TLR

[키워드] “cytokine storm” ACE2 activating Activation Affect affecting alveolar epithelial cells angiotensin-converting enzyme 2 Anti-viral Cathepsins caused cellular entry cellular receptors cellular signaling pathway Community coronavirus CoV COVID-19 Deleterious dendritic cell downregulating downregulation DPP4 Epidemics event Exacerbation Factor furin glycoprotein H1N1 Haemagglutinin Health Host IL-8 infected patients Inflammation initial initial viral load Innate innate immune response innate immune responses involved Ligand ligands Like lung lung innate immunity Macrophage middle multiple organ failure outbreak pandemic Pandemics pro-inflammatory mediator promoted protease Proteases Protein Resolution respiratory RNA genome SARS-CoV SARS-CoV-2 serine 2 single-stranded survival syndrome T-cell TLR TMPRSS2 transmembrane serine protease triggering trimeric spike TTSP type I type III virus virus entry
[DOI] 10.3389/fimmu.2020.01229 PMC 바로가기 [Article Type] Immunology