Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered A single-center, retrospective, observational study중국 동북부 7개 도시에서 완전히 회복된 COVID-19 환자 55명에 대한 의료 치료 단일 센터, 후향적, 관찰 연구Observational Study Published on 2021-01-152022-09-10 Journal: Medicine [Category] 임상, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered administration Antibiotics antiviral drug antiviral drugs antiviral therapy benefit caused China Clinical outcome clinical outcomes Co-infection collected Controlled trial controlled trials coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demographics double-blind drug early administration effective emerging disease glucocorticoid Glucocorticoids immunomodulators Intervention Laboratory Linezolid Lopinavir Lopinavir/ritonavir lopinavir/ritonavir) median medical treatment medication Mild mild symptoms moxifloxacin observational study Patient patients with COVID-19 reduce respiratory retrospective risk Ritonavir SARS-CoV-2 Seven severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe group severe symptoms single-center Symptoms the disease transferred treat treated Treatment umifenovir [DOI] 10.1097/MD.0000000000023923 PMC 바로가기 [Article Type] Observational Study
Comparison of Liver Biomarkers in 288 COVID-19 Patients: A Mono-Centric Study in the Early Phase of PandemicMedicine Published on 2021-01-152022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] affecting age albumin ALP ALT Analysis AST baseline Chinese Clinical characteristics coronavirus disease correlation COVID-19 COVID-19 patient COVID-19 patients Critical Critical case demographic discharge disease disease severity enrolled exceeded Factor group hepatic dysfunction highest Hospitalization Hypoxemia indicated Intervention LDH liver biomarker liver biomarkers Liver function Liver injury Medicine novel coronavirus pneumonia occurred Patient patients phase prealbumin Prognosis proportion recent rising SARS-CoV-2 severe group severe hepatic dysfunction Severe patient stratified subtype Symptom temperature three groups Traditional Version [DOI] 10.3389/fmed.2020.584888 PMC 바로가기 [Article Type] Medicine
Clinical Symptom Differences Between Mild and Severe COVID-19 Patients in China: A Meta-Analysis중국의 경증 및 중증 COVID-19 환자 간의 임상 증상 차이: 메타 분석Meta-Analysis Published on 2021-01-142022-09-12 Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, [키워드] 95% confidence interval abdominal pain anorexia article Chest China Chinese clinical clinical feature Clinical features Clinical presentations clinical symptom CNKI confirmed case cough COVID-19 COVID-19 epidemic COVID-19 patient diarrhea difference differences disease deterioration distribution Dyspnea fatigue Fever headache hemoptysis identify initial initial symptom Meta-analysis Mild myalgia nausea novel Odds ratio Patient pharyngalgia potential risk prevalence of COVID-19 Prevent Prognosis Research retrieved risk factor searched selected Severe case severe group Severe patient severe patients statistically significant Trial two group vomiting Web of Science [DOI] 10.3389/fpubh.2020.561264 PMC 바로가기 [Article Type] Meta-Analysis
A novel deep learning-based quantification of serial chest computed tomography in Coronavirus Disease 2019 (COVID-19)코로나바이러스 질병 2019(COVID-19)에서 직렬 흉부 컴퓨터 단층 촬영의 새로운 딥 러닝 기반 정량화Article Published on 2021-01-112022-09-01 Journal: Scientific Reports [Category] 진단, [키워드] benefit calculated Chest computed tomography chest CT scan Chest CT scans Computed tomography Conventional correlation COVID-19 deep learning demonstrated disease severities disease severity estimation faster groups involved lesions moderate Patient performed predicted pulmonary involvement pulmonary lesion pulmonary lesions quantification reached semi-quantitative severe group Severe patient Spearman’s correlation symptom onset Translational research viral infection [DOI] 10.1038/s41598-020-80261-w PMC 바로가기 [Article Type] Article
The chronic kidney disease and acute kidney injury involvement in COVID-19 pandemic: A systematic review and meta-analysisCOVID-19 범유행에 대한 만성 신장 질환 및 급성 신장 손상 관련: 체계적인 검토 및 메타 분석Research Article Published on 2021-01-052022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, [키워드] Acute kidney injury AKI applied Blood urea nitrogen calculated China Chronic kidney disease CKD Complication Continuous renal replacement therapy COVID-19 COVID-19 pandemic COVID-19 patients creatinine Critical CRRT Effect elevated indicated involved kidney Kidney disease mean difference measurement Meta-analysis nitrogen occur Odds ratio Odds ratios outcome Patient renal replacement therapy replacement therapy reported Result review risk serum creatinine severe COVID-19 severe COVID-19 patient severe COVID-19 patients severe group severity of COVID-19 significantly increased SMD Spread susceptible systematic review the SARS-CoV-2 Trial urea [DOI] 10.1371/journal.pone.0244779 PMC 바로가기 [Article Type] Research Article
Features of α-HBDH in COVID-19 patients: A cohort studyCOVID-19 환자에서 α-HBDH의 특징: 코호트 연구Observational Study Published on 2021-01-012022-08-31 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, 바이오마커, 임상, [키워드] Accuracy age approach change Clinical features clinical manifestation cohort study Comorbidity coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 group COVID-19 patients Critical death death group demographics early stage electronic medical records excluded exclusion feature group groups heart hydroxybutyrate hydroxybutyrate dehydrogenase kidney Laboratory laboratory findings lack medical record medical records no significant difference organ other tissue outcome Patient present Prognosis Regression model respiratory respiratory infection risk of death severe group significant difference significant differences Spread survival group three group was increased [DOI] 10.1002/jcla.23690 PMC 바로가기 [Article Type] Observational Study
Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19인터루킨-18의 예후 가치와 코로나19의 다른 염증 표지자 및 질병 중증도와의 연관성Article Published on 2021-01-012022-09-11 Journal: Cytokine [Category] MERS, 바이오마커, [키워드] Admission age and sex analyzed antagonist antagonists approach association Asymptomatic biochemical marker biochemical markers blood sample Blood samples Care Characteristics Clinical characteristics clinical trial clinical trials collected Concentration consequence control group correlated COVID-19 COVID-19 pathogenesis COVID-19 patient COVID-19 patients creatinine CRP cut off value cytokine Cytokines D-dimer death defined demographic and clinical characteristics determined by detrimental Diagnosis died dimer disease disease severity ELISA enrolled Enrollment Evidence feature ferritin healthy subject healthy subjects highest hospital discharge ICU ICU admission IL-18 IL-6 immune response increased risk individual Inflammatory marker inflammatory markers intensive care intensive care unit interleukin Interleukin-18 Laboratory lead liver enzyme liver enzymes Macrophage macrophage activation syndrome male median age Mild mild pneumonia nine nucleic acid on admission organ organ injury outcome Patient Pneumonia procalcitonin Prognosis radiological required Result RT-PCR SARS-CoV-2 nucleic acid serum serum concentrations Serum level serum levels severe COVID-19 patients severe group severe pneumonia study population three group three groups Treatment troponin Viral viral infections were measured with COVID-19 [DOI] 10.1016/j.cyto.2020.155302 PMC 바로가기 [Article Type] Article
Cytokine profile and disease severity in patients with COVID-19COVID-19 환자의 사이토카인 프로필 및 질병 중증도Article Published on 2021-01-012022-09-11 Journal: Cytokine [Category] 바이오마커, [키워드] (enzyme-linked immunosorbent assay age All participants Analysis ANOVA both groups can be used collected Concentration conducted control group controls coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine dysregulation cytokine level cytokine levels Cytokines disease severity dysregulation ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate healthy subject IFN-γ IL-17 IL-5 IL-8 IL-9 in both group infected with SARS-CoV-2 interferon interferon-γ interleukin involved mechanism Mild not differ one-way ANOVA participant Patient patients patients with COVID-19 Predictive proinflammatory responses serum Serum level serum levels serum sample serum samples severe group severity significant difference significant differences significantly significantly higher statistical analysis systemic tested TGF-β Th1 Th17 Treg was performed [DOI] 10.1016/j.cyto.2020.155323 PMC 바로가기 [Article Type] Article
Early prediction and identification for severe patients during the pandemic of COVID-19: A severe COVID-19 risk model constructed by multivariate logistic regression analysisResearch Theme 1: COVID-19 Pandemic Published on 2020-12-042022-10-31 Journal: Journal of Global Health [Category] COVID-19, MERS, SARS, [키워드] age albumin Analysis caused Clinical characteristics Clinical data clinician Comorbidities Corona COVID-19 demonstrated duration of fever early stage elevated enrolled evaluate Factor force help hypertension identify illness onset independent Infectious disease Lymphocyte count lymphopenia mechanical ventilation Mild Mortality Most patient multivariate logistic regression Negative predictive value neutrophil lymphocyte ratio NLR oxygen pandemic Patient patients with COVID-19 Positive predictive value Predictive predictor proportion receiver operating characteristic reducing required respiratory symptoms Result retrospective risk ROC ROC Curve second Sensitivity and specificity severe COVID-19 severe group Severe patient severe patients therapeutic Treatment two groups university viral clearance was used were used worldwide pandemic [DOI] 10.7189/jogh.10.020510 PMC 바로가기 [Article Type] Research Theme 1: COVID-19 Pandemic
Comparing outcomes of hospitalized patients with moderate and severe COVID-19 following treatment with hydroxychloroquine plus atazanavir/ritonavir하이드록시클로로퀸 + 아타자나비르/리토나비르 치료 후 중등도 및 중증 COVID-19로 입원한 환자의 결과 비교Comparative Study Published on 2020-12-012022-09-11 Journal: Daru : journal of Faculty of Pharmacy, Tehran Univ [Category] 치료제, [키워드] 28-day mortality Admission adverse events age Antiviral antiviral therapy Atazanavir atazanavir/ritonavir baseline Clinical outcome clinical outcomes Complication Course COVID-19 Definition discharge discharge rate discharged patient discharged patients disease Dyspnea Efficacy and safety evaluated exertional dyspnea Hair loss hospital Hospital admission hospital discharge Hospital stay Hospitalization hospitalized patient Hydroxychloroquine ICU incidence intensive care intensive care unit intubation investigated Length less male matter moderate Mortality National national treatment outcome outcomes oxygen Patient patients patients treated patients with COVID-19 patients with moderate peripheral oxygen saturation Pneumonia regimen Ritonavir Serious Adverse Event Serious Adverse Events severe COVID-19 severe disease severe group severity significantly higher significantly shorter SpO2 Support Symptom the disease the patient Treatment treatment of COVID-19 Treatment protocol use of hydroxychloroquine weakness WHO definition [DOI] 10.1007/s40199-020-00369-2 PMC 바로가기 [Article Type] Comparative Study