A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain)SARS-CoV-2와 함께하는 1년: 바르셀로나 시(스페인 카탈로니아)에서 전체 게놈 시퀀싱을 통한 바이러스 계통 순환의 역학 개요Coronaviruses Published on 2022-01-042022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] age antigenic B.1.1 B.1.1.7 B.1.177 B.1.351 B.1.617.2 Barcelona Catalonia circulating circulation clinical setting Complete consensus sequence consensus sequences COVID-19 D614G mutation E484K epidemiological events Genetic genetic diversity genetic variability GISAID hospital Illumina immunological L452R Lineage lineages MiSeq Molecular epidemiology Multiple Mutation N-terminal domain P.1 pandemic predominant primary care protocol Randomly Receptor-binding domain respiratory respiratory sample S protein SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 virus selected sequenced Spain T478K the receptor-binding domain the S protein vaccination variants viruses was performed were used WGS while whole-genome sequencing [DOI] 10.1080/22221751.2021.2011617 PMC 바로가기 [Article Type] Coronaviruses
Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in JapanArticle Published on 2022-01-042022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome affected Analysis Atlantica Characteristics characterized Cluster coronavirus Costa Atlantica COVID-19 Cruise ship diamond Evolution Genetic Haplotype indicated information initial introduced Japan lockdown Mutation network analysis novel coronavirus disease P681H pandemic Phylogeny Princess provided reported resulting SARS-CoV-2 SARS-CoV-2 strain second Spread strain the spike protein Transmission unique virus Whole-genome sequence [DOI] 10.3390/microorganisms10010099 PMC 바로가기 [Article Type] Article
Spread of multiple SARS-CoV-2 lineages April-August 2020 anticipated the second pandemic wave in Lombardy (Italy)Article Published on 2022-01-012022-11-15 Journal: Pediatric allergy and immunology : official public [Category] SARS, 변종, 치료기술, [키워드] addition amino acid change anticipated B.1 B.1.1 circulation COVID-19 disease early phase Evolution FIVE investigated Italy Lineage lockdown lombardy majority molecular Molecular epidemiology NGS novel lineage occurred pandemic promoted Region reported Result SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 strain Sequencing Seven spike gene sequence Spread strain the disease the receptor-binding domain the spike protein Transmission variant variants of concern virus whole genome Whole genome sequencing [DOI] 10.1111/pai.13641 PMC 바로가기
Emergence of a novel SARS-CoV-2 Pango lineage B.1.1.526 in West Bengal, India인도 서벵골에서 새로운 SARS-CoV-2 Pango 계보 B.1.1.526의 출현Article Published on 2022-01-012022-09-11 Journal: Journal of infection and public health [Category] SARS, 변종, [키워드] Analysis B.1.1.526 Characteristics characterized circulating clade Cluster collected country COVID-19 D614G distribution domain E484K E484K mutation E484K mutations emergence Epidemiology Evolution favor genomic geographical distribution GISAID database higher infectivity immune India Interaction Invasion Kolkata Lineage MONITOR Mutation mutations P681H pandemic Phylogenetic analysis Phylogenetic tree reported resulting retrieved S glycoprotein S2 subunit SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 strain SARS-CoV-2 strains second wave sequence Sequence alignment Seven strain Strains Surveillance Temporal Temporal analysis transmembrane domain Transmissibility USA V1230L variant variant of SARS-CoV-2 variants viral envelope virion virus was performed West West Bengal. [DOI] 10.1016/j.jiph.2021.11.020 PMC 바로가기 [Article Type] Article
Animal Models of COVID-19: Transgenic Mouse ModelArticle Published on 2022-01-012022-11-15 Journal: Methods in molecular biology (Clifton, N.J.) [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome animal animal model Antiviral Brain C57BL/6 cause caused changes in concern coronavirus coronavirus disease COVID-19 COVID-19 disease cytokeratin 18 promoter death described ELISA enzyme-linked immunosorbent evaluated expressing global public health hACE2 hallmark Histopathology human Angiotensin-converting enzyme IHC immune response immunohistochemistry infected intranasally Infection K18 K18 hACE2 transgenic mice lung Lungs Model morbidity Mortality mouse mouse model nasal nervous system neutralizing monoclonal antibodies pathogenesis of SARS-CoV-2 pathogenicity pathology Prophylactic protocol respiratory tracts responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain spleen Spread survival the cytokine storm therapeutic tissues transgenic transgenic mice Treatment Vaccine viral pathogenesis viral replication virus Wuhan, China [DOI] 10.1007/978-1-0716-2111-0_16 PMC 바로가기
Evaluation of Three Quantitative Anti-SARS-CoV-2 Antibody Immunoassays3가지 정량적 항-SARS-CoV-2 항체 면역분석법의 평가Research Article Published on 2021-12-222022-09-10 Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술, [키워드] (Abbott Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antibody titer Antibody titers Antigen binding antibodies caused Chemiluminescent assay convalescent plasma coronavirus correlated correlation COVID Critical detect determine DiaSorin ELISA evaluated herd immunity house identify IgG Immunity immunization immunoassay Infection International international standard less LIAISON Live virus monoclonal antibodies Neutralization assay Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers NIBSC not correlated pandemic performed Postinfection proportional bias Protective respiratory SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 strain sensitivities sensitivity sera serological Serological assay serological assays serological result serological results severe acute respiratory syndrome Coronavirus significantly Specificities specificity spike tested the immunoassay the SARS-CoV-2 Treatment vaccination virus neutralization assay virus neutralization assays Virus spike WHO [DOI] 10.1128/spectrum.01376-21 PMC 바로가기 [Article Type] Research Article
Identification of the SARS-CoV-2 Delta variant C22995A using a high-resolution melting curve RT-FRET-PCR고해상도 용융 곡선 RT-FRET-PCR을 사용한 SARS-CoV-2 Delta 변이체 C22995A 식별Coronaviruses Published on 2021-12-212022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] C22995A mutation can be used country COVID-19 patient COVID-19 patients Delta delta variant Delta variants detect diagnose diagnostic diagnostic laboratories DNA effective FRET-PCR Genome sequencing High-resolution high-resolution melting curve analysis identification identify investigated Laboratory Melting point nasal swab percentage performed positive Prevalence reaction required RNA SARS-CoV-2 SARS-CoV-2 Delta variant SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 variants sequence Sequencing strain Strains the SARS-CoV-2 thermocycler time-consuming variant variants was performed [DOI] 10.1080/22221751.2021.2007738 PMC 바로가기 [Article Type] Coronaviruses
A rapid real-time polymerase chain reaction-based live virus microneutralization assay for detection of neutralizing antibodies against SARS-CoV-2 in blood/serumResearch Article Published on 2021-12-102022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 24 hours antibody antiviral activity blood/serum calculate can be used conducted COVID-19 case cross-reactive Culture Cytopathic effect Dilution dilutions dose evaluate IgG titer individual individuals infected cell infective limiting dilution Live virus lysed microneutralization nasopharyngeal specimen neutralization Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing assay PCR percentage polymerase chain positive positively correlated RBD recovering from COVID-19 responses Result RNA RT-PCR SARS-CoV-2 SARS-CoV-2 infected individuals SARS-CoV-2 microneutralization assay SARS-CoV-2 strain sera serum serum antibody serum samples shown spike structural proteins TCID50 tested the Spike tissue Vero cells viral neutralization virus-neutralizing was used were used [DOI] 10.1371/journal.pone.0259551 PMC 바로가기 [Article Type] Research Article
A Case Report: Genetically Distinct Severe Acute Respiratory Syndrome Coronavirus-2 Variant Causing ReinfectionMicrobiology Published on 2021-12-092022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute infection Analysis B.1.1.7 Bangladesh bilateral consolidation C-reactive protein causing clade collected continuous monitoring COVID-19 eight elevated ferritin Genetic variation Genome Immunity Infection International Intervention Lineage management mild symptoms monoclonal antibodies Mutation nasopharyngeal sample natural infection occurred outcome pangolin Patient PROTECT RBD Reinfection respiratory SARS-CoV-2 SARS-CoV-2 strain strain the patient the receptor-binding domain Treatment vaccination Vaccine variant variants variants of SARS-CoV-2 whole-genome sequencing Wuhan-Hu-1 [DOI] 10.3389/fmicb.2021.792514 PMC 바로가기 [Article Type] Microbiology
Identification and characterization of SARS-CoV-2 clusters in the EU/EEA in the first pandemic wave: additional elements to trace the route of the virus첫 번째 대유행 물결에서 EU/EEA의 SARS-CoV-2 클러스터 식별 및 특성화: 바이러스 경로를 추적하기 위한 추가 요소Article Published on 2021-12-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, [키워드] Analysis analyzed Area association circulating Cluster cluster analysis collected Complete confirmed COVID-19 case country COVID-19 dataset early phase element Europe European First wave Frequency identification Italian molecular analysis Mutation mutations nucleotide pandemic Phylogenetic analysis responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 strain single nucleotide SNV SNVs analysis. statistically significant the SARS-CoV-2 virus virus spread [DOI] 10.1016/j.meegid.2021.105108 PMC 바로가기 [Article Type] Article