Landscape Profiling Analysis of DPP4 in Malignancies: Therapeutic Implication for Tumor Patients With Coronavirus Disease 2019Oncology Published on 2021-02-042022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome analyzed binding bioinformatics cancer patient cancer type caused cellular changes in characterized complications coronavirus coronavirus disease correlation COVID-19 Critical Cytokine storms datasets demonstrated Dipeptidyl peptidase 4 DPP4 enzyme II estimation expression expression levels healthy immune Immune cell Immunity immunopathological infiltrating landscape lymphopenia malignancies malignancy marker Patient patients pharmacological Pneumonia positively correlated Profiling profiling analysis receptor risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 treatment Support susceptibility therapeutic effect tissue Tumor underlying conditions [DOI] 10.3389/fonc.2021.624899 PMC 바로가기 [Article Type] Oncology
Metaplastic squamous cell breast cancer: A case report and treatment strategy during covid-19 pandemicCase Report Published on 2021-01-222022-10-04 Journal: International Journal of Surgery Case Reports [Category] 치료법, [키워드] absence Aggressive aggressiveness Breast cancer Cancer Case report Cell Chemotherapy treatment clinical COVID-19 cytological defined diagnosed Diagnosis disease form histological incidence Inflammatory initial Local malignancies metaplastic Multidisciplinary management pandemic Patient presentation radiological features Radiotherapy resulting role Spread Squamosus carcinoma squamous Squamous cell the disease the patient Treatment UIQ, upper inner quadrant UIQupper inner quadrant undergo UOQ, upper outer quadrant UOQupper outer quadrant upper inner quadrant upper outer quadrant women [DOI] 10.1016/j.ijscr.2021.01.079 PMC 바로가기 [Article Type] Case Report
Mechanistic Implications of Biomass-Derived Particulate Matter for Immunity and Immune DisordersReview Published on 2021-01-202022-10-28 Journal: Toxics [Category] COVID-19, [키워드] Affect aggravate Airway inflammation allergic diseases allergic rhinitis Asthma atopic dermatitis biomass cardiovascular diseases cause coronavirus COVID-19 disease Diseases disorder Evidence Health highlighting host defense human diseases hypersensitivity hypersensitivity disorders immune response immune system Immunity immunological immunological effect infections Intervention malignancies matter mitigate modulation molecular molecular mechanism Particulate Particulate matter Pathologies regulate risk susceptibility Tuberculosis [DOI] 10.3390/toxics9020018 PMC 바로가기 [Article Type] Review
Cancer patients and COVID-19: Mortality, serious complications, biomarkers, and ways forward암 환자와 COVID-19: 사망률, 심각한 합병증, 바이오마커, 그리고 앞으로의 길Review Published on 2021-01-012022-09-11 Journal: Cancer treatment and research communications [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus benefit Biomarkers C-reactive protein Cancer cancer patient Cancer patients complications consequence coronavirus COVID-19 COVID-19 illness COVID-19 infection Evidence evidence of hematological high risk Immunocompromised interleukin interleukin-6 leads malignancies malignancy management Mortality outcome pandemic Patient poor prognosis predictor preliminary evidence respiratory risk SARS-CoV-2 Sever acute respiratory syndrome coronavirus 2. severe complication severe complications severe COVID-19 illness severity susceptible therapeutic interventions Treatment virus with COVID-19 [DOI] 10.1016/j.ctarc.2020.100285 PMC 바로가기 [Article Type] Review
Hypercalcemia as a Biomarker of Poor Prognosis in Frail Elderly Patients with COVID-19COVID-19에 걸린 노쇠한 노인 환자의 불량한 예후의 바이오마커로서의 고칼슘혈증Article Published on 2021-01-012022-09-11 Journal: The journal of nutrition, health & aging [Category] MERS, 바이오마커, [키워드] Adults age albumin Antibiotics baseline Biomarker calcium Cardiomyopathy cohort study Concentration concentrations COVID-19 COVID-19 patients defined determine elderly elderly patients exhibited functional geriatric patients Health Hospital admission Hospitalized hypercalcemia hypertension Hypocalcemia less malignancies Mortality normocalcemia Older Older adults participant patients hospitalized Poor Prognosis respiratory SARS-CoV-2 Sex survival survival time survived were assessed with COVID-19 [DOI] 10.1007/s12603-021-1690-7 PMC 바로가기 [Article Type] Article
Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico studyResearch article Published on 2021-01-012022-10-05 Journal: Journal of Molecular Structure [Category] 신약개발, [키워드] approach binding binding energy biological system carried complexes database Degradation diabete docking docking score drug Drug repurposing evaluate FDA approved drug finding functional Heart diseases identify in-silico inhibitor inhibitors Interaction kidney Ligand malignancies molecular molecular docking molecular dynamics neprilysin Neutral obesity pathological conditions pathology peptide performed physiological Precision reported repurposing screened similarity tested therapeutic effect therapeutic target Virtual screening was used [DOI] 10.1016/j.molstruc.2020.129073 [Article Type] Research article
Characteristics of mortal COVID-19 cases compared to the survivors생존자와 비교한 사망 코로나19 사례의 특성Meta-Analysis Published on 2020-12-312022-09-10 Journal: Aging (Albany NY) [Category] SARS, 바이오마커, [키워드] addition article C-reactive protein chronic liver disease chronic obstructive chronic obstructive pulmonary disease clinician CNKI Coagulation coagulation indicators Comorbidities Comorbidity contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic D-dimer death death cases deaths Deterioration diabetes disease extracorporeal membrane oxygenation healthcare help hypertension Inflammatory indicators inflammatory markers interleukin interleukin 6 Liver disease malignancies mechanical ventilation Meta-analysis mortality rate number of deaths obstructive pulmonary disease occurred outbreak Platelet Platelet count poor prognosis predicted procalcitonin Prognosis prognosis of patients progression proportion proportions prothrombin Prothrombin time public health emergency pulmonary disease reduce risk factor Risk factors SARS-CoV-2 searched selected significantly higher Stata statistically survival cases survivor the disease Treatment triggered was performed were used with COVID-19 [DOI] 10.18632/aging.202216 PMC 바로가기 [Article Type] Meta-Analysis
Evidence-Based Strategies for the Treatment of Peritoneal Malignancies during Health Care Resource Restriction: The COVID-19 PandemicReview Published on 2020-12-012022-10-31 Journal: Current Oncology [Category] Coronavirus, MERS, SARS, [키워드] Affect affected aligned benefit Cancer Care Chemotherapy complex Course COVID-19 COVID-19 pandemic decrease disease Factors Health help hospital hospital resources Intensive literature review malignancies malignancy management multidisciplinary discussion narrative National oncologist operative outcome pandemic triage strategies Patient Patient care patients peritoneal malignancies Perspective progression recommendation resource resources Result stability Strategy surgeon surgical Surveillance thought Treatment Treatment strategies Triage unique urgency Volume was performed [DOI] 10.3390/curroncol28010006 PMC 바로가기 [Article Type] Review
Fast Clearance of the SARS-CoV-2 Virus in a Patient Undergoing Vaccine Immunotherapy for Metastatic Chordoma: A Case ReportOncology Published on 2020-11-162022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] appear Cancer cancer treatment chordoma complications Coronavirus disease 2019 COVID-19 pandemic death diagnosed with COVID-19 disease disease course Effect functional greater illness immune system Immunocompromised Immunosuppressed Immunosuppression Immunotherapy individual Infection intravenous malignancies metastatic Mild modified vaccinia Ankara-brachyury vaccine multi-organ failure non-specific Pain Population receiving report respiratory complaint resulting risk SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 significantly suggested Symptom the patient the SARS-CoV-2 the SARS-CoV-2 virus therapy thought Treatment Vaccine virus while [DOI] 10.3389/fonc.2020.603248 PMC 바로가기 [Article Type] Oncology
T cell regeneration after immunological injury Reviews Published on 2020-10-232022-10-05 Journal: Nature reviews. Immunology [Category] 바이오마커, [키워드] adaptive approach benefit cause cell stress Chemotherapy clinical consequences consequence de novo Delayed ENhance immune immune function immune system Immunity immunological Immunosuppression increased risk individual Infection Injury malignancies outcome Patient promote Radiotherapy review T cell T cells therapeutic strategy thymic vaccine response [DOI] 10.1038/s41577-020-00457-z [Article Type] Reviews