Circulating Levels of Interleukin-6 and Interleukin-10, But Not Tumor Necrosis Factor-Alpha, as Potential Biomarkers of Severity and Mortality for COVID-19: Systematic Review with Meta-analysisCOVID-19의 심각도 및 사망률에 대한 잠재적 바이오마커로서 Interleukin-6 및 Interleukin-10의 순환 수준(종양 괴사 인자-알파 아님): 메타 분석을 통한 체계적 검토Meta-Analysis Published on 2021-01-012022-09-11 Journal: Journal of Clinical Immunology [Category] SARS, 바이오마커, [키워드] 95% CI acute respiratory distress Alpha association Biomarker Biomarkers circulating Cochrane Library contributing to COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients cytokine Cytokine storm Cytokines database determine disease severity elevated eligible hand highlighting IL-10 IL-6 inception Inflammatory cytokine Inflammatory cytokines interleukin interleukin-10 interleukin-6 Level manifestation mean difference Meta-analysis meta-regression Mortality non-survivor performed Potential publication bias Quality random-effects model Regression respiratory distress review Sensitivity analyses sensitivity analysis severe COVID-19 patient severe COVID-19 patients severe manifestations of COVID-19 severity significantly significantly increased survivor syndrome systematic review systemic inflammatory response systemic level the disease therapeutic target TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-alpha was performed [DOI] 10.1007/s10875-020-00899-z PMC 바로가기 [Article Type] Meta-Analysis
A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment코로나19 치료에서 클로로퀸과 하이드록시클로로퀸 단독요법 또는 아지스로마이신과의 병용요법에 대한 체계적인 검토 및 메타분석Meta-Analysis Published on 2020-12-172022-09-10 Journal: Scientific Reports [Category] SARS, 임상, 치료법, 치료제, [키워드] 95% CI 95% confidence interval Analysis article Azithromycin calculated can not carried Chain Reaction Chloroquine CIs Combination coronavirus COVID-19 cure rate database Diseases drug side effects Effect Effectiveness examined exposure to Future good quality group HCQ Hospital stay Hydroxychloroquine IMPROVE Infectious diseases investigated mechanical ventilation Meta-analysis meta-regression monotherapy Mortality mortality rate not differ not different observational studies observational study Patient PCR polymerase chain polymerase chain reaction radiological improvement radiological progression random-effects model randomized control trial RCT relative risks reported risk RRs scarcity side Side effects significantly significantly higher standard care statistically systematic review treating COVID-19 Treatment Viral viral infection was performed worsening [DOI] 10.1038/s41598-020-77748-x PMC 바로가기 [Article Type] Meta-Analysis
The prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients: a systematic review and meta-regressionResearch Published on 2020-12-172022-10-31 Journal: Human Resources for Health [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV 95% CI Analysis Anxiety approach collected Comprehensive conducted COVID-19 COVID-19 patient COVID-19 patients Data analysis Depression determine disorder Google Scholar Health healthcare worker Healthcare workers heterogeneity Hospital staff ISI lack measure Mental Mental disorder mental illness Meta-analysis meta-regression performed Prevalence Prevent psychiatrists psychologists random effect reported Research Result Sample size SARS-CoV-2 statistically significant Stress systematic review total sample size Web of Science were used [DOI] 10.1186/s12960-020-00544-1 PMC 바로가기 [Article Type] Research
COVID-19 and Acute Kidney Injury: A Systematic Review and Meta-AnalysisReview Published on 2020-12-152022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] 95% CI Acute kidney injury adopted age AKI analyses Arterial hypertension calculated caused clinical study coronavirus disease COVID-19 COVID-19 patient COVID-19 positive patient death Deceased dialysis Egger’s test evaluate Frequency greater heterogeneity Hospitalization hospitalized COVID-19 incidence Kidney injury mechanism Meta-analysis meta-regression morbidity and mortality Mortality occurred Occurrence Odds ratio outcomes pandemic Patient patients patients with COVID-19 performed positive patients preliminary evidence random-effects model renal replacement therapy retrieved review risk RRT SARS-CoV-2 severe COVID-19 severe disease Significant stratified Survivors systematic review unique [DOI] 10.3390/pathogens9121052 PMC 바로가기 [Article Type] Review
Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implicationsMeta-Analysis Published on 2020-12-082022-10-31 Journal: European Journal of Epidemiology [Category] COVID-19, MERS, SARS, [키워드] Adults age Analysis articles Assessing children collected COVID-19 deaths decrease fatality Fatality rate fixed geographical location geographical locations Government greater group groups help IFR implication inclusion criteria increase Infection Infection-fatality rate Infection-fatality ratio infections intrinsically magnitude Meta-analysis meta-regression mitigate Older parameter Prevalence PROTECT public health public health measure reflect reported risk SARS-CoV-2 Seasonal influenza specificity supplementary material Systematic review systematic review Variation virus were used [DOI] 10.1007/s10654-020-00698-1 PMC 바로가기 [Article Type] Meta-Analysis
Random effects meta-analysis of COVID-19/S. aureus partnership in co-infectionArticle Published on 2020-11-272022-11-01 Journal: GMS Hygiene and Infection Control [Category] COVID-19, [키워드] 95% CI Analysis analyzed antibiotic anticipated articles Bacterial calculated clinician Co-infection conducted correlation country covariate COVID-19 COVID-19 patient database Diagnosis Effect effect size Egger estimate evaluate exacerbate fungal heterogeneity Hypothesis Improved median Meta-analysis meta-regression meta-regression model morbidity and mortality MRSA outcome Patient patients patients hospitalized performed pooled rate Population positive proportion Q statistic random effect ranged REM reported retrieved rRT-PCR S. aureus SARS-CoV-2 searched significantly Support tested Variability were used with COVID-19 [DOI] 10.3205/dgkh000364 PMC 바로가기 [Article Type] Article
Risk Factors for Severe Disease and Efficacy of Treatment in Patients Infected With COVID-19: A Systematic Review, Meta-Analysis, and Meta-Regression AnalysisCOVID-19에 감염된 환자의 중증 질병 및 치료 효능에 대한 위험 요인: 체계적인 검토, 메타 분석 및 메타 회귀 분석Meta-Analysis Published on 2020-11-192022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome Admission Alanine alanine aminotransferase ARDS aspartate Aspartate transaminase benefit clinical feature conducted coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroids COVID-19 Efficacy elevated elevated lactate dehydrogenase Factor ICU ICU admission intensive care intensive care unit Lactate lactate dehydrogenase LDH leukocyte Lopinavir Lopinavir-ritonavir Meta-analysis meta-regression Mortality outcomes pandemic pandemic spread Patient Pooled rates predicted predictor present procalcitonin reported respiratory distress Respiratory distress syndrome review risk risk factor Ritonavir severe severe disease Spread syndrome systematic review Treatment [DOI] 10.1093/cid/ciaa576 PMC 바로가기 [Article Type] Meta-Analysis
Nucleic acid amplification tests on respiratory samples for the diagnosis of coronavirus infections: a systematic review and meta-analysisSystematic Review Published on 2020-11-112022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, SARS, [키워드] Accuracy acute respiratory syndrome acute respiratory tract infection affecting amplification assessment average can be used clinical samples Cochrane Library confidence coronavirus coronavirus disease Coronavirus infection Coronavirus infections COVID-19 defined diagnosed Diagnosis diagnostic eligibility eligible evaluate evaluated Grey high risk isothermal amplification Lower respiratory tract Meta-analysis meta-regression NAAT nucleic acid amplification nucleic acid amplification tests objective participant Patient PCR PCR assay PCR tests pooling Quality RdRP real-time RT-PCR reference reference standard Region reported respiratory sample Result RNA-dependent RNA polymerase RT-LAMP S gene SARS-CoV-2 sensitivity Sensitivity and specificity significantly higher significantly lower specificity systematic review transcriptase variable Web of Science [DOI] 10.1016/j.cmi.2020.11.002 PMC 바로가기 [Article Type] Systematic Review
Predictors of in-hospital COVID-19 mortality: A comprehensive systematic review and meta-analysis exploring differences by age, sex and health conditions병원 내 COVID-19 사망률 예측인자: 연령, 성별 및 건강 상태에 따른 차이를 탐색하는 포괄적인 체계적인 검토 및 메타 분석Research Article Published on 2020-11-032022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, [키워드] addition age albumin ALT applied AST Bilirubin C-reactive protein cardiac troponin Cardiac troponin I clinical condition clinical conditions Comorbidities Comorbidity Concentration conditions conducted confirmed COVID-19 patients COVID-19 COVID-19 mortality COVID-19 patient creatinine Critical database deaths diabete diabetes Dyspnoea effect size Factor ferritin followed by Haemoglobin Health health condition heterogeneity hospital hypertension In-hospital in-hospital mortality increased mortality interleukin-6 Kidney disease laboratory parameter Laboratory parameters LDH malignancy meta-analyses Meta-analysis meta-regression Mortality nitrogen obesity objective Odds ratio older patient older patients Patient patients Platelet Platelet count populations predictor predictors prognostic effect pulmonary disease random-effects meta-analyses registration number Result risk Sex smoking Subgroup analyses subgroup analysis systematic review the mean the MEDLINE total bilirubin troponin I urea urea nitrogen variable Web of Science [DOI] 10.1371/journal.pone.0241742 PMC 바로가기 [Article Type] Research Article
Association of cardiac biomarkers and comorbidities with increased mortality, severity, and cardiac injury in COVID-19 patients: A meta-regression and decision tree analysisCOVID-19 환자의 사망률, 중증도 및 심장 손상이 증가한 심장 바이오마커 및 동반 질환의 연관성: 메타 회귀 및 의사 결정 트리 분석Meta-Analysis Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] 바이오마커, 진단, [키워드] 95% CI 95% confidence interval advanced age adverse outcome adverse outcomes Analysis applied aspartate Aspartate aminotransferase assessment association AST best Biomarker cardiac injury cardiac marker Cardiac markers cardiac troponin cardiovascular disease cardiovascular diseases cardiovascular system characteristic CIs clinical feature Comorbidity coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 severity Cutoff Decision tree Deleterious develop elevated highest IMPROVE increased mortality Injury Laboratory lead Meta-analysis meta-regression Mortality mortality rate myocardial injury Odds ratio outcome outcomes Patient patients with COVID-19 predict prognostic receiver operating characteristic risk SARS-CoV-2 severity SMD standardized mean difference therapeutic approaches threshold troponin I [DOI] 10.1002/jmv.26166 PMC 바로가기 [Article Type] Meta-Analysis