Detection of SARS-CoV-2 within the healthcare environment: a multi-centre study conducted during the first wave of the COVID-19 outbreak in England의료 환경 내 SARS-CoV-2 검출: 영국에서 COVID-19 발생의 첫 번째 물결 동안 수행된 다기관 연구Multicenter Study Published on 2021-02-012022-09-11 Journal: The Journal of hospital infection [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 aerosol air analysed assays Bacterial Chain Reaction cleaning Concentration Concomitant conducted Contact coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 outbreak cycle Cycle threshold values detection dispersal effective eight England environmental contamination Environmental surfaces facilitate First wave genomic Guidance healthcare hospital hospitalized patients infection control Infectious virus investigated Measures nosocomial Nosocomial transmission not recovered outbreak patients PCR PCR-positive performed persistence Personal protective equipment polymerase chain polymerase chain reaction Prevent PROTECT ranged reduce respiratory respiratory symptoms reverse transcription reverse transcription polymerase chain reaction risk Sample SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus Spread Support survival threshold value Transmission understanding undetectable Viral Viral RNA virus virus isolation [DOI] 10.1016/j.jhin.2020.11.024 PMC 바로가기 [Article Type] Multicenter Study
Application of deep learning techniques for detection of COVID-19 cases using chest X-ray images: A comprehensive studyResearch article Published on 2021-02-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 치료기술, [키워드] Accuracy Algorithm Analysis application artificial automated caused chain chest X-ray Chest X-ray image CNN confirmed case Convolutional neural networks COVID-19 COVID-19 case COVID-19 infection deep deep learning Diagnosis early diagnosis effective Effectiveness eight evaluate Factor FIVE globe greatly reduce Health hospital intelligence learning network Neural Optimization algorithms reaction researcher RT-PCR SARS-CoV-2 time-consuming virus X-ray [DOI] 10.1016/j.bspc.2020.102365 [Article Type] Research article
Analytical and clinical validation of an ELISA for specific SARS-CoV-2 IgG, IgA, and IgM antibodies특정 SARS-CoV-2 IgG, IgA 및 IgM 항체에 대한 ELISA의 분석 및 임상 검증Comparative Study Published on 2021-02-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis antibodies antibody Bio-rad Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19, ELISA cut-off cut-offs eight ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay external validation IgA IgG IgM IgM antibody immunoassay Immunoglobulin immunoglobulin A Immunoglobulin G immunoglobulin M Kinetics nucleocapsid Patient positive Quantitative reaction Receiver operator characteristic respiratory RT-qPCR SARS-CoV-2 SARS-CoV-2 IgG sensitivity sensitivity analysis Sensitivity and specificity sera serological test Serological tests severe acute respiratory syndrome Coronavirus specificity Total total antibodies total antibody virus were used [DOI] 10.1002/jmv.26303 PMC 바로가기 [Article Type] Comparative Study
Reporting and design of randomized controlled trials for COVID-19: A systematic reviewCOVID-19에 대한 무작위 대조 시험의 보고 및 설계: 체계적인 검토Article Published on 2021-02-012022-09-11 Journal: Contemporary clinical trials [Category] SARS, 임상, [키워드] clinical trials conducted coronavirus COVID-19 COVID-19 RCT COVID-19 RCTs eight greater Guidance highlight hospital identify Intervention limitation literature review location majority median methodological novel Novel coronavirus novel coronavirus 2019 outcomes pandemic participant Patient peer-reviewed Randomized controlled trial Randomized controlled trials RCTs recruitment Registered registry reported Reporting Research robust Study design systematic literature review systematic review targets Trial trials while [DOI] 10.1016/j.cct.2020.106239 PMC 바로가기 [Article Type] Article
Predicting severe or critical symptoms in hospitalized patients with COVID-19 from Yichang, China중국 이창에서 코로나19로 입원한 환자의 중증 또는 중대 증상 예측Research Paper Published on 2021-01-312022-08-31 Journal: Aging (Albany NY) [Category] MERS, SARS, 바이오마커, [키워드] 95% CI 95% confidence interval Accuracy albumin blood cell C-index China Committee coronavirus disease Coronavirus disease 2019 correlations COVID-19 COVID-19 diagnosis Critical diagnosed diagnostic eight enrolled estimate Evidence Factor Factors FIVE Health Committee hospitalized patient identify independent Lactate lactate dehydrogenase Mild neutrophil nomogram Odds ratio Patient patients with COVID-19 potential risk prediction propensity score matching released retained risk severe or critical symptoms significantly statistical adjustment Symptom Treatment White blood cell with COVID-19 [DOI] 10.18632/aging.202261 PMC 바로가기 [Article Type] Research Paper
Mesenchymal stem cells derived from perinatal tissues for treatment of critically ill COVID-19-induced ARDS patients: a case seriesCOVID-19로 유발된 중증 ARDS 환자 치료를 위한 주산기 조직 유래 중간엽 줄기세포: 사례 시리즈Clinical Trial Published on 2021-01-292022-08-13 Journal: Stem Cell Research & Therapy [Category] 바이오마커, 임상, 진단, [키워드] acute renal and hepatic failure acute respiratory distress syndrome age Allogeneic allogeneic prenatal Alpha ARDS ARDS patients C-reactive protein C-reactive protein (CRP candidate Cardiac arrest Cardiomyopathy case sery cell infusion cell infusions Cell therapy cells chronic lymphocytic leukemia clinical trial CLL CMP Comorbidities Comorbidity Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill develop diabetes diagnosed died discharged distress Dyspnea eight enrolled fatal complication feasibility finding FIVE hepatic failure High dose hospital human umbilical cord MSCs hypertension Hypoxemia ICU ICUs IFN-γ IL-6 IL-6 level IL-6 levels IL-8 IMPROVE Inflammatory biomarker inflammatory biomarkers infusion intensive care unit intensive care units interferon gamma intravenous infusion Large randomized multicenter clinical trials leukemia Leukocytosis lung lymphocyte Lymphocytes mechanical ventilation men mesenchymal stem cell Mesenchymal stem cells Mesenchymal stromal cells MSC MSCs multi-organ failure multicenter one patient outcome Patient patients perinatal tissue Phase 1 PL-MSCs Placenta placental MSC placental MSCs Pneumonia Potential treatment Radiological parameter Radiological parameters Randomized reduce reduced renal reported required respiratory distress Respiratory distress syndrome Safe Sepsis Serious Adverse Event Serious Adverse Events Serum level serum levels Seven severe hypoxemia Significant reduction significant reductions SpO2 stem cell Stem cell therapy supplementary material survivor Survivors syndrome the cell therapeutic potential TNF-α Tolerability Treatment Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-alpha UC-MSCs umbilical Umbilical cord women [DOI] 10.1186/s13287-021-02165-4 PMC 바로가기 [Article Type] Clinical Trial
Tracking the time course of pathological patterns of lung injury in severe COVID-19Research Published on 2021-01-292022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] activated age alveolar analysed Analysis ARDS Autopsy biopsies bronchopneumonia Characteristics characterized clinical picture correlated Course COVID COVID-19 COVID-19 patient DAD death died Diffuse alveolar damage disease Disease progression dysregulated eight Elderly patient Evolution Factors H&E Hospital admission Infarction invasive less lung cell Lung injury Lung pathology lung tissue Minimally Invasive Autopsy modulated occur parameters pathologist pathway Patient patients prevalent proportion pulmonary pulmonary involvement pulmonary microthrombosis pulmonary thrombosis Region respiratory Result SARS-CoV-2 severe COVID-19 severe COVID-19 patient submitted the disease the patient thrombosis variable Vascular vascular lesion [DOI] 10.1186/s12931-021-01628-9 PMC 바로가기 [Article Type] Research
A systematic review and realist synthesis on toilet paper hoarding: COVID or not COVID, that is the questionPsychiatry and Psychology Published on 2021-01-292022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] Asian association Case report clinical study cognitive biase cognitive biases conducted Contagion coronavirus coronavirus disease COVID COVID-19 COVID-19 pandemic criteria Cultural database diarrhoea Effect eight explain Factor Factors General population hoarding human population illnesses increase in involved Japan measure mechanism mechanisms Mental mental health problems objective Other outcome pandemic Patient Personality potential mechanism PsycINFO question Region Registration Result risk risk factor searched secondary outcome Singapore social media Stress Study design suggested systematic review Taiwan Toilet paper traits Web of Science [DOI] 10.7717/peerj.10771 PMC 바로가기 [Article Type] Psychiatry and Psychology
Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumorsSARS-CoV-2 감염에 대한 숙주 전사 반응의 메타 분석은 인간 종양에서의 발현을 나타냅니다Meta-Analysis Published on 2021-01-282022-09-01 Journal: Scientific Reports [Category] 유전자 메커니즘, 진단, [키워드] A549 activated adenocarcinoma bronchial epithelial cell Calu Calu-3 Cancer cancer cell Cancer cells Cell cell line cell line data common Data integration defined eight epithelial cells Gene regulatory networks histopathological Host immune response host response host responses Host transcriptional response IL-6 immune Immune cell infiltration immune response immune responses implicated Infection Inflammation interferon signaling lung adenocarcinoma lung cancer manifested model system Molecular biology NF-κB NHBE pathway Pathways Patient reveal SARS-CoV-2 SARS-COV-2 infection similarity subset the cell the SARS-CoV-2 Therapeutic strategies therapeutic strategy transcriptional transcriptomic Tumor Tumour immunology type II interferon Viral viral infection viral infections virus viruses [DOI] 10.1038/s41598-021-82221-4 PMC 바로가기 [Article Type] Meta-Analysis
Learning in peer teaching of patient relations and communication skills at the “Anamnesegruppen” Munich – proof-of-concept and lessons learnedArticle Published on 2021-01-282022-11-01 Journal: GMS Journal for Medical Education [Category] Coronavirus, [키워드] adaptation addition anamnesis groups Balint conducted confidentiality Corona Course COVID-19 digital teaching e-learning eight element evaluated feasibility Final four group group groups independent learning medical history Munich no significant difference not differ organized pandemic participant Patient patient interview peer-teaching positive preserved question recruited relationship medicine Research Stress student student teaching switching the patient [DOI] 10.3205/zma001400 PMC 바로가기 [Article Type] Article