The Folate Concentration and/or Folic Acid Metabolites in Plasma as Factor for COVID-19 InfectionPharmacology Published on 2020-07-162022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 3CL pro ACE2 acid age block Care COVID-19 COVID-19 pandemic COVID-19 patient Department explained Factor folate Folic acid furin furin protease H1N1 pandemic Hospitalized host cell independent Infection Infectious disease Influenza inhibit less mechanism outbreak Patient Pregnancy pregnant women Probability protease Protein Public reduced replicate Replication reported reproductive SARS-CoV-2 SARS-COV-2 infection susceptible viral infection virus women [DOI] 10.3389/fphar.2020.01062 PMC 바로가기 [Article Type] Pharmacology
The bright and dark sides of protein conformational switches and the unifying forces of infections단백질 구조 전환의 밝은 면과 어두운 면과 감염의 통합력Review Published on 2020-07-152022-09-10 Journal: Communications Biology [Category] SARS, 신약개발, 치료제, [키워드] Alter Bacterial bacterial toxins cellular entry Combination conformation conformational derived proteins domain functions glycoprotein Host identify Infection infections membrane molecular pathogen Pathogenesis Pathogens Perspective Protein Protein sequence analyses Proteins sequence sequences similarity spike glycoprotein Spike protein structural biology switching the Spike toxins virus viruses [DOI] 10.1038/s42003-020-1115-x PMC 바로가기 [Article Type] Review
Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral InfectionsPerspective Published on 2020-07-152022-11-01 Journal: Med (New York, N.Y.) [Category] COVID-19, MERS, SARS, [키워드] β-hydroxybutyrate activity acute respiratory syndrome Affect Body Cardiopulmonary cardiovascular disease cellular cognitive complications countermeasure COVID-19 Cytokine storm death Diabetes Mellitus Diseases ENhance exogenous ketone facilitate functional immune IMPROVE infecting Influenza influenza A influenza A virus Intervention ketone ketone bodies ketone body ketone ester ketone salt ketones killing maintain metabolism metabolite Pandemics pleiotropic effect Population reduce Research Resilience respiratory respiratory viral infection risk risk factor SARS-CoV-2 Seasonal influenza severe disease Signaling supportive care therapy viral infection virus [DOI] 10.1016/j.medj.2020.06.008 PMC 바로가기 [Article Type] Perspective
SARS-CoV-2/COVID-19: a primer for cardiologistsReview Article Published on 2020-07-152022-10-30 Journal: Netherlands Heart Journal [Category] COVID-19, [키워드] acute respiratory distress syndrome acute respiratory syndrome addition Antibody detection antiviral drug antiviral drugs approach caused complications coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 described develop disease feature health emergency immunological Immunomodulatory agent knowledge manifestation mild symptoms Most patient pandemic Perspective raise Research SARS-CoV-2 SARS-CoV‑2 SARS-CoV‑2 infection serological test severe acute respiratory syndrome coronavirus 2 severity Spread supplementary material Transmission treating COVID-19 Vaccine virological assay virus while Wuhan, China zoonotic [DOI] 10.1007/s12471-020-01475-1 PMC 바로가기 [Article Type] Review Article
Multisystem Inflammatory Syndrome With Complete Kawasaki Disease Features Associated With SARS-CoV-2 Infection in a Young Adult. A Case ReportMedicine Published on 2020-07-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] absence acute respiratory distress affected Anosmia Case report children Colchicine combined treatment Complete complications of COVID-19 coronary aneurysm COVID-19 COVID-19 infection Diagnosis feature hemodynamic instability High dose immune immune response immunoglobulins infection with SARS-CoV-2 Inflammatory inflammatory process Kawasaki disease limit manifestation Methylprednisolone MIS-C myocarditis Patient report reported SARS-CoV-2 serology specific antibody suggested syndrome Tocilizumab virus with COVID-19 [DOI] 10.3389/fmed.2020.00428 PMC 바로가기 [Article Type] Medicine
Therapeutic Strategies Against COVID-19 and Structural Characterization of SARS-CoV-2: A ReviewMicrobiology Published on 2020-07-142022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 2019-nCoV addition Against Antiviral antiviral agent Antiviral agents approved cellular characterization China Combination confirmed case coronavirus disease COVID-19 crystal structure death develop drug design Drug repurposing Ebola virus effective Efficacy HIV Host IMPROVE Novel coronavirus patients with COVID-19 public health reported Repurposed drug review SARS-CoV-2 Strategy target therapeutic Therapeutic strategies therapeutic strategy Treatment virus with COVID-19 Wuhan [DOI] 10.3389/fmicb.2020.01723 PMC 바로가기 [Article Type] Microbiology
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development530 Published on 2020-07-142022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition animal model antiviral drugs Characteristics China consequence consolidation convalescent serum coronavirus coronavirus disease countermeasure COVID-19 patient disease feature Ground glass opacity hamster hamsters Health human lung immunotherapies Infection inhibited intranasal isolate lesion lung lung lesion Lungs mounted naïve Neutralizing antibody response Novel coronavirus pathogenesis of SARS-CoV-2 Pneumonia Postinfection Region replicate replicated Replication replicative reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 isolate SARS-CoV-2 pathogenesis serum severe lung injury Significance Spread subsequent suppressed Syrian hamsters transfer Vaccine Vaccines virus virus replication Wuhan, China [DOI] 10.1073/pnas.2009799117 PMC 바로가기 [Article Type] 530
Correcting misperceptions of exponential coronavirus growth increases support for social distancing530 Published on 2020-07-142022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] Coronavirus, SARS, [키워드] comparison conducted coronavirus coronavirus disease Correcting COVID-19 effective exponential growth bias growth identify increase lack linear measure Measures pandemic Pandemics participant Prevent recruit Research Significance significantly social distancing Spread statistical statistical literacy Support the United State Vaccine virus [DOI] 10.1073/pnas.2006048117 PMC 바로가기 [Article Type] 530
Disease Outbreak Surge Response: How a Singapore Tertiary Hospital Converted a Multi-story Carpark Into a Flu Screening Area to Respond to the COVID-19 Pandemic질병 발생 급증 대응: 싱가포르 3차 병원이 COVID-19 전염병에 대응하기 위해 다층 주차장을 독감 검사 구역으로 전환한 방법Concepts in Disaster Medicine Published on 2020-07-142022-09-12 Journal: Disaster Medicine and Public Health Preparedness [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome affected Area caused contributed coronavirus Coronavirus disease 2019 COVID-19 COVID-19 disease death defined disaster disease element emergency medicine Emerging infectious diseases expand flu healthcare healthcare services hospital increase in Increased infectious disease outbreak numbers of patient outbreak Patient care Public public health emergency respond SARS-CoV-2 Screening seeking Singapore surge capacity Tertiary virus WHO World Health Organization [DOI] 10.1017/dmp.2020.249 PMC 바로가기 [Article Type] Concepts in Disaster Medicine
Aerosol and environmental surface monitoring for SARS-CoV-2 RNA in a designated hospital for severe COVID-19 patientsOriginal Paper Published on 2020-07-142022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aerosol collected Concentration concerning Contamination coronavirus Cross-infection effective Effectiveness eliminating environmental surface examined hospital hospitals implementation indicated Infection prevention information microbial Patient positive reducing risk SARS-CoV-2 SARS-CoV-2 RNA severe COVID-19 patient severe COVID-19 patients Swab swabs Viral load virus [DOI] 10.1017/S0950268820001570 PMC 바로가기 [Article Type] Original Paper