COVID-19 as the cause of thrombosis: recognising COVID-19 infection in apparently asymptomatic patients혈전증의 원인인 코로나19: 무증상 환자에서도 코로나19 감염 인지Case Reports Published on 2021-01-072022-09-11 Journal: BMJ case reports [Category] 치료기술, [키워드] abdominal pain asymptomatic patient Case report clinician COVID-19 COVID-19 infection Critically ill critically ill patients CT scan develop disease emergency department emergency medicine Evidence evidence of Factor hypercoagulable manifestation mild respiratory no risk Pain Patient PCR test presenting presenting symptom pulmonary renal respiratory Respiratory failure respiratory symptom respiratory symptoms Risk factors secondary to subsequent Symptom the patient thrombosis thrombotic thrombotic complication Thrombotic complications thrombotic event Thrombus treat [DOI] 10.1136/bcr-2020-241027 PMC 바로가기 [Article Type] Case Reports
Placental Pathology in COVID-19: Case Series in a Community Hospital SettingObstetrics/Gynecology Published on 2021-01-062022-10-31 Journal: Cureus [Category] COVID-19, [키워드] activity Admission appearance Barnaba Blood Group center Coagulation Cohort control group coronavirus Coronavirus disease-19 COVID COVID-19 COVID-19 infection COVID-19 test death Department dysregulation eight Evidence examined feature fetal fibrin thrombi greater Grimace hypercoagulable incidence individual Infectious disease Inflammation Injury malperfusion maternal medicine microcalcifications microscopic features Monmouth MOST mother Nasopharyngeal swab Neonate objective obstetrics other variables outcome Patient perinatal pathology Placenta placental pathology positive positive COVID-19 pregnant women Prevalence Respiration Result Retrospective study Robert Sery setting surgical specimen tested virus with COVID-19 women wood [DOI] 10.7759/cureus.12522 PMC 바로가기 [Article Type] Obstetrics/Gynecology
SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotypeSARS-CoV-2 감염은 전혈전성 혈소판 표현형과 관련이 있습니다Article Published on 2021-01-052022-09-11 Journal: Cell Death & Disease [Category] 치료기술, [키워드] abnormal coagulation Activation addition Adhesion Molecule adhesion molecules antibodies antiplatelet Antithrombotic cardiovascular complications CD63 characterized Coagulation complex condition contribute Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients COVID-19 sample COVID-19 samples Cytometry donors expressed expression healthy control healthy controls hospitalized COVID-19 patient hospitalized COVID-19 patients hypercoagulable Hypercoagulable state in vitro incidence intensity intensive care intensive care support interactions investigated involved LAMP marker mass Mechanisms of disease median novel Novel coronavirus novel coronavirus disease P-selectin parameter patients peptide phenotype phenotypical Platelet platelet activation Platelets pro-thrombotic reduced Research SARS-COV-2 infection selectin signal intensity significantly Stimulation Support thrombin thrombin receptor transmembrane protein TRAP Treatment viral infection [DOI] 10.1038/s41419-020-03333-9 PMC 바로가기 [Article Type] Article
Case Report: Ischemic Colitis in Severe COVID-19 Pneumonia: An Unforeseen Gastrointestinal Complication증례 보고서: 중증 COVID-19 폐렴의 허혈성 대장염: 예상치 못한 위장 합병증Case Reports Published on 2021-01-032022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, 변종, [키워드] angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 cause clinical manifestation clinical manifestations Coagulopathy Colitis colonic Complication contributing to COVID-19 COVID-19 pneumonia Gastrointestinal GI Tract hemodynamic hypercoagulable Hypercoagulable state intestinal enterocytes involved Ischemia Ischemic Ischemic colitis key factor manifestation Manifestations multifactorial occlusive Pathogenesis pathogenesis of COVID-19 Pathologies pathology Pneumonia receptor receptors SARS-CoV-2 Severe COVID-19 pneumonia severely ill patient severely ill patients thromboembolic thromboembolic complications variant Vasopressor vasopressors [DOI] 10.4269/ajtmh.20-1262 PMC 바로가기 [Article Type] Case Reports
Platelets and renal failure in the SARS-CoV-2 syndromeSARS-CoV-2 증후군의 혈소판 및 신부전Article Published on 2021-01-022022-09-12 Journal: Platelets [Category] SARS, 진단, [키워드] ACE ACE2 ACE2 receptor ACE2 receptors activated Acute kidney injury acute respiratory syndrome AKI C reactive protein caused cleavage Cohort coronavirus coronavirus disease correlation COVID-19 COVID-19 disease COVID19 patients Critically ill CRP D-dimer D-dimer level disease elevated etiology facilitate feature ferritin GFR glomerular filtration rate granular Host human cells hypercoagulability hypercoagulable incidence Interaction lactate dehydrogenase LDH mean platelet volume modulation MPV negative correlation patients Platelet protease receptor renal renal failure Respiratory failure SARS-CoV-2 syndrome the SARS-CoV-2 unique viral infection viral spike protein Volume with COVID-19 [DOI] 10.1080/09537104.2020.1817361 PMC 바로가기 [Article Type] Article
Design and Rationale of a Randomized, Double-Blind, Placebo-Controlled, Phase 2/3 Study Evaluating Dociparstat in Acute Lung Injury Associated with Severe COVID-19Clinical Trial Published on 2021-01-012022-10-05 Journal: Advances in therapy [Category] SARS, 임상, [키워드] acute lung injury added advance anti-inflammatory properties approach Biomarker bleeding cause caused coagulation disorder Cohort contributed COVID-19 Critical care D-dimer determine Dexamethasone Dociparstat double-blind Efficacy Emergency use endpoints enrolled Evaluating Extracellular global pandemic HMGB1 hospital hospital ward Hospitalized hypercoagulable Hyperinflammatory Hypoxemia IL-6 Infection lung mechanical ventilation morbidity and mortality NETs Neutrophil extracellular traps New NIAID Novel coronavirus P-selectin participant pathology Patient patients patients with COVID-19 performed phase Phase 2 phase 2/3 trial Phase 3 Placebo placebo-controlled platelet factor 4 Platelet factor 4. positive primary endpoint proportion Randomized rationale reduced risk Respiratory failure robust SARS-CoV-2 sodium Standard of care subsequent supplemental oxygen treat with COVID-19 [DOI] 10.1007/s12325-020-01539-z PMC 바로가기 [Article Type] Clinical Trial
Interleukin-6 receptor blockade with subcutaneous tocilizumab improves coagulation activity in patients with COVID-19피하 토실리주맙을 사용한 인터루킨-6 수용체 차단은 COVID-19 환자의 응고 활성을 개선합니다Article Published on 2021-01-012022-09-12 Journal: European journal of internal medicine [Category] 진단, [키워드] 95% confidence interval 95%CI activate activated Admission age Analysis Anticoagulants blockade Blood coagulation C-reactive protein change Coagulation Coagulation parameters contribute COVID-19 COVID-19 pathogenesis COVID-19 patient Critical cytokine D-dimer level death develop dose enrolled evaluate the effect fibrinogen humanized monoclonal antibody hypercoagulable hyperinflammation Hyperinflammatory IMPROVE increase in Inflammation interleukin-6 interleukin-6 receptor interquartile range laboratory-confirmed moderate occurred Occurrence parameter Patient patients with COVID-19 Platelet Pneumonia Prophylactic Prophylaxis Prothrombin time receiving receptor reduction reduction in Respiratory function Standard of care Subcutaneous subcutaneous dose sustained therapeutic thromboembolic complications Thromboprophylaxis thrombosis Tocilizumab Treatment were measured [DOI] 10.1016/j.ejim.2020.10.020 PMC 바로가기 [Article Type] Article
Coagulopathy in patients with COVID-19: a systematic review and meta-analysisCOVID-19 환자의 응고병증: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2020-12-312022-09-10 Journal: Aging (Albany NY) [Category] SARS, 바이오마커, [키워드] 95% CI abnormality activated analyzed association CNKI Coagulation coagulation parameter Coagulation parameters Coagulopathy conducted coronavirus COVID-19 COVID-19 illness COVID-19 patient COVID-19 patients COVID-19 symptoms D-dimer disease severity exhibited exhibiting fibrinogen hypercoagulable investigated less medRxiv Meta-analysis not differ parameter partial thromboplastin times Patient performed Platelet prothrombin Prothrombin time severe symptom severe symptoms severity of COVID-19 SMD statistical analysis Symptom systematic literature search systematic review thrombotic Thrombotic events [DOI] 10.18632/aging.104138 PMC 바로가기 [Article Type] Meta-Analysis
Coagulopathy in elderly patients with coronavirus disease 2019Original Article Published on 2020-12-292022-10-28 Journal: Aging Medicine [Category] COVID-19, [키워드] age Aged analyzed blood coagulation disorders C‐reactive protein Characteristics clinical feature coagulation parameter Coagulopathy coronavirus disease COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 D‐dimer Elderly patient elevated fibrinogen group groups hospital hypercoagulable Inflammation Inflammatory marker investigated Older outbreak parameter Patient positive correlation proportion Prothrombin time reported Result SARS‐CoV‐2 infection significant difference significantly systemic inflammation [DOI] 10.1002/agm2.12133 PMC 바로가기 [Article Type] Original Article
COVID-19 Infection and Acute Pulmonary Embolism in an Adolescent Female With Sickle Cell DiseasePediatrics Published on 2020-12-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Adolescent Anemia Cell Chest chest pain cough COVID-19 COVID-19 infection diagnosed diagnosed with COVID-19 Diagnosis disease Embolism Escalation female healthy hypercoagulable increased risk Infection moderate MOST Patient pediatric Prophylaxis pulmonary Pulmonary embolism severe symptom Shortness of breath Sickle Sickle cell disease sickle cell hbsc syndrome Treatment Venous Thromboembolism VTE workup [DOI] 10.7759/cureus.12348 PMC 바로가기 [Article Type] Pediatrics