Safety of COVID-19 Vaccine in Patients with Cancer in a High-Volume Comprehensive Cancer CenterBrief Communications Published on 2022-02-112022-10-28 Journal: The oncologist [Category] COVID-19, MERS, [키워드] 48 hours Administered ADR ADRS Adverse Adverse drug reaction adverse event anti-cancer treatment anti-SARS-CoV-2 BNT162b2 Cancer Cancer center cancer patient Cancer patients case sery center Chemotherapy Cohort Comprehensive COVID-19 COVID-19 vaccine Efficacy and safety event Italian malignancy mRNA National outcome Patient patients treated Patients with cancer Pfizer-BioNTech platform reported resolved Result retrieved Safety solid tumor Treatment Vaccine [DOI] 10.1093/oncolo/oyab037 PMC 바로가기 [Article Type] Brief Communications
Genophenotypic Factors and Pharmacogenomics in Adverse Drug ReactionsReview Published on 2021-12-102022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] administration ADR ADRS Adverse Adverse drug reaction Adverse drug reactions age benefit Biomarker Brain Cancer cardiovascular disease Cardiovascular disorders cause central nervous system disorders clinical setting COVID-19 cutaneous ADRs death disorders drug Drug efficacy Drug–drug interactions effective Factor feature genomic Genotype Health implementation involved lack limitation Major Microarray NGS organizations pathology pharmacogenomics physician problem Prospective Study provide reaction Regulation Sex Standardization Toxicity Vaccination strategies with COVID-19 [DOI] 10.3390/ijms222413302 PMC 바로가기 [Article Type] Review
Comparison of adverse drug reactions among four COVID-19 vaccines in Europe using the EudraVigilance database: Thrombosis at unusual sitesObservational Study Published on 2021-10-012022-10-05 Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval adenoviral vector vaccine ADR Adverse drug reaction Analysis AstraZeneca cerebral vein thrombosis collected COVID-19 COVID-19 vaccinations COVID-19 vaccine database Europe European Medicines Agency expressed first dose greater highest incidence janssen lowest Moderna occurred raised released reported thrombocytopenia thrombosis thrombotic Vaccine Vaccines was performed [DOI] 10.1111/jth.15493 PMC 바로가기 [Article Type] Observational Study
Impact of the COVID-19 outbreak on the reporting of adverse drug reactions associated with self-medicationResearch article Published on 2021-09-012022-10-05 Journal: Annales pharmaceutiques françaises [Category] 치료제, [키워드] ADR ADRS Adverse drug reaction affected analyzed ATC Characteristics children consequence COVID-19 COVID-19 outbreak Descriptive statistics disorders drugs effective First wave French Impact information mandatory material median age medication nervous system Non-COVID-19 objective pandemic Patient pharmacovigilance proportion recorded reported Result Self-medication were used [DOI] 10.1016/j.pharma.2021.02.003 [Article Type] Research article
Remdesivir in the COVID-19 Pandemic: An Analysis of Spontaneous Reports in VigiBase During 2020COVID-19 팬데믹에서의 렘데시비르: 2020년 동안 VigiBase의 자발적 보고서 분석Article Published on 2021-09-012022-09-11 Journal: Drug safety [Category] SARS, 진단, 치료제, [키워드] ADR ADRS Adverse drug reaction Adverse drug reactions Algorithm America Americas Analysis approved bradycardia collected comparator COVID-19 death demographics described Descriptive analysis Descriptive statistics disease effective indicated individual information Kidney injury liver dysfunction majority males median age Medicine Medicines Patient peaked Remdesivir report reported Retrieval Safety safety profile severity Spontaneous suggested Symptom the WHO Tocilizumab Treatment were used [DOI] 10.1007/s40264-021-01091-x PMC 바로가기 [Article Type] Article
A comprehensive analysis of the efficacy and safety of COVID-19 vaccinesCOVID-19 백신의 유효성 및 안전성에 대한 포괄적인 분석Meta-Analysis Published on 2021-09-012022-09-11 Journal: Molecular therapy : the journal of the American So [Category] MERS, SARS, 변종, 임상, 진단, [키워드] addition addressed ADR ADRS Adverse Adverse drug reaction Adverse drug reactions African American black can be used comprehensive analysis coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death doses Efficacy Efficacy and safety exceeded fatigue Grade 1 greater headache highest male MOST myocarditis Pain performed Pericarditis powerful tool reaction Reactions real-world data Reporting Research Safety SARS-CoV-2 severity Spectrum System the vaccine the vaccines thromboembolic Thromboembolic events tolerable Trial vaccination Vaccine [DOI] 10.1016/j.ymthe.2021.08.001 PMC 바로가기 [Article Type] Meta-Analysis
A prospective, observational study to evaluate adverse drug reactions in patients with COVID-19 treated with remdesivir or hydroxychloroquine: a preliminary report렘데시비르 또는 하이드록시클로로퀸으로 치료받은 COVID-19 환자의 약물 부작용을 평가하기 위한 전향적 관찰 연구: 예비 보고서Observational Study Published on 2021-09-012022-09-11 Journal: European Journal of Hospital Pharmacy [Category] 임상, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 ADR ADRS Adverse drug reaction Adverse drug reactions adverse effect Adverse reactions authorisation baseline characteristics carried Causality clinical medicine Cohort cohorts coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 cumulative drug monitoring drug-related side effects and adverse reactions Efficacy EMA European Medicines Agency evaluate greater HCQ Health authority hospital hospitalised Hydroxychloroquine implementation incidence Local Observational cohort study outbreak participant Patient patients patients with COVID-19 pharmacovigilance pharmacy service preliminary report pressure public health real-world data regimen REM Remdesivir reported safety profile SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Side effect Side effects study period Suspected System Therapeutic strategies treated Treatment treatment of COVID-19 [DOI] 10.1136/ejhpharm-2020-002613 PMC 바로가기 [Article Type] Observational Study
Cutaneous Adverse Reactions to COVID-19 Vaccines: Insights from an Immuno-Dermatological PerspectiveReview Published on 2021-08-252022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] ADR ADRS Adverse Adverse drug reaction adverse event approval arising clinical development concerning coronavirus disease Course COVID-19 COVID-19 vaccines Cutaneous cytokine profile determine Efficacy Exanthema group immunogenic reaction Inflammatory injection site insight natural infection Numerous occur outcome Patient patients performed profiles reached reaction required Research SARS-CoV-2 Side effect Specific subset T-cell Th1 Th2 Tregs type I interferons Vaccine Vaccines [DOI] 10.3390/vaccines9090944 PMC 바로가기 [Article Type] Review
High-throughput framework for genetic analyses of adverse drug reactions using electronic health records전자 건강 기록을 사용한 부작용 반응의 유전자 분석을위한 고 처리량 프레임 워크Research Article Published on 2021-06-012022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] added ADR ADRS Adverse drug reaction Adverse drug reactions Adverse reaction Adverse reactions allergy Analysis approach association associations Biobank clinical guideline Clinical guidelines common diseases conducted CYP2D6 develop DNA drug Drug allergy drug response Electronic health record Electronic health records eligible patient Eligible patients Evidence expression genetic association genetic associations genetic loci Genetic studies genetic study Genetic variation Genome-wide association studies Genome-wide association study group GWAS Healthcare system help identify IMPROVE individual less loci opioid OPRM1 pathophysiological mechanism pathophysiological mechanisms phenome physiological Precision proof Quantitative recorded Research response sample sizes understanding university [DOI] 10.1371/journal.pgen.1009593 PMC 바로가기 [Article Type] Research Article
Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysisCOVID-19 치료를 위한 렘데시비르; 업데이트된 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-04-152022-09-11 Journal: European journal of pharmacology [Category] 임상, 치료법, 치료제, [키워드] 95%CI administration ADR ADRS Adverse drug reaction Adverse drug reactions approval approved benefit bioRxiv Clinical improvement Cochrane Library controlled trials coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patients COVID-19 treatment Direct Drug administration Efficacy and safety evaluate Evidence extracorporeal membrane oxygenation FDA FIVE follow-up time Google Scholar Health Health crisis Intervention Invasive mechanical ventilation median medRxiv Meta-analysis non-randomized study oxygen oxygen support pandemic performed Performing provided Randomized controlled trial RCT RCTs regimen Remdesivir risk SARS-CoV-2 Science Science Direct scientific evidence sensitivity analysis significantly lower systematic literature search systematic review Treatment was done Web of Science [DOI] 10.1016/j.ejphar.2021.173926 PMC 바로가기 [Article Type] Meta-Analysis