Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and corticosteroidsArticle Published on 2020-05-082022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 임상, 치료법, [키워드] accelerate anti-IL6 antibody benefit cell entry Characteristics clinical benefit Controlled clinical trial correlated Corticosteroid Corticosteroids COVID-19 COVID-19-related death cytokine essential element fatal disease humans Hypothesis IL6 immune system Immunoglobulin immunoglobulins immunosuppressive IMPROVE Inflammation interleukin 6 monoclonal antibody Novel coronavirus outcomes Patient patients with COVID-19 pro-inflammatory cytokine Prognosis prognosis of patient rationale reduce SARS-CoV2 severe COVID-19 severity shown target targeted therapy therapeutic option therapy Treatment use of corticosteroid Viral load with COVID-19 [DOI] 10.1016/j.intimp.2020.106560 PMC 바로가기 [Article Type] Article
C‐reactive protein correlates with computed tomographic findings and predicts severe COVID‐19 earlyC 반응성 단백질은 컴퓨터 단층 촬영 결과와 상관 관계가 있으며 심각한 COVID-19를 조기에 예측합니다Research Article Published on 2020-04-252022-09-25 Journal: Journal of medical virology [Category] SARS, 바이오마커, 진단, [키워드] 95% CI Analysis Biomarker C‐reactive protein C‐reactive protein characteristic Characteristics clinical parameter collected computed tomographic Computed tomography consecutive patient correlated COVID‐19 COVID‐19 patient COVID‐19 Critical CRP CRP level CT findings demonstrated differential diagnosis disease disease course electronic medical records enrolled erythrocyte sedimentation rate flu granulocyte identify initial lymphocyte Medical resources Mild Patient predict predicted Prognosis prognosis of patient progression progression stage SARS‐COVID‐2 Sensitivity and specificity severe group severity scores significantly stages WBC [DOI] 10.1002/jmv.25871 PMC 바로가기 [Article Type] Research Article
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisalResearch Published on 2020-04-072022-10-28 Journal: The BMJ [Category] COVID-19, [키워드] adhere age benefit blood pressure body temperature Computed tomography scans control patients coronavirus disease creatinine critical appraisal data extraction develop diagnosing Diagnosis diagnostic estimate event Evidence exclusion feature General population Guidance high risk hospital Hospital admission Hospital stay Immediate include increased risk indicate Infection mortality risk MOST multivariable objective occur outcome overfitting OVID Patient Pneumonia prediction predictor Prognosis prognosis of patient prognostic prognostic model progression ranged reported Result risk of bia Risk of bias screened severe disease Sex study population Support Symptoms systematic review the disease [DOI] 10.1136/bmj.m1328 PMC 바로가기 [Article Type] Research
Roles of TNF -α gene polymorphisms in the occurrence and progress of SARS-Cov infection: A case-control studyResearch Article Published on 2008-02-292022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] 95% CI acute respiratory syndrome adjusted Analysis association carried case-control study collected data compared conducted cured determine discharged fibrosis found Genetic polymorphism Genotype glucocorticoid Health care worker healthy controls Host genetic factor Infection interstitial locus Logistic lung Lung fibrosis manifested Necrosis not affect Occurrence PCR polymorphism prognosis of patient promoter region protective effect relationship Result risk risk factor role SARS patient SARS patients SARS-CoV infection Sequencing SNP susceptibility TNF TNF-α was used [DOI] 10.1186/1471-2334-8-27 PMC 바로가기 [Article Type] Research Article