Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains UnclearArticle Published on 2020-07-032022-10-05 Journal: Cell [Category] SARS, 변종, [키워드] change COVID-19 D614G disease dominant in vitro data Making Mutation phenotype SARS-CoV-2 variant sense the spike protein therapeutic Transmission Vaccine virus [DOI] 10.1016/j.cell.2020.06.040 [Article Type] Article
SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle EastResearch Article Published on 2020-07-032022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition Americas clade clades contributed coronavirus COVID-19 Culture dominant Europe First wave Frame Genome sequencing Genomic surveillance genomic variation Infection Iran Local Middle East mutant Mutation ORF8 ORF8 deletion Patient performed Phylogenetic analysis Phylogeny SARS-CoV-2 SARS-CoV-2 genomic surveillance SARS-CoV-2 strain SARS-CoV-2 transmission second wave sequenced Sequencing strain Strains Taiwan trajectory Transmission Travel Turkey virus Wuhan [DOI] 10.1080/22221751.2020.1782271 PMC 바로가기 [Article Type] Research Article
A Perspective on Emerging Therapeutic Interventions for COVID-19COVID-19에 대한 새로운 치료 개입에 대한 관점Review Published on 2020-07-032022-09-11 Journal: Frontiers in Public Health [Category] MERS, 유전자 메커니즘, 치료제, [키워드] approach approved characterized clinical study Compound Control COVID-19 COVID-19 pandemic disease Health Infection lack management medication Novel coronavirus outbreak pathogenicity positive-sense positive-sense RNA viruses public health replication mechanism RNA genome RNA virus SARS-CoV-2 spike Spread Therapeutics Treatment Treatment strategies treatments for COVID-19 unique Vaccines Viral viral replication virus viruses [DOI] 10.3389/fpubh.2020.00281 PMC 바로가기 [Article Type] Review
Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the ScienceReview Published on 2020-07-022022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome Case fatality rate CFR common cold coronavirus coronavirus 2 cross disease Epidemiology highest Human infecting Intervention knowledge MERS-CoV Middle East outbreak pandemic Prophylactic respiratory resulting SARS-CoV SARS-CoV-2 Science scored state therapeutic Transmission virus zoonotic zoonotic disease [DOI] 10.3390/microorganisms8070991 PMC 바로가기 [Article Type] Review
Beyond Anti-viral Effects of Chloroquine/HydroxychloroquineImmunology Published on 2020-07-022022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] ACE2 affected anti-inflammatory property anti-viral effect antigen processing Antiviral appear Arthritis Autoimmune diseases autophagy cellular activation Chloroquine country COVID-19 COVID-19 pandemic COVID-19 patients cytosolic decrease detrimental discrepancy Effect Efficacy explain highlight Host immune response Hydroxychloroquine in vitro Inflammation Inflammatory cytokine inflammatory process inhibit interfere interferon limit lysosomal nucleic acids Patient progression receptor remained Replication required RIG-I SARS virus SARS-CoV2 SARS-CoV2 infection secretion Signaling STING therapy TLR Toll-like receptor Treatment type I interferon virus [DOI] 10.3389/fimmu.2020.01409 PMC 바로가기 [Article Type] Immunology
Infection Control in Dental Practice During the COVID-19 PandemicArticle Published on 2020-07-022022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected Blood body fluid cause Characteristics China Clinical practice close contact Contagion Control Coronavirus infection cough COVID-19 dental dental practitioner dentist dentistry example generate guidelines hand hygiene high risk Infection infection in dentistry occur Organisms pathophysiological Patient Pneumonia Practice prevention procedures preventive dentistry reducing Respiratory droplets risk Saliva SARS virus SARS-CoV-2 SARS-COV-2 infection sneeze Spread supported surgical symptomatic people syndrome the disease the epidemic transmissibility of SARS-CoV-2 Transmission virus [DOI] 10.3390/ijerph17134769 PMC 바로가기 [Article Type] Article
Clinical characteristics of four cancer patients with SARS-CoV-2 infection in Wuhan, ChinaCase Report Published on 2020-07-022022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] acute respiratory syndrome advanced age B cell B cells Bacteria Cancer cancer patient Cancer patients CD3 Characteristics Chemotherapy clinical clinical feature combination therapy contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-2019 dead decrease diagnosed fungi hepatitis B Hepatocellular carcinoma hospital immune system immunosuppressive Infection leukemia Liver transplantation lymphocyte Mild natural killer cell outbreak Patient Pneumonia Radiotherapy Respiratory Support SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 severity of COVID-19 suffered survived susceptible T cells therapy Treatment tumors underlying disease underlying diseases viral infection virus were infected Wuhan Wuhan, China [DOI] 10.1186/s40249-020-00707-1 PMC 바로가기 [Article Type] Case Report
An approach to teaching psychiatry to medical students in the time of Covid-19Perspective Piece Published on 2020-07-022022-10-30 Journal: Irish Journal of Psychological Medicine [Category] Coronavirus, SARS, [키워드] approach change changed clinical care clinician college COVID-19 effort facilitate Health healthcare Healthcare systems injected medical education Medical Science Medicine online teaching psychiatry reduce required School social distancing Spread student engagement university virus [DOI] 10.1017/ipm.2020.87 PMC 바로가기 [Article Type] Perspective Piece
Estimation of country-level basic reproductive ratios for novel Coronavirus (SARS-CoV-2/COVID-19) using synthetic contact matricesResearch Article Published on 2020-07-022022-10-28 Journal: PLoS Computational Biology [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus age America Asia assumed Asymptomatic Asymptomatic case Atypical calculate caused children China Clinical symptoms comparable complex Contact country COVID-19 COVID-19 transmission dependent on driven by epidemiological data estimate estimation Europe Frequency generate groups heterogeneity highest individual infect Infection intensity Intensive Japan laboratory-confirmed lowest mathematical measure Mild null model Older Older age outbreak over pandemic pathogen pathogen’ Pneumonia populations predict predicted Probability reported reproductive reversed SARS-CoV-2 Spread spread of COVID-19 Structure susceptibility Symptom the disease Transmission Transmission model virus [DOI] 10.1371/journal.pcbi.1008031 PMC 바로가기 [Article Type] Research Article
A candidate multi-epitope vaccine against SARS-CoV-2Article Published on 2020-07-022022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Analysis antigenic Biochemistry candidate vaccine caused codon optimization Computational biology and bioinformatics coronavirus determinants docking study Dynamics E. coli effective Efficiency expression Fatality rate host cell immune response Immune simulation immunology in silico In silico cloning induce Interaction MERS-CoV MHC Multi-epitope vaccine outbreak pandemic SARS-CoV SARS-CoV-2 Simulation spike glycoprotein stability supported the vaccine Vaccine vaccine candidate virus [DOI] 10.1038/s41598-020-67749-1 PMC 바로가기 [Article Type] Article