드] Accuracy Algorithm Algorithms biological marker caused chest X-ray CNNs contagious COVID-19 COVID-19 diagnosis COVID-19 infection Critical CXR dataset death deep learning diagnosis of COVID-19 disease Effectiveness experiment Healthcare professional healthy individuals help high accuracy highest identify Image IMPROVE individual individuals with COVID-19 infections learning network Neural novel coronavirus disease offer pandemic Precision preventive measure required resources sensitivity significantly specificity the disease transfer Viral pneumonia with COVID-19 X-ray [DOI] 10.1155/2021/8828404 PMC 바로가기 [Article Type] Research Article