Fair and equitable subject selection in concurrent COVID-19 clinical trials동시 코로나19 임상시험에서 공정하고 공평한 피험자 선정Article Published on 2021-01-012022-09-11 Journal: Journal of medical ethics [Category] SARS, 임상, [키워드] applicability clinical clinical trial clinical trials COVID-19 COVID-19 pandemic Critical determine disease distribution Drawing equity ethical guideline ethics committee Fair Impact International lack MONITOR policy guidelines/inst. review boards/review cttes protocol Regulation Research Research design Research Ethics risk scarcity subject Therapies therapy Transparency Trial trials USA while [DOI] 10.1136/medethics-2020-106590 PMC 바로가기 [Article Type] Article
Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII)COVID-19로 인한 입원 후 삶의 질과 장기적인 결과: 전향적 코호트 연구를 위한 프로토콜(연합 VII)Multicenter Study Published on 2021-01-012022-09-10 Journal: Revista Brasileira de Terapia Intensiva [Category] MERS, 임상, [키워드] activity acute illness all-cause mortality Anxiety approved association Brazil Cardiovascular events caused Characteristics Coalition conferences COVID-19 COVID-19 treatment Daily daily living demographic characteristics Depression disorder dissemination Dyspnea Effect Ethics ethics committee Factor FIVE functional Functional status Generalized Health Hospitalization Impact include Instrumental life Medical Research Council Medidas de resultados relatados pelo paciente Modified Medical Research Council Dyspnea Scale multicenter outcome outcomes Patient-reported outcome measures peer-reviewed performed physical Posttraumatic Stress posttraumatic stress disorder premorbid Primary outcome prospective cohort study Qualidade de vida Quality Quality of life randomized clinical trial Research Ethics Research Ethics Committee SARS-CoV-2 SARS-COV-2 infection scale secondary Study protocol survivor Symptom utility variable variables ventilatory support Visual [DOI] 10.5935/0103-507X.20210003 PMC 바로가기 [Article Type] Multicenter Study
Payment in challenge studies: ethics, attitudes and a new payment for risk modelFeature Article Published on 2020-12-252022-10-30 Journal: Journal of medical ethics [Category] COVID-19, MERS, SARS, [키워드] accounted approach avoidance calculated circulating Coercion Controlled COVID-19 pandemic determine disease empirical finding employment Guidance healthy Human Infection Model Pain participant Participants Research Research Ethics risk statistical Support urgency utility Vaccine development [DOI] 10.1136/medethics-2020-106438 PMC 바로가기 [Article Type] Feature Article
Psychosocial and health behavioural impacts of COVID-19 pandemic on adults in the USA: protocol for a longitudinal cohort study미국 성인에 대한 COVID-19 대유행의 심리사회적 및 건강 행동 영향: 종단적 코호트 연구를 위한 프로토콜Article Published on 2020-12-222022-09-11 Journal: BMJ Open [Category] SARS, 변종, [키워드] alternative method alternative methods analysed approval assessment tools association baseline behavioural can be used cause college Complete conducted contribute COVID-19 COVID-19 pandemic Cross-sectional analyses cross-sectional analysis deleterious effect deleterious effects Descriptive statistics determine Effect English Ethics Factor Health help Impact individual information institutional review board Intervention loneliness longitudinal longitudinal cohort study media Medicine Mental mental health moderate non-parametric test non-parametric tests pandemic performed predictor protocol Psychological Psychosocial public health public health messaging recruited Research Ethics social distancing social isolation social media Social support Spanish spread of COVID-19 Stress study period subgroup Support trajectory [DOI] 10.1136/bmjopen-2020-044642 PMC 바로가기 [Article Type] Article
Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccinesArticle Published on 2020-12-132023-06-16 Journal: Journal of medical ethics [Category] MERS, SARS, [키워드] clinical trials Ethics philosophical ethics Research Ethics [DOI] 10.1136/medethics-2020-106501 PMC 바로가기
Study protocol for resolution of organ injury in acute pancreatitis (RESORP): an observational prospective cohort study급성 췌장염(RESORP)의 장기 손상 해결을 위한 연구 프로토콜: 관찰 전향적 코호트 연구Observational Study Published on 2020-12-072022-09-10 Journal: BMJ Open [Category] Fulltext, MERS, SARS, 임상, 치료기술, [키워드] acute pancreatitis adult intensive & critical care Analysis assessment biochemical Cancer cardiopulmonary exercise testing cardiovascular Caregivers cellular senescence Clinical research cognitive Cognitive function Cohort diabetes Diabetes Mellitus disease dissemination echocardiography episode episode of Ethics ethics committee explain Follow-up Gastrointestinal general diabetes General population hospital incidence individual IRAS life liver mechanism MRI number organ organ dysfunction organ injury organ system outcome measure pancreatic disease participant Patient physiological predictor Premature primary outcome measure prospective cohort study protocol Pulmonary function testing Quality Quality of life receiving recruitment registration numbers registry renal renal disease Research Research Ethics researchers respiratory Result secondary secondary outcome measures severity survival Survivors undergo university university hospital [DOI] 10.1136/bmjopen-2020-040200 PMC 바로가기 [Article Type] Observational Study
Clinical Trials [and Tribulations]: The Immediate Effects of COVID-19 on IBD Clinical Research Activity in the UK임상 시험 [및 고난]: 영국의 IBD 임상 연구 활동에 대한 COVID-19의 즉각적인 영향Article Published on 2020-12-022022-09-11 Journal: Journal of Crohn's & colitis [Category] 임상, [키워드] activity Analysis Care clinical clinical care clinical pathways Clinical research clinical trial clinical trials consequence country COVID-19 Effect effective effort focus Health Health care highlighting IBD Immediate Impact implication management offer pandemic Pathways Patient Perspective Reporting Research Research Ethics Safe SARS-CoV-2 therapeutic option therapy Trial [DOI] 10.1093/ecco-jcc/jjaa137 PMC 바로가기 [Article Type] Article
Randomised controlled trial for high-dose intravenous zinc as adjunctive therapy in SARS-CoV-2 (COVID-19) positive critically ill patients: trial protocolSARS-CoV-2(COVID-19) 양성 중환자에서 보조 요법으로 고용량 아연 정맥 주사에 대한 무작위 대조 시험: 시험 프로토콜Article Published on 2020-12-022022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] Analysis caused Controlled trial coronavirus COVID-19 Critically ill demonstrated discharge distress double-blind duration of follow-up Effect Elemental end-organ Ethical approval Ethics ethics committee evaluate healthcare High-dose hospitalised patient Human hypoxic independent Infectious diseases Injury International intravenous lowest oxygen saturation mechanism non-ventilated patient non-ventilated patients oxygen oxygen saturation oxygen saturations oxygen supplementation Oxygenation pandemic PaO participant peer-reviewed Placebo positive primary outcome measure Primary outcome measures protective effect public health randomised controlled trial recruited recruitment reduction registration number Research Ethics respiratory respiratory distress Respiratory distress syndrome Respiratory illness respiratory infections Result resulting RNA polymerase robust SARS-CoV-2 SARS-COV-2 infection syndrome therapy Treatment trial protocol Vaccine ventilated patient ventilated patients Viral viral respiratory infection viral respiratory infections Virology was obtained Zinc [DOI] 10.1136/bmjopen-2020-040580 PMC 바로가기 [Article Type] Article
The carnage of substandard research during the COVID-19 pandemic: a call for qualityArticle Published on 2020-12-012023-07-06 Journal: Journal of medical ethics [Category] SARS, [키워드] Epidemiology Public health ethics Research Ethics [DOI] 10.1136/medethics-2020-106494
Uncertainty, error and informed consent to challenge trials of COVID-19 vaccines: response to Steel et al불확실성, 오류 및 COVID-19 백신 시도에 대한 정보에 입각한 동의: Steel et al에 대한 대응Comment Published on 2020-12-012022-09-11 Journal: Journal of medical ethics [Category] SARS, 임상, [키워드] Autonomy clinical trials condition COVID-19 COVID-19 vaccine COVID-19 vaccines Effect Eyal form human infection ignorance Informed consent knowledge likelihood participant Participation question Research Research Ethics steel Trial trials Uncertainty [DOI] 10.1136/medethics-2020-106793 PMC 바로가기 [Article Type] Comment