Epigenetic mechanisms and host factors impact ACE2 gene expression: Implications in COVID-19 susceptibility
Research article
Published on
Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 유전자 메커니즘,
Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 유전자 메커니즘,
[키워드] ACE2 gene
ACE2 protein
age
angiotensin-converting enzyme 2
Arterial hypertension
association
Asthma
BMI
body mass index
changes in
clinical variable
clinical variables
COVID-19
COVID-19 susceptibility
described
determinant
disease susceptibility
DNA methylation
Epigenetic
epigenetics
evaluate
evaluated
expression
expression profile
Factor
Host
host cell
host factors
Infection
involved
Male sex
mechanism
Methylation
molecular cause
mRNA expression
nasopharyngeal swab sample
obesity
overexpression
Peripheral blood
promoter region
quantified
regulated
Result
risk factor
RT-qPCR
SARS-CoV-2
SARS-COV-2 infection
Sex
significant difference
smoking
study group
susceptibility
the disease
type II diabete
underlying disease
Variability
variable
virus
volunteers
was determined
[DOI] 10.1016/j.meegid.2022.105357 [Article Type] Research article
[DOI] 10.1016/j.meegid.2022.105357 [Article Type] Research article