Effect of ambient temperature on respiratory tract cells exposed to SARS-CoV-2 viral mimicking nanospheres-An experimental studySARS-CoV-2 바이러스 모방 나노스피어에 노출된 호흡기 세포에 대한 주변 온도의 영향-실험 연구Article Published on 2021-01-282022-09-12 Journal: Biointerphases [Category] 진단, [키워드] ACE-2 ACE-2 receptor acute respiratory syndrome airway epithelial cell ambient angiotensin-converting enzyme 2 binding bovine Calu-3 caused change coated with Community coronavirus country denaturing Effect fibroblast cell fluctuation had no Host host cell incubated indicated infect Infection Infectious disease Interaction lung epithelia mimicking modulated nonspecific Novel coronavirus occurred pandemic Polymer Protein RBD reached reported respiratory tract respiratory tract cell S protein S-RBD SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 viral seasonal serum Spread stability surface receptor temperature the S protein the SARS-CoV-2 Transmission Viral transmission virus [DOI] 10.1116/6.0000743 PMC 바로가기 [Article Type] Article
Caged Dexamethasone/Quercetin Nanoparticles, Formed of the Morphogenetic Active Inorganic Polyphosphate, are Strong Inducers of MUC5ACArticle Published on 2021-01-272022-10-30 Journal: Marine Drugs [Category] COVID-19, [키워드] A549 cell addition airway alveolar antiviral activity ATP Bacteria caused cells Compound Concentration coronavirus disease coronavirus SARS-CoV-2 COVID-19 Defense Dexamethasone drug Effect epithelial exhibit expression Gene Expression glycoprotein human alveolar basal epithelial A549 cells human cells hydrolysis impair inorganic mechanism metabolic energy metabolite MUC5AC mucin Nanoparticles oxygen Pathogenesis patients Platelet Polymer polyphosphate Protective quercetin Release respiratory epithelium SARS-CoV-2 scavenging secreted significantly higher significantly increased Strong syndrome [DOI] 10.3390/md19020064 PMC 바로가기 [Article Type] Article
Morphogenetic (Mucin Expression) as Well as Potential Anti-Corona Viral Activity of the Marine Secondary Metabolite Polyphosphate on A549 CellsA549 세포에 대한 해양 2차 대사산물 폴리포스페이트의 형태유전학적(뮤신 발현) 및 잠재적인 항-코로나 바이러스 활성Article Published on 2020-12-142022-09-10 Journal: Marine Drugs [Category] MERS, SARS, 바이오마커, [키워드] A549 A549 cell ACE2 receptor activity addition adenylate kinase ADK alkaline phosphatase ALP alveolar antiviral response ATP attachment Bacteria binding block Blood Blood platelets Bronchial epithelium Cell cell growth cells cellular collagen coronavirus coronavirus SARS-CoV-2 epithelial Express expression Extracellular extracellular ATP growth human alveolar cells hydrogel immunostaining in vitro in vivo Inhaled inhibiting Innate immunity involved metabolic energy MUC1 MUC5AC mucin mucins nasopharynx nontoxic pathogen Pathogens phosphatase physiological Platelets Polymer polyp polyphosphate Potential protective effect Proteins RBD Receptor binding domain reduction in released SARS-CoV-2 spike protein secondary secreted significantly increased stimulated strength the cells These cells Viral viral RBD virus well [DOI] 10.3390/md18120639 PMC 바로가기 [Article Type] Article
COVID-19 Infection Detection and Prevention by SARS-CoV-2 Active Antigens: A Synthetic Vaccine ApproachCommunication Published on 2020-11-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome antibody Antigen antigen design antigen processing approach bioinformatics component components coronavirus COVID-19 deaths demonstrated detection Evidence form global pandemic HLA Human human population humoral immune response knowledge Ligand long-lasting mechanism MHC-I monomer Polymer prevention produced reactivity reported RNA Safe SARS-CoV-2 sequence sera specificity synthetic synthetic-vaccine candidate tested Vaccines Viral vector virus virus genomes virus infection was performed [DOI] 10.3390/vaccines8040692 PMC 바로가기 [Article Type] Communication
Smart polymeric eye gear: A possible preventive measure against ocular transmission of COVID-19스마트 폴리머 아이 기어: COVID-19의 안구 전염에 대한 가능한 예방 조치Article Published on 2020-11-012022-08-31 Journal: Medical Hypotheses [Category] 치료제, [키워드] ACE ACE-2 ACE-2 receptor angiotensin Angiotensin-converting enzyme antiviral activities antiviral activity appear attribute binding binding affinity Complete Concentration congestion conjunctival COVID-19 COVID-19 transmission description Evidence evidence of eye Eye infection Face shield functional healthcare Healthcare workers host cells Hypothesis identify IMPROVE In-vitro leads ocular Ocular surface offer Polymer prophylactic measure prophylactic measures Prophylaxis Protective receptor receptors reported Safe SmaRT suggested susceptibility Transmission virus entry [DOI] 10.1016/j.mehy.2020.110288 PMC 바로가기 [Article Type] Article
The effect of temperature on persistence of SARS-CoV-2 on common surfacesResearch Published on 2020-10-072022-10-28 Journal: Virology Journal [Category] COVID-19, MERS, SARS, [키워드] calculated carried contaminated surfaces COVID-19 determine Effect effect of temperature elevated environmental stability experiment globe highest incubated Infectious virus initial viral load less patients persistence Polymer Prevent reducing required Result risk SARS-CoV-2 significantly Spread spread of COVID-19 stability Survivability survival rate survived temperature titre Transmission UV light virus while [DOI] 10.1186/s12985-020-01418-7 PMC 바로가기 [Article Type] Research
Gas Plasma Technology—An Asset to Healthcare During Viral Pandemics Such as the COVID-19 Crisis?Article Published on 2020-07-162022-10-29 Journal: Ieee Transactions on Radiation and Plasma Medical Sciences [Category] COVID-19, [키워드] Airborne virus Bacteria cold atmospheric pressure plasma COVID-19 COVID-19 crisis Critical DBD decontamination healthcare Healthcare system inactivation include instances Laboratory majority management pandemic Pandemics Perspective plasma plasma jet Polymer reduction Safe Spread targets tissues Transmission Viral load virus inactivation viruses [DOI] 10.1109/TRPMS.2020.3002658 PMC 바로가기 [Article Type] Article
Biofilm-associated toxin and extracellular protease cooperatively suppress competitors in Bacillus subtilis biofilms생물막 관련 독소 및 세포외 프로테아제는 Bacillus subtilis 생물막에서 경쟁자를 협력적으로 억제합니다Research Article Published on 2019-10-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] aggregate Alter antibiotic Antibiotics Antimicrobials assistance B . subtilis Bacillus subtilis Bacteria Bacterial bacterial composition biofilm Cell cells combating contribute Defense DEGs demonstrated diffusion Diseases effective eliminated excluded expression Extracellular food contamination growth impair Infectious diseases inhibit leads medium multicellular mutant mutations Neutral observation overexpression penetrate peptide Polymer polymers Prevent problem problems protease PROTECT Protein Regulatory required resistance gene resistance genes secreted solid medium Space suppress Taking Tolerance Treatment type strain upstream wild-type strain [DOI] 10.1371/journal.pgen.1008232 PMC 바로가기 [Article Type] Research Article
Histopathologic Evaluation of Polymer Supports for Pintucci-type Keratoprostheses: An Animal StudyOriginal Article Published on 2019-07-182024-09-02 Journal: Journal of Ophthalmic & Vision Research [Category] 대상포진, [키워드] Fibrovascular Tissue Ingrowth Keratoprosthesis Pintucci Polymer [DOI] 10.18502/jovr.v14i3.4779 PMC 바로가기 [Article Type] Original Article
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expressionResearch Article Published on 2019-05-162022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] abundantly expressed activity addition ADP-ribose ADP-ribosylation Affect antiviral activities Antiviral effect antiviral therapy cellular Coronaviridae coronavirus Coronavirus replication Critical disease enzyme expression facilitate host cell host response human cells identify IFN immune response in vivo independent inhibited inhibitor Innate immunity interferon knockdown less macrodomain Macrophage mice Modification monomer murine mutant mutant virus Mutation PARP PARP12 PARP14 PARPs pathogenic Polymer post-translational modification Prevent Protein Regulation Replication required significantly siRNAs target protein These data Togaviridae virulence virus virus infection virus replication Virus-host interaction viruses while wild-type wild-type virus [DOI] 10.1371/journal.ppat.1007756 PMC 바로가기 [Article Type] Research Article