Early Phase of the COVID-19 Outbreak in Hungary and Post-Lockdown ScenariosArticle Published on 2020-06-302022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Case fatality rate compartmental model Contact COVID-19 COVID-19 epidemic COVID-19 outbreak disease early phase effective Effects Epidemic epidemiological Factors growth heterogeneity Hungary incidence of COVID-19 Intervention measure Measures phase reducing reduction in Reproduction number SARS-CoV-2 scenario statistical analysis suppressed Transmission under-ascertainment virus [DOI] 10.3390/v12070708 PMC 바로가기 [Article Type] Article
The changing pattern of COVID-19 in Nepal: A Global concern- A Narrative ReviewReview Article Published on 2020-06-302022-10-30 Journal: Nepal Journal of Epidemiology [Category] COVID-19, [키워드] accounted age Cohort conducted confirmed case coronavirus COVID-19 COVID-19 infections deaths develop English event female Google Scholar International investigated Laboratory male Ministry of Health Mortality narrative Nepal Patient recorded reported review risk SARS-CoV-2 situation the mean virus WHO Youth [DOI] 10.3126/nje.v10i2.29769 PMC 바로가기 [Article Type] Review Article
Predicted peptide patterns from the SARS-CoV-2 proteome for MS-MS based diagnosisResearch Article Published on 2020-06-302022-10-28 Journal: Bioinformation [Category] COVID-19, [키워드] 2019 novel coronavirus Analysis biological fluid body fluid can be used caused complex COVID-19 dataset Diagnosis early diagnosis Health manifested nasopharyngeal swabs pandemic PCR peptide platform proteome SARS-CoV-2 SARS-CoV-2 peptides SARS-CoV-2 viral Skyline targeted proteomics the SARS-CoV-2 the WHO tryptic peptides Variability viral mutation virus [DOI] 10.6026/97320630016477 PMC 바로가기 [Article Type] Research Article
Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory responseResearch Paper Published on 2020-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] age Analysis caused cellular change chromosome segregation consequence Coronavirus disease 2019 COVID-19 COVID-19 patient Critical develop Health host cell human cells in vitro inflammatory reaction Inflammatory response investigated Lung injury mitosis network analysis outbreak pathway Pathway analysis Protein proteome proteomics proteomics data SARS-CoV-2 SARS-COV-2 infection severity Stage Symptom Treatment viral infection virus Wuhan, China [DOI] 10.18632/aging.103524 PMC 바로가기 [Article Type] Research Paper
SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?Review Published on 2020-06-302022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] ACE2 acute respiratory infections acute respiratory syndrome age association cardiovascular disease co-morbidity complications connection coronavirus coronavirus disease COVID-19 COVID-19 patient diabete diabetes Diabetes mellitus (DM) diabetic patient diabetic patients driving epidemiological data Factor Glucose homeostasis Infection MERS outcome pandemic patients reported respiratory infections responsible SARS-CoV-2 SARS-CoV-2 disease severity susceptible therapeutic Treatment virus Wuhan, China [DOI] 10.1186/s12979-020-00192-y PMC 바로가기 [Article Type] Review
Identifying airborne transmission as the dominant route for the spread of COVID-19530 Published on 2020-06-302022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, [키워드] adopted aerosol Analysis Contact tracing coronavirus disease COVID-19 COVID-19 pandemic dominant effective Effectiveness Face mask highlight identifying Impact infections Intervention Italy measure Measures New York City Other pandemic Pandemics Prevent Protective public health quarantine reduce reduced remains uncertain reveal Significance significantly social distancing Spread spread of COVID-19 the disease The United States Transmission transmission pathway virulent virus virus transmission Wuhan, China [DOI] 10.1073/pnas.2009637117 PMC 바로가기 [Article Type] 530
Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral InfectionsReview Published on 2020-06-302022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] addition anti-vimentin autoantibodies antibody antiviral strategy appear approach autoantigen Autoimmune disease Bacterial Cell cell activation cell surface cell surface vimentin cell types cellular processe cellular receptor complex contribute coronavirus cytoplasmic cytoskeletal Encephalitis Extracellular filament protein functions immune response implication in viral Infection Inflammation Injury Interaction interfere intermediate filaments Migration modulate Occurrence oxidative damage Pathogens pathophysiological pathophysiology Perspective Phosphorylation posttranslational modifications Potential Proinflammatory cytokine Protein receptor required SARS-CoV secreted shown target tissue damage tissue damage and repair vimentin vimentin–pathogen interactions viral pathogenesis viral pathogens virus viruses [DOI] 10.3390/ijms21134675 PMC 바로가기 [Article Type] Review
De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2Research Paper Published on 2020-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, [키워드] ACE2 Analysis angiotensin-converting enzyme 2 antiviral drug antiviral therapeutic approach association binding binding affinity can be used COVID-19 COVID-19 disease Critical effective exhibited experiment global pandemic glycine hACE2 hACE2 protein human ACE2 human cell human cells impacted inhibit initiate interactions linker motif outbreak peptide peptides Protein protocol RBD receptor Receptor binding domain SARS-CoV-2 sequence significantly Spike protein stability the SARS-CoV-2 treat virus wild-type wild-type hACE2 [DOI] 10.18632/aging.103416 PMC 바로가기 [Article Type] Research Paper
Evidence for SARS-CoV-2 Infection of Animal HostsReview Published on 2020-06-302022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] animal animal modeling Antiviral bat bats caused conducted Coronaviridae coronavirus COVID-19 COVID-19 pandemic evaluated Evidence experimental models family Coronaviridae fatal infection ferrets group hamsters Host Human humans Infection interspecies transmission involved MERS-CoV pandemic pangolins pets reported Research reservoirs SARS-CoV SARS-CoV-2 shown susceptible sustained transgenic mice Transmission transmission of SARS-CoV-2 viral zoonosis virus zoo animals zoonotic [DOI] 10.3390/pathogens9070529 PMC 바로가기 [Article Type] Review
Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human HostPhysiology Published on 2020-06-302022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] Activation cardiovascular disease COVID-19 diabete dissect FIVE functional Host host mechanism host protein hub protein Human human lung hypertension in viral independent Infection initial lung mechanism MERS miRNA targets miRNAs MOST Pathogenesis Protein receptor Receptor binding regulated Replication risk SARS-CoV-2 SARS-COV-2 infection Seven Severity of infection Signaling Systems biology Transcriptome viral infection viral replication virus [DOI] 10.3389/fphys.2020.00802 PMC 바로가기 [Article Type] Physiology