Acute cardiac injury – Communicable Diseases Research

Multisystem inflammatory syndrome in a young adult successfully treated with plasmapheresis, immunoglobulins, and corticosteroids: a case report

Article

Published on 2022-09-012022-11-15
Journal: International Journal of Infectious Diseases [Category] 진단,

Cardiovascular markers and COVID-19

Research article

Published on 2022-08-022022-10-05
Journal: Sensors (Basel, Switzerland) [Category] 바이오마커, 진단,

Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury

공간 영역 분석 프로테옴 지도는 COVID-19 관련 심장 손상의 메커니즘을 보여줍니다

Article

Published on 2022-06-142022-09-12
Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 진단,

Outcomes of Hospitalized Patients With COVID-19 With Acute Kidney Injury and Acute Cardiac Injury

Cardiovascular Medicine

Published on 2022-02-152022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

[키워드] Accuracy ACI Acute cardiac injury Acute kidney injury adjusted AKI analyzed cardiac cardiac injury cardiovascular sequelae clinical outcomes collected common Comorbidities COVID-19 COVID-19 patient death discharge disease course groups had more Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients identify immunological incidence Inflammatory Injury Intervention investigated kidney Laboratory laboratory data Laboratory test liver longitudinal marker men Mortality MOST New York Odds ratio Older outcome Patient predict predicted Predictive Predictive model predictor Result Retrospective study risk Risk factors SARS-CoV-2 significantly System variable vitals were used
[DOI] 10.3389/fcvm.2021.798897 PMC 바로가기 [Article Type] Cardiovascular Medicine

Identification of Crucial Genes and Key Functions in Type 2 Diabetic Hearts by Bioinformatic Analysis

생물정보학적 분석을 통한 제2형 당뇨병 심장의 핵심 유전자 및 주요 기능 식별

Endocrinology

Published on 2022-02-152022-09-11
Journal: Frontiers in Endocrinology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘,

[키워드] Acute cardiac injury Analysis Autopsy Bioinformatic bioinformatic analysis bioinformatics calpain calpain small subunit 1 (capn4) CAPNS1 cardiac cardiac injury conducted COVID-19 cytoplasmic Cytoscape dataset datasets dead DEGs DESeq2 develop diabete diabetes differentially expressed gene Differentially expressed genes down-regulated endopeptidase event events exhibited expression profile expression profiles function functions Gene ontology healthy heart hearts highlight homologous Hospitalized Human hydrolysis hydrolyzed identification identify Infection Interaction Kyoto leads less mechanism membrane mice Mitochondria molecular Mybpc3 Myocardium NCBI-Gene NCBI-GEO nuclear translocation overlapping pathogenic pathway patients with SARS-CoV-2 performed PPI PPI network prognostic progression protein-protein interaction reduced RNA-sequencing SARS-COV-2 infection self-protective role Serine Signaling significantly significantly increased small subunit specimen substrate syndrome T2D therapy Tnni3 Transcription transcriptional change transcriptional level Transcriptional upregulation transcriptomics Type type 2 diabetes unique up-regulated with COVID-19
[DOI] 10.3389/fendo.2022.801260 PMC 바로가기 [Article Type] Endocrinology

Clinical predictors of acute cardiac injury and normalization of troponin after hospital discharge from COVID-19

Research article

Published on 2022-02-072022-10-05
Journal: EBioMedicine [Category] COVID19(2023년), SARS, 임상,

[키워드] Accuracy ACI Acute cardiac injury acute myocardial injury Admission average cardiovascular complications clinical collected Comorbidities COVID-19 COVID-19 patient creatinine defined demographics discharge funding groups heart failure help hospital hospital discharge Hospital stay Hospitalization hospitalized COVID-19 patient hospitalized patient incidence Injury investigated Laboratory test lactate dehydrogenase lymphocyte machine learning Mortality no significant difference Odds ratio Patient patient data patients persistent predict prediction predictor Prevent Result Retrospective study returned SARS-CoV-2 serum sodium Survivors threshold TNT Troponin-T upper reference limit were used with COVID-19
[DOI] 10.1016/j.ebiom.2022.103821 [Article Type] Research article

Emerging Role of Platelet-Endothelium Interactions in the Pathogenesis of Severe SARS-CoV-2 Infection-Associated Myocardial Injury

중증 SARS-CoV-2 감염 관련 심근 손상의 발병에서 혈소판-내피 상호작용의 새로운 역할

Review

Published on 2022-02-042022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 치료법,

[키워드] Abnormalities ACE2 ACE2 receptor activated Activation activation of platelets Acute cardiac injury acute infection acute myocardial injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition angiotensin angiotensin-converting enzyme 2 arrhythmia calcium calcium-binding proteins cardiac complication Cardiac complications cardiac disorders cardiac injury cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease cardiovascular dysfunction Clinical course Clinical outcome Coagulation contribute corona virus disease (COVID-19) coronavirus defined described disease disease pathogenesis driven by dysfunction endothelial Endotheliitis event fatal complication hypercoagulability include Infection Inflammation Interaction mechanism morbidity and mortality MOST Myocardial myocardial injury nucleocapsid nucleocapsid (N) protein occur oxygen pandemic Patient Platelet platelet activation Platelets potential mechanism potential mechanisms Prevalence Proteins respiratory risk factor Risk factors role SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 virus Sepsis severe acute respiratory syndrome Coronavirus severe disease significantly Spike protein systemic inflammation the SARS-CoV-2 virus triggering turn Vascular endothelium Viral viral spike protein virus
[DOI] 10.3389/fimmu.2022.776861 PMC 바로가기 [Article Type] Review

Relationship between lung injury extent and phenotype manifested in non-contrast CT and cardiac injury during acute stage of COVID-19

Research article

Published on 2022-02-012022-10-05
Journal: IJC Heart & Vasculature [Category] 바이오마커, 진단,

[키워드] Accuracy ACI Acute cardiac injury Biomarker Blood blood oxygen level blood test C-reactive protein (CRP correlation COVID-19 COVID-19 patients CRP CRP level diagnostic value evaluated exhibited Heart injury immunological Inflammation Inflammatory Injury investigated linear lung Lung injury lung parenchyma lymphocyte manifested Non-contrast computed tomography (NCCT) PaO2 parameter Patient patients patients with COVID-19 phenotype predictor relationship Result SARS-CoV-2 significantly higher significantly lower statistically significant suggested symptom onset the patient tissue troponin I viral infection Volume was determined
[DOI] 10.1016/j.ijcha.2021.100938 [Article Type] Research article

Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19

중요한 COVID-19에서 심장 손상 및 미세 혈전에 대한 임상 조직 병리학 및 단일 핵 RNA 시퀀싱 통찰력

Clinical Trial

Published on 2022-01-252022-09-10
Journal: JCI Insight [Category] 임상, 진단, 치료기술, 치료제,

[키워드] Acute cardiac injury Analysis antiplatelet association bioinformatics Biomarkers biomarkers of inflammation C-reactive protein cardiac injury Cardiology cardiovascular disease cause clinical factors Cohort conducted controls Corticosteroid corticosteroid treatment COVID-19 Critical enrichment erythrocyte sedimentation erythrocyte sedimentation rate etiology Extracellular matrix Features fibrinolysis fibroblast heart hearts identify In-hospital increased mortality Injury microthrombi Molecular pathology myocarditis Necrosis New York City pathophysiology Patient potential therapeutic target prevalent Prospective Study RNA-sequencing sedimentation rate Sequencing analysis Signaling tested therapeutic anticoagulation Therapies therapy transcriptomic were used
[DOI] 10.1172/jci.insight.154633 PMC 바로가기 [Article Type] Clinical Trial

Cardiovascular System during SARS-CoV-2 Infection

Review

Published on 2022-01-212022-10-30
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,