IL-2 – Page 9 – Communicable Diseases Research

COVID-19 and Cancer: Discovery of Difference in Clinical Immune Indexes

Research Article

Published on 2021-10-182022-10-29
Journal: Journal of Immunology Research [Category] COVID-19, MERS, SARS,

[키워드] Acute inflammation affected analyzed ANOVA B cell B cells Cancer Cancer patients cancers carried CD16 CD19 CD3 CD4 CD56 CD8 changes in characteristic chi-square test clinical correlation Correlation analysis COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines diagnostic difference Diseases Effect identify IFN IL-10 IL-2 IL-4 IL-6 Immune cell immune disorder involved Lymphocyte subset lymphopenia Monocytes Neutrophils NK cell no significant difference objective outcomes parameter Patient patients with COVID-19 Result Retrospective study ROC severe COVID-19 patient significant difference Stage subgroup analysis subset T cell T cells TNF- α two subgroups variable were measured with COVID-19
[DOI] 10.1155/2021/8669098 PMC 바로가기 [Article Type] Research Article

Prime-Boost Vaccination With Covaxin/BBV152 Induces Heightened Systemic Cytokine and Chemokine Responses

Immunology

Published on 2021-10-152022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, SARS,

Presentation of cytokine profile in relation to oxidative stress parameters in patients with severe COVID-19: a case-control pilot study

Research Article

Published on 2021-10-142022-10-31
Journal: F1000Research [Category] COVID-19, MERS, SARS,

Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure

임상 적으로 명백한 신장 질환이없는 COVID-19 환자에서 급성 및 만성 부전이없는 환자에서 면역 학적 활성화의 종 방향 비뇨기 바이오 마커

Article

Published on 2021-10-042022-08-31
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 유전자 메커니즘,

[키워드] Activation Acute kidney injury Admission affected APACHE Biomarker Blood CCL23 Chronic kidney disease clinical status clinically collected condition correlated COVID-19 Critical cross-sectional cross-sectional study CXCL6 DCN death demise dysfunction EGF ferritin followed by Gender Hospital admission IFNg IgM and IgG IL-12 IL-15 IL-18 IL-2 IL-5 IL-6 immune activation immune response immune system immunological immunology inflammatory markers kidney Kidney disease Kidney function Kidney injury LAG-3 longitudinal marker MCP-1 MCP-3 MMP7 modulate modulating Nephrology Non-survivors Patient patients PD-L1 PGF predicted Probability procalcitonin PTN Serum level Seven Spike protein Steroids trajectory unique urinary Urine Viral viral burden
[DOI] 10.1038/s41598-021-99102-5 PMC 바로가기 [Article Type] Article

Clinical Predictors of Mortality and Critical Illness in Patients with COVID-19 Pneumonia

Article

Published on 2021-10-022022-10-30
Journal: Metabolites [Category] COVID-19,

[키워드] Accuracy Admission age Analysis analyzed Aspirin AUC biochemical BUN center clinical clinician collected COVID-19 COVID-19 patients COVID-19 severity Critical disease CXCL-10 cytokine level Cytokine storm death Department develop Diabetes Mellitus diagnosed with COVID-19 diagnostic discharge disease severity early treatment Factor GCSF help hematological Hemodialysis HFNC high flow higher risk hypertension identify identifying IL-2 IL-6 illness immunological include increased mortality insulin resistance Intervention invasive ventilation Laboratory Lung disease main outcome measure male Mortality multivariate NLR non-survivor Oxygen therapy Patient patients patients with COVID-19 PPV Predictive predictors Radiographic reduce reduced regression analysis risk of death SARS-CoV-2 sensitivity significantly specificity study population suffered Symptom utility variable were used with COVID-19
[DOI] 10.3390/metabo11100679 PMC 바로가기 [Article Type] Article

Cerebrospinal fluid cytokine, chemokine, and SARS-CoV-2 antibody profiles in children with neuropsychiatric symptoms associated with COVID-19

Research article

Published on 2021-10-012022-10-05
Journal: Multiple sclerosis and related disorders [Category] SARS, 바이오마커,

[키워드] analyzed antibody Biomarker Case series cerebrospinal fluid chemokine chemokines children children with COVID-19 clinical clinical manifestation Control controls coronavirus correlated COVID-19 CSF cytokine Cytokines described discharge electrochemiluminescence assay elevated Encephalopathy FIVE full-length High-dose IFN-γ IL-1β IL-2 IL-8 Immunotherapy Inflammatory intravenous laboratory-confirmed mechanism MIG MIP-1β MIS-C N-terminal domain Neuroinflammation Neuropsychiatric occur one patient outcome pathophysiologic Patient pediatric pediatric COVID-19 Pediatric patient pro-inflammatory profile Psychiatric Psychiatric symptoms Receptor binding domain required Result retrospective SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seizures significantly steroid Steroids student Symptom Symptoms syndrome t-test tested TNF-α Tocilizumab Treatment with COVID-19
[DOI] 10.1016/j.msard.2021.103169 [Article Type] Research article

Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19

COVID-19에 대해 DNA 나노백신을 보호하고 전달하는 분리형 마이크로니들 패치

Article

Published on 2021-09-282022-09-11
Journal: ACS Nano [Category] SARS, 치료법,

Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies

피 멘타 디오카 (L.) 메르.생물 활성 성분은 항 -SARS-COV-2 및 항 염증 활성을 발휘합니다 : 분자 도킹 및 역학, 시험 관내 및 생체 내 연구

Article

Published on 2021-09-272022-08-31
Journal: Molecules [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] Pimenta Acetate acute respiratory distress anti-inflammatory agent anti-inflammatory agents anti-inflammatory effect Anti-inflammatory effects anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity Anti-viral chloride chlorogenic acid Clinical studies clinical study Combination Compound compounds Constituent coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patients Critical cytokine cytotoxicity docking and dynamics simulations Dynamics Effect ethyl acetate Evidence expression ferulic acid G-CSF gallic acid Genetic IL-10 IL-1β IL-2 Immunological response in vitro and in vivo studies Infection inhibitory concentration isolate lead life-threatening lung management mechanism of action mercuric chloride miRNA molecular docking MPro patients with COVID-19 performed RATs respiratory distress rutin SARS-CoV-2 SARS-CoV-2 main protease tested TNF-α Toxicity Treatment Viral viral infection were recorded
[DOI] 10.3390/molecules26195844 PMC 바로가기 [Article Type] Article

Site-specific PEGylation of interleukin-2 enhances immunosuppression via the sustained activation of regulatory T cells

Research

Published on 2021-09-272022-10-05
Journal: Nature biomedical engineering [Category] 치료제,

Development of a Recombinant RBD Subunit Vaccine for SARS-CoV-2

Article

Published on 2021-09-262022-10-28
Journal: Viruses [Category] COVID-19, SARS,