Current status of mesenchymal stem cell therapy for immune/inflammatory lung disorders: Gleaning insights for possible use in COVID ‐19Concise Review Published on 2020-06-112022-10-28 Journal: Stem cells translational medicine [Category] COVID-19, MERS, [키워드] accompanied accumulated acute respiratory distress Allogeneic ARDS Asthma Bacterial bacterial pneumonia chronic obstructive clinical trial Clinical use COPD COVID COVID‐19 COVID‐19 curative current Cytokine storm disease Diseases disorder disorders Effect effective Evidence Gleaning Idiopathic pulmonary fibrosis immunomodulatory property Influenza lack lung lung disorders mesenchymal stem cell Mesenchymal stem cells mortality rate MSC MSC therapy MSCs novel coronavirus disease outcomes pandemic Perspective preclinical data pulmonary conditions pulmonary disease pulmonary injury regenerative reported stem cell Stem cell therapy syndrome therapeutic therapeutic use therapy [DOI] 10.1002/sctm.20-0186 PMC 바로가기 [Article Type] Concise Review
Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics급성호흡곤란증후군의 간엽줄기세포치료제: 기초부터 임상까지Review Published on 2020-06-092022-09-10 Journal: Protein & Cell [Category] MERS, SARS, 비임상, [키워드] 2019 novel coronavirus 2019 novel coronavirus disease acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alveolar fluid clearance anti-apoptotic Anti-inflammatory approaches ARDS Bacterial breath caused Cell cell damage Cell therapy China clinical study clinics coronavirus coronavirus disease COVID-19 COVID-19 patient develop disease disrupt distal Effects Efficacy ENhance epithelial epithelial cell event Extracellular vesicles Factor high mortality intrinsic limit lung mechanism mesenchymal stem cell Mesenchymal stem cells morbidity MSC MSC therapy multiple organ failure Novel coronavirus novel coronavirus disease occurred optimization Organ failure organ injury paracrine pathophysiological patients with ARDS Pneumonia promote pulmonary endothelial respiratory respiratory distress SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV-2-infected patients severe acute respiratory syndrome Coronavirus severe pneumonia stem cell supportive care survival syndrome therapeutic therapy variety [DOI] 10.1007/s13238-020-00738-2 PMC 바로가기 [Article Type] Review
Intravenous infusion of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells as a potential treatment for patients with COVID-19 pneumoniaCase Reports Published on 2020-05-272022-10-06 Journal: Stem Cell Research & Therapy [Category] MERS, SARS, 진단, [키워드] C-reactive protein CD3 CD4 CD8 China COVID-19 COVID-19 pathogenesis discharged drug effective global public health healthy donor highlight Human umbilical cord Wharton’s jelly-derived MSCs IL-6 immune system immunomodulatory Infection Inflammation intravenous intravenous infusion Liaocheng Lymphocyte subset mesenchymal stem cell MSC MSCs novel coronavirus disease Patient patients with COVID-19 Pneumonia Potential treatment Pulmonary function Safe severe COVID-19 shown significantly stem cell Symptom T cell the patient TNF-α treated Treatment treatment for COVID-19 umbilical Vaccine Wharton’s jelly-derived MSC with COVID-19 Wuhan, China [DOI] 10.1186/s13287-020-01725-4 PMC 바로가기 [Article Type] Case Reports
Hypothesis for the management and treatment of the COVID-19-induced acute respiratory distress syndrome and lung injury using mesenchymal stem cell-derived exosomesArticle Published on 2020-05-222023-06-16 Journal: Medical Hypotheses [Category] MERS, [키워드] acute respiratory distress syndrome COVID-19 Exosomes mesenchymal stem cell SARS-CoV-2 [DOI] 10.1016/j.mehy.2020.109865 PMC 바로가기 [Article Type] Article
Mesenchymal stem cells as a potential therapy for COVID-19Commentary Published on 2020-05-042022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, MERS, [키워드] 2019 novel coronavirus ALI ARDS cause cellular characterized clinical trial COVID-19 Critical disease distress effective hyaline membrane formation Inflammatory response lung mesenchymal stem cell MSC MSCs outbreak pathologic feature potential therapy presenting Pulmonary edema pulmonary inflammation raise Severe case specific treatment syndrome therapy Treatment [DOI] 10.1186/s13287-020-01678-8 PMC 바로가기 [Article Type] Commentary
Mesenchymal Stem Cell Therapy for COVID-19: Present or FutureArticle Published on 2020-04-132023-07-02 Journal: Stem cell reviews and reports [Category] SARS, [키워드] clinical trials coronavirus COVID-19 immunomodulatory mesenchymal stem cell Stem cell therapy [DOI] 10.1007/s12015-020-09973-w PMC 바로가기 [Article Type] Article
Transplantation of ACE2 – Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 PneumoniaOrginal Article Published on 2020-04-092022-10-06 Journal: Aging and Disease [Category] 진단, [키워드] ACE2 ACE2 negative addition adverse effect adverse effects Beijing C-reactive protein caused cell population cell transplantation change China clinical outcomes control group coronavirus COVID-19 COVID-19 infection discharged effective enrolled function recovery functional gene expression profile IL-10 Immune cell immune function immunomodulation immunomodulatory IMPROVE indicated Inflammatory injection intravenous mesenchymal stem cell Mesenchymal stem cells MSC MSCs NK cell novel coronavirus disease outbreak outcome Patient patients with COVID-19 peripheral lymphocyte Placebo Pneumonia Preventing Pulmonary function Regulatory Safe Seven Severe COVID-19 pneumonia Severe patient shown significantly STEM Symptom T cells the cytokine storm the patient TMPRSS2 TNF-α transplantation Treatment treatment group were assessed with COVID-19 Wuhan, China [DOI] 10.14336/AD.2020.0228 PMC 바로가기 [Article Type] Orginal Article
Feasibility of Mesenchymal Stem Cell Therapy for COVID-19: A Mini ReviewCOVID-19에 대한 중간엽 줄기세포 치료의 타당성: 미니 리뷰Review Published on 2020-01-012022-09-11 Journal: Current gene therapy [Category] SARS, 유전자 메커니즘, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome addition Anti-inflammatory anti-SARS-CoV-2 ARDS Complication coronavirus disease Coronavirus disease 2019 COVID-19 CSS current cytokine Cytokine storm Cytokine storm syndrome Cytokine storms drug dysregulated Fatality rate functions immune immune function Immunity infected with SARS-CoV-2 inhibiting Lung injury mesenchymal stem cell Mesenchymal stem cells MINI MSC MSCs organ organs Patient patients potential mechanism reduce regulate Regulatory repair Research respiratory distress restoration review risk Secretome severe complication severe complications Severe patient STEM stem cells syndrome T cell T cells therapeutic effect therapeutic effects tissue tissue damage treating COVID-19 Treatment Vaccine [DOI] 10.2174/1566523220999200820172829 PMC 바로가기 [Article Type] Review
A study about immunomodulatory effect and efficacy and prognosis of human umbilical cord mesenchymal stem cells in patients with chronic hepatitis B-induced decompensated liver cirrhosisArticle Published on 2018-04-012023-06-19 Journal: Journal of gastroenterology and hepatology [Category] B형 간염, [키워드] cytokine Decompensated liver cirrhosis Efficacy immunomodulatory Lymphocyte subsets mesenchymal stem cell Prognosis [DOI] 10.1111/jgh.14081
Umbilical Cord-Derived Mesenchymal Stem Cell Transplantation in Hepatitis B Virus Related Acute-on-Chronic Liver Failure Treated with Plasma Exchange and Entecavir: a 24-Month Prospective StudyArticle Published on 2016-12-012023-06-16 Journal: Stem cell reviews and reports [Category] B형 간염, [키워드] Acute-on-chronic liver failure Antiviral agents Hepatitis B virus mesenchymal stem cell plasma exchange [DOI] 10.1007/s12015-016-9683-3